PURPOSE: To compare measurements of the sagittal diameter lumbar dural sac obtained at positional magnetic resonance (MR) imaging and functional myelography to assess influence various body positions on intervertebral foramina. MATERIALS AND METHODS: Thirty consecutive patients referred for were examined with an open 0.5-T MR imager, Sagittal T2-weighted fast spin-echo images acquired in supine, upright flexion, extension positions. The midsagittal was measured level disks myelograms....

Aim: Evaluation of the delivery gentamicin and vancomycin from polymethylmethacrylate (PMMA) spacers before after implantation for treatment total hip replacement infections.

Chronic functional constipation is common in infants, and the bacterial composition of stools this condition not known. The study aims were to: (i) investigate intestinal ecosystem chronic constipation; (ii) establish whether addition water‐holding agent calcium polycarbophil to diet induces an improvement (iii) determine after use agent. In total, 42 children (20F, 22M; mean age: 8.6 ± 2.9 y) studied. Twenty‐eight with without anatomical disorders treated double‐blind random sequence for 1...

The aim of the study was to verify whether antibiotics excreted by normal pancreas are also in human necrotizing pancreatitis, reaching tissue sites infection. Twelve patients suffering from acute pancreatitis were treated with imipenem-cilastatin (0.5 g), mezlocillin (2 gentamicin (0.08 amikacin pefloxacin (0.4 and metronidazole g). Serum necrotic samples collected simultaneously at different time intervals after parenteral drug administration computed tomography-guided needle aspiration,...

The effects of probiotics on human health are positive and well defined in diarrhoea treatment. There no clinical results regarding the relationship with dose or duration from studies have not been conclusive that probiotic dependent strains, acute chronic gastrointestinal infection immunological inflammatory disease different concentration needed to obtain a effect is often quoted as≥106 cfu/ml small bowel and≥108 cfu/g colon. for treatment an illness by particular agent may be lower...

The effects of probiotics on human health are positive and well defined in diarrhoea treatment. There no clinical results regarding the relationship with dose or duration from studies have not been conclusive that probiotic dependent strains, acute chronic gastrointestinal infection immunological inflammatory disease different concentration needed to obtain a effect is often quoted as  ≥ 10 ?  cfu/ml small bowel and  ?  cfu/g colon. for treatment an illness by particular agent may be lower...

Objective To investigate the presence of bacteria and fungi in bronchial aspirate (BA) samples from 43 mechanically ventilated patients with severe COVID-19 disease. Methods Detection SARS-CoV-2 was performed using Allplex 2019-nCoV assay kits. Isolation characterisation were carried out BA specimens treated 1X dithiothreitol 1% for 30 min at room temperature, standard culture procedures. Results Bacterial and/or fungal superinfection detected 25 patients, generally after 7 days...

Chronic functional constipation is common in infants, and the bacterial composition of stools this condition not known. The study aims were to: (i) investigate intestinal ecosystem chronic constipation; (ii) establish whether addition water-holding agent calcium polycarbophil to diet induces an improvement (iii) determine after use agent. In total, 42 children (20F, 22M; mean age: 8.6 +/- 2.9 y) studied. Twenty-eight with without anatomical disorders treated double-blind random sequence for...

The increase in resistance rates to antibiotics of bacteria isolated from infected hip joints, particularly staphylococci, prompted us investigate the usefulness antibiotic combinations such as gentamicin plus vancomycin. Cylinder test specimens polymethylmethacrylate (PMMA) cement (Cemex, Tecres) containing alone, vancomycin alone and both drugs combination, were studied. concentrations determined using a microbiological method fluorescence polarization immunoassay (FPIA). release...

Gentamicin (G) and vancomycin (V) concentrations in drainage fluids obtained from patients during the first 24 hours after implantation of antibiotic‐loaded polymethylmethacrylate (PMMA) spacers two‐stage revision infected total hip arthroplasty were studied. The inhibitory activity against different multiresistant clinical isolates was investigated as well. Seven hips treated by industrial G‐loaded spacers. Vancomycin added manually mixing with PMMA bone cement. Serum fluid samples...

Gentamicin (G) and vancomycin (V) concentrations in joints fluids obtained from patients during the first 24 hours after implantation of antibiotic-loaded polymethylmethacrylate (PMMA) spacers two-stage revision for infected arthroplasty, inhibitory activity joint against different multiresistant clinical isolates were studied. A total 12 undergoing surgery with industrial G added amounts V was Serum fluid samples collected 1, 4, spacer implantation. Antibiotics bactericidal titer (JBT)...

Abstract Local antibiotic diffusion in rabbit femurs from two new PMMA‐based and nail‐shaped composites, enriched with β‐tricalcium phosphate (P‐TCP) BaSO 4 or only (P‐BaSO ), soaked a solution of gentamicin (G) vancomycin (V) was studied. Nails were implanted into the intramedullary cavity healthy osteomyelitic to study resolution infection quantify penetration bone by microbiological, pharmacological, histological tests. A significant progression osteomyelitis recorded 7 weeks after MRSA...

AbstractA technique is described for lumbar canal stenosis and disc protrusion combining safe selective decompression translaminar screw fixation. After experience with 166 cases from 1987 to 1991 we consider this particularly suitable the treatment of spinal also few displacement which need a primary fusion.Key Words: Lumbar stenosisposterior fusiontranslaminar fixationlumbar instabilitylumbar

An effective approach in the treatment of benzodiazepine (BZD) overdosing and detoxification is flumazenil (FLU). Studies chronic users who discontinued BZD a clinical setting suggested that multiple slow bolus infusions FLU reduce withdrawal symptoms. The aim this study was to confirm efficacy for reducing syndrome by means continuous elastomeric infusion, correlated drugs plasma level patients' compliance. Methods: Seven-day 1 mg/day subcutaneously injected through an pump BZDs...

Pancreatic juice (PJ) should be a factor of variability in the antimicrobial activity antibiotics eliminated by pancreas during pancreatic infections. We studied its effects on drugs with different mechanisms action. Samples pure PJ were collected from 16 patients stabilized external fistulas. The at concentrations (from 1.25 to 100%) alone and combination mezlocillin, imipenem, ceftriaxone, gentamicin, ofloxacin, ciprofloxacin was microbiological method (continuous turbidimetric recording...

Antibiotic prophylaxis may be useful in acute necrotising pancreatitis, a disease associated with considerable incidence of infectious complications. The aim this study was to assess pefloxacin penetration into necrotic pancreatic tissue during human pancreatitis. Ten patients (mean age 53·2 ± 17·4 years) severe pancreatitis Ranson score 4·3) were studied. Pefloxacin administered at dose 400 mg bd every 12 h by iv infusion (bolus, 15 min). Intraoperative samples and blood collected...

Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder caused by mutations in the MCOLN1 gene coding for mucolipin-1 (TRPML1). TRPML1 belongs to a transient receptor potential channels (TRP) subfamily, which mammals includes two other members: mucolipin-2 (TRPML2) and mucolipin-3 (TRPML3). Bioinformatic analysis of Danio rerio (zebrafish) genome trascriptome revealed presence five different genes related human mucolipins: mcoln1.1, mcoln1.2, mcoln2, mcoln3.1...