Introduction: To compare short- and midterm outcomes of the first 55 patients undergoing robot-assisted kidney transplant (RAKT) with open (OKT) during same period in a tertiary care hospital. Materials Methods: Data all end-stage renal disease were prospectively maintained. All graft kidneys harvested laparoscopically. Both RAKT OKT performed using standardized techniques, RAKTs by single experienced robotic surgeon. Chi-square test/Fisher exact test was done for categorical data,...

Diagnosis of rejection in small bowel transplantation by the identification a host-cell infiltrate is hampered physiological trafficking host lymphocytes to 'gut-associated lymphoid tissue' graft. This study compared infiltration grafts with that occurring and stable immunosuppression. Physiological infiltration, where graft does not present an immune stimulus host, was assessed transplanting from DA (DA x PVG) F1 hybrid rats. The extent determined immunohistochemical analysis. In lamina...

Abstract Between August 1990 and January 1992, 184 patients with squamous cell carcinoma of the cervix, FIGO stage IIBIV A were randomised (study 1) to receive either two cycles bleomycin, ifosfamide‐mesna cisplatin (BIP) chemotherapy (CT) followed by radiotherapy (RT) ‘CT‐RT Group’ a=94 or RT alone, Group n=90. In Group’, evaluable 89 patients, 64 responded: complete response (CR) four (4.5%) partial (PR) 60 (67.5%). Of remaining 25 23 had stable disease progressed. Eighty completed as...

To look for the frequency and pattern of neuropathy in Indian patients with rheumatoid arthritis (RA). One hundred newly diagnosed RA (ACR 1987 revised criteria) visiting our hospital, over a period 3 years were screened. Diabetics, outstation patients, chronic alcoholics, those any known cause peripheral having an overlap other rheumatological illness excluded. Clinical assessment included detailed history examination special reference to extra-articular features relevant clinical...

Complement Receptor 1 (CR1) is a key complement regulatory protein (CRP) involved in the clearance of immune complexes. Earlier, we reported marked decline leukocyte CR1 (L-CR1) transcript and patients with active systemic lupus erythematosus (SLE) suggested L-CR1 as putative non-invasive disease marker for SLE. This follow-up study involving 18 SLE was conducted further confirmation relationship between Blood samples from were collected on day diagnosis (0 month) at different time intervals...

Corticosteroids form the mainstay of therapy for all forms nephrotic syndrome. The long-term use this medication is associated with serious side effects including adrenocortical suppression. primary objective study was to identify suppression (assessed by single morning serum cortisol levels) in children syndrome on treatment low-dose alternate day steroids. This cross-sectional conducted Department Pediatrics a tertiary care hospital from January 2014 2015. Seventy (1-18 years) (steroid...

To establish DAS 28 and 28-3 scores that best define remission in Indian patients with rheumatoid arthritis (RA). All diagnosed RA visiting AIIMS, New Delhi over a period of 3 months were recruited. Clinical assessment included joint counts for swelling tenderness, duration early morning stiffness, patient global disease activity, fatigue, pains ESR. calculated receiver operating characteristics curve analysis was performed to cutoff values utilizing ‘ACR 5/6’ 4/5’ criteria. Subjects 207 (M:...

A number of drugs have been tried for the relief sicca symptoms in Sjøgren's syndrome (SS) without much benefit. Lately, oral pilocarpine, a muscarinic cholinergic agent, has reported to be useful. To document effect pilocarpine on patients with SS. The study group comprised 41 (4 men and 37 women) diagnosed as SS (primary or secondary) according European criteria. Patients were recruited from rheumatology clinic, cornea medicine OPD AIIMS between April 2003 March 2005. Study subjects...

The assessment of disease activity in patients with ankylosing spondylitis (AS) continues to be a challenging issue. currently available markers like C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) show poor correlation clinical activity. There is need for good biomarkers assess We explored serum nitrite, stable end product metabolism NO, which known rise inflammation, as potential biomarker AS. To compare the levels nitrite between AS healthy controls correlate four (ASAS)...

Spondyloarthropaties (SpA) are a diverse group of disorders characterized by inflammatory low backache, genetic predisposition and variety articular extraarticular manifestations. Evidence sacroiliitis in plain radiographs forms the cornerstone for establishing diagnosis. However, it may take many years to become visible. With availability biologics that have potential modify course SpAs, there is need early diagnosis these disorders. Magnetic resonance imaging (MRI) nuclear scintigraphy...

The natural history of Complex Regional Pain Syndrome (CRPS) is not well understood and the progression varies between different patients. pathogenesis this disorder a single mechanism can barely account for all changes that are seen. In absence any pathognomonic sign or investigation, diagnosis suggested by presence constellation symptoms, signs laboratory findings. It often under-diagnosed undertreated resulting in significant morbidity impaired quality life. crux management lies...

To evaluate large-vessel (LV) abnormalities on serial imaging in patients with giant cell arteritis (GCA) and discern predictors of new lesions.Clinical data from GCA (including subjects diagnosed by LV imaging) enrolled a prospective, multicenter, longitudinal study and/or randomized clinical trial were included. New arterial lesions defined as lesion previously unaffected artery.The included 187 GCA, 146 (78%) female, mean (±SD) age at diagnosis 68.5 ± 8.5 years; 39% imaging. At least one...