A5114533492- Obsessive-Compulsive Spectrum Disorders
- Neurological disorders and treatments
- Transcranial Magnetic Stimulation Studies
- Body Image and Dysmorphia Studies
- Functional Brain Connectivity Studies
- Psychosomatic Disorders and Their Treatments
- EEG and Brain-Computer Interfaces
- Treatment of Major Depression
University of California, San Francisco
2025
Université Grenoble Alpes
2024
Laboratoire de Psychologie et NeuroCognition
2024
Centre National de la Recherche Scientifique
2024
Abstract Deep brain stimulation has been used to treat severe, refractory obsessive-compulsive disorder (OCD) with variable outcomes across multiple anatomical targets. To overcome these limitations, we developed an invasive mapping paradigm in which electrodes were implanted the OCD cortico-striato-thalamo-cortical circuit a single individual. We then performed extensive during multi-day inpatient stay identify personalized therapeutic targets and characterize their downstream effects....
Abstract Most human studies on perceptual decision-making are correlational, and few addressed the causal role of neural markers they identify. Here, we took opportunity offered by deep brain stimulation to study subthalamo-cortical networks monitoring. To this end, asked participants with obsessive-compulsive disorder (OCD) treated subthalamic detect visual stimuli provide confidence reports while recorded scalp electroencephalography. Following a preregistered plan, compared behavioural...