A5033012867- Diabetes, Cardiovascular Risks, and Lipoproteins
- Fatty Acid Research and Health
- Lipoproteins and Cardiovascular Health
- Global Public Health Policies and Epidemiology
- Birth, Development, and Health
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Chronic Kidney Disease and Diabetes
- Neonatal Respiratory Health Research
- Climate Change and Health Impacts
- Healthcare Systems and Reforms
- Air Quality and Health Impacts
- Health disparities and outcomes
- Sodium Intake and Health
- Cardiac Arrest and Resuscitation
- Adipokines, Inflammation, and Metabolic Diseases
- Gestational Diabetes Research and Management
- Cardiovascular Disease and Adiposity
- Cholesterol and Lipid Metabolism
- Diabetes and associated disorders
- Health Systems, Economic Evaluations, Quality of Life
- Rheumatoid Arthritis Research and Therapies
- Vitamin D Research Studies
Medical College of Wisconsin
2016-2025
Centre for Chronic Disease Control
2012-2024
Public Health Foundation of India
2014-2024
All India Institute of Medical Sciences
2008-2024
Purbanchal University
2024
Ashoka University
2024
All India Institute of Medical Sciences Raipur
2024
All India Institute of Medical Sciences Bhopal
2024
Children's Hospital of Wisconsin
2016-2023
Johns Hopkins Medicine
2023
Sleep duration and disturbances may be risk factors for hypertension. Despite the high burden of hypertension in South Asia, little is known about this relationship region. We analyzed population-level cross-sectional data from Centre Cardiometabolic Risk Reduction Asia (CARRS) study that recruited representative samples adults ≥ 20 years three cities—Delhi, Chennai (India), Karachi (Pakistan) during 2010–2011. defined as self-reported treatment or measured blood pressure (BP) ≥140/90 mm Hg....
<h3>Background and objectives</h3> Despite being one of the leading risk factors cardiovascular mortality, there are limited data on changes in hypertension burden management from India. This study evaluates trend prevalence, awareness, treatment control urban rural areas India's National Capital Region (NCR). <h3>Design setting</h3> Two representative cross-sectional surveys were conducted (survey 1 (1991–1994); survey 2 (2010–2012)) NCR using similar methodologies. <h3>Participants</h3> A...
Despite high projected burden, hypertension incidence data are lacking in South Asian population. We measured prevalence and the Center for cArdio-metabolic Risk Reduction Asia (CARRS) adult cohort. The CARRS Study recruited representative samples of Chennai, Delhi, Karachi 2010/11, socio-demographic risk factor were obtained using a standard common protocol. Blood pressure (BP) was sitting position electronic sphygmomanometer both at baseline two year follow-up. Hypertension control defined...
Background We comparatively assessed the performance of six simple obesity indices to identify adults with cardiovascular disease (CVD) risk factors in a diverse and contemporary South Asian population. Methods 8,892 participants aged 20–60 years 2010–2011 were analyzed. Six examined: body mass index (BMI), waist circumference (WC), waist-height ratio (WHtR), waist-hip (WHR), log sum triceps subscapular skin fold thickness (LTS), percent fat derived from bioelectric impedance analysis (BIA)....
The Andhra Pradesh Children and Parents Study (APCAPS) was originally established to study the long-term effects of early-life undernutrition on risk cardiovascular disease. Its aims were subsequently expanded include trans-generational influences other environmental genetic factors chronic diseases in rural India. It builds Hyderabad Nutrition Trial (HNT) conducted 1987–90 compare birthweight a protein-calorie supplement for pregnant women children. index children HNT their mothers retraced...
Objectives To assess whether chronic kidney disease of unknown aetiology (CKDu) is present in India and to identify risk factors for it using population-based data standardised methods. Design Secondary analysis three cross-sectional studies conducted between 2010 2014. Setting Urban rural areas Northern (states Delhi Haryana) Southern Tamil Nadu Andhra Pradesh). Participants 12 500 individuals without diabetes, hypertension or heavy proteinuria. Outcome measures Mean estimated glomerular...
Why was the cohort set up?2][13] In addition, South Asia exhibits differences in health service use, care costs and quality of compared with high-income countries (HICs). 14Well-characterized prospective epidemiological cohorts help study natural history diseases evolution region.This can advance knowledge science cardiometabolic provide infrastructure for interdisciplinary dynamic scientific explorations. 15he Center cArdiometabolic Risk Reduction (CARRS) is a population-based...
Genetic deficiency of acid a-glucosidase (GAA) results in Pompe disease (PD) encompassing four clinical subtypes varying severity. Our objective is to develop an innovative and affordable approach for enzyme replacement therapy (ERT) through oral administration (Oral-ERT) maintain a sustained therapeutic level daily improve treatment efficacy. Tobacco seeds contain the metabolic machinery compatible with mammalian glycosylation-phosphorylation. We have shown that transgenic tobacco...
Objective: The World Health Organization (WHO) recommends reducing dietary salt intake to <5gm/d as a cost-effective strategy reduce hypertension and associated cardiovascular diseases. However, is also used vehicle for iodine supplementation preventing deficiency disorders (IDD). Concerns have been expressed that population will adversely impact levels. Therefore, the aim of this paper was estimate daily consumption levels adult in India examine effect WHO recommended on Methods: A...
Introduction Diabetes and hypertension are two leading non-communicable conditions, which suboptimally managed in India. Thus, innovative comprehensive approaches that can concomitantly improve their detection, prevention control warranted. Methods analysis UDAY, a 5-year initiative, aims to reduce the risk of diabetes management by implementing intervention programme selected study sites, Sonipat Visakhapatnam (Vizag). It has pre-post evaluation design with representative cross-sectional...
<b>Objective</b> This study aims to determine the frequency that umbilical venous catheters (UVCs) and peripherally inserted central (PICCs) migrate into cardiothymic silhouette after initial verification of correct placement. <b>Study Design</b> is a single-center, retrospective in neonates whom PICC or UVC was placed. The catheter tip migration requiring manipulation determined radiographically at 1 24 hours, respectively, insertion. <b>Results</b> At 36 23% UVCs (<i>n</i> = 41) migrated...
Global Heart is the official and primary publication of World Federation, offering a platform for dissemination knowledge on research, developments, trends, solutions public health programmes in area cardiovascular disease. welcomes research results, points view educational material prevention, treatment control disease with special focus low middle-income countries which are facing brunt epidemiological transition.Global strongly encourages authors to adhere CONSORT, STROBE, STARD, PRISMA...
Introduction Although deaths due to chronic kidney disease (CKD) have doubled over the past two decades, few data exist inform screening strategies for early detection of CKD in low-income and middle-income countries. Methods Using from three population-based surveys India, we developed a prediction model identify target population that could benefit further testing, after an initial implemented during home health visits. one urban survey (n=8698), applied stepwise logistic regression test...
Dietary patterns (DPs) in India are heterogenous. To date, data on association of indigenous DPs with risk factors nutrition-related noncommunicable diseases (cardiovascular disease and diabetes), leading causes premature death disability, limited. We aimed to evaluate the associations empirically-derived blood lipids, fasting glucose pressure levels an adult Indian population recruited across four geographical regions India. used cross-sectional from Migration Study (2005–2007)....
Exposure to ambient PM
The present study was designed to evaluate the independent and interactive effects of a once-a-day yoghurt drink providing 2 g plant sterols/d capsules fish oil n-3 long-chain (LC) PUFA/d on plasma lipids, apolipoproteins LDL particle size. Following 2-week run-in period, 200 mildly hypercholesterolaemic Indian adults aged 35-55 years were randomised into one four groups x factorial, double-blind controlled trial. 4-week treatments consisted (1) control capsules, (2) (3) sterol-enriched or...
Background: Glycated hemoglobin A1c (A1C) is an important marker in the diagnosis and treatment of diabetes. Dried blood measurement A1C useful large scale epidemiological evaluation A1C, especially to assess impact intervention programs. The possibility using dried for by immunoturbidimetric method was explored present study. Method: Blood collected from 30 patients, spots were prepared dried. spot samples kept different lengths time at 4°C stability. measured whole on day collection as...
Developing countries are facing a rise in noncommunicable diseases (NCD), which is cause for concern. The World Health Organization has recommended stepwise approach NCD risk factor surveillance. Screening factors remote populations difficult due to lack of resources and technical expertise, including standardized laboratory facilities. collection samples on filter paper the assessment circumvents need blood processing, storage, shipment at ultralow temperatures.Samples were collected 3-mm...
Independent and combined effects of 2 g/d long chain omega-3 fatty acids (omega-3) from fish oil (capsules) plant sterol (yogurt drink) on LDL-C non-HDL-C levels in Indian subjects were compared. Following a 2-week run-in period, 200 mildly hypercholesterolemic (total cholesterol 5.0–8.0 mmol/l) adults (35–55 years) randomized into one four groups [(1) both placebo (2) active (3) (4) active] × factorial, double-blind, placebo-controlled trial. Blood samples obtained before after the 4-week...
Background While data from the latter part of twentieth century consistently showed that immigrants to high-income countries faced higher cardio-metabolic risk than their counterparts in low- and middle-income countries, urbanization associated lifestyle changes may be changing these patterns, even for conditions considered advanced manifestations disease (e.g., chronic kidney [CKD]). Methods findings Using cross-sectional Center cArdiometabolic Risk Reduction South Asia (CARRS, n = 5294)...