A5061652194- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Occupational and environmental lung diseases
- Health disparities and outcomes
- Respiratory and Cough-Related Research
- Allergic Rhinitis and Sensitization
- Occupational exposure and asthma
- Climate Change and Health Impacts
- Global Public Health Policies and Epidemiology
- Carcinogens and Genotoxicity Assessment
- Health, Environment, Cognitive Aging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 epidemiological studies
- Global Health Care Issues
- Global Cancer Incidence and Screening
- Advanced Causal Inference Techniques
- Vaccine Coverage and Hesitancy
- Indoor Air Quality and Microbial Exposure
- SARS-CoV-2 and COVID-19 Research
- Occupational Health and Safety Research
- Health Systems, Economic Evaluations, Quality of Life
- Employment and Welfare Studies
- School Health and Nursing Education
- Pediatric health and respiratory diseases
- Infection Control and Ventilation
London School of Hygiene & Tropical Medicine
2016-2025
University of London
2016-2025
Massey University
2013-2024
Aarhus University
2020-2024
Leiden University Medical Center
2012-2024
Deakin University
2021-2023
Faculty of Public Health
2023
University Hospital Southampton NHS Foundation Trust
2012-2022
University of Auckland
1992-2022
Institute of Occupational Medicine
2002-2022
The aetiology of asthma and allergic disease remains poorly understood, despite considerable research. International Study Asthma Allergies in Childhood (ISAAC), was founded to maximize the value epidemiological research into disease, by establishing a standardized methodology facilitating international collaboration. Its specific aims are: 1) describe prevalence severity asthma, rhinitis eczema children living different centres, make comparisons within between countries; 2) obtain baseline...
<b>Background:</b> Phase I of the International Study Asthma and Allergies in Childhood (ISAAC) was designed to allow worldwide comparisons prevalence asthma symptoms. In phase III survey repeated order assess changes over time. <b>Methods:</b> The after an interval 5–10 years 106 centres 56 countries children aged 13–14 (n = 304 679) 66 37 6–7 193 404). <b>Results:</b> mean symptom current wheeze last 12 months changed slightly from 13.2% 13.7% year age group (mean increase 0.06% per year)...
There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the factors, and if has been performed, then a "matched analysis" is required. However, study does not control for factors; fact it can introduce factors even when did exist source population. Thus, matched design may require controlling analysis. case requires Provided there no problems of sparse data, be obtained, with loss validity possible increase precision, using...
Background: As part of the International Study Asthma and Allergies in Childhood (ISAAC), prevalence surveys were conducted among representative samples school children from locations Europe, Asia, Africa, Australasia, North South America. Subjects: 257,800 aged 6‐7 years 91 centres 38 countries, 463,801 13‐14 155 56 countries. Methods: Written symptom questionnaires translated English into local language for self‐completion by 13‐14‐year‐olds completion parents 6‐7‐year‐olds. Rhinitis was...
About 334 million people worldwide suffer from asthma, and this figure may be an underestimation. It is the most common chronic disease in children. Asthma among top 20 conditions for global ranking of disability-adjusted life years children; mid-childhood ages 5-14 it 10 causes. Death rates asthma children globally range 0.0 to 0.7 per 100 000. There are striking variations prevalence symptoms (wheeze past 12 months) children, with up 13-fold differences between countries. Although more...
To test blood and CSF neurofilament light chain (NfL) levels in relation to disease progression survival amyotrophic lateral sclerosis (ALS).
Phase One of the International Study Asthma and Allergies in Childhood (ISAAC) measured global patterns prevalence severity symptoms rhinoconjunctivitis children 1993-1997.International Three was a cross-sectional survey performed 5-10 years after using same methodology. covered all major regions world involved 1 059 053 2 age groups from 236 centres 98 countries.The average overall current 14.6% for 13- to 14-year old (range 1.0-45%). Variation severe observed between 0.0-5.1%) 0.4% western...
There is a need for standardized approach to international and regional comparisons of the prevalence severity asthma, monitoring asthma morbidity over time. In 1991, written video questionnaires were developed administered in surveys schoolchildren, aged 12-15 yrs, five regions four countries: Adelaide, Australia (n = 1,428); Sydney, 1519); West Sussex, England 2,097); Bochum, Germany 1928); Wellington, New Zealand 1863). The self-reported wheezing during previous 12 months was similar...
In the Global Burden of Disease Study 2013 (GBD 2013), knowledge about health and its determinants has been integrated into a comparable framework to inform policy. Outputs this analysis are relevant current policy questions in England elsewhere, particularly on inequalities. We use GBD data mortality causes death, disease injury incidence prevalence analyse burden as whole, English regions, within each region by deprivation quintile. also assess attributable potentially preventable risk...
Sub-Saharan Africa is in rapid demographic transition, and non-communicable diseases are increasingly important causes of morbidity mortality. We investigated the burden diabetes, overweight obesity, hypertension, multimorbidity, their treatment, associations with lifestyle other factors Malawi, a very poor country predominantly rural-but rapidly growing urban-population, to identify high-risk populations inform appropriate interventions.