Edwin A. Mitchell

ORCID: 0000-0001-6187-7648
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About
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Research Areas
  • Neuroscience of respiration and sleep
  • Neonatal Respiratory Health Research
  • Infant Health and Development
  • Birth, Development, and Health
  • Restraint-Related Deaths
  • Maternal Mental Health During Pregnancy and Postpartum
  • Asthma and respiratory diseases
  • Maternal and Perinatal Health Interventions
  • Obesity, Physical Activity, Diet
  • Neonatal and fetal brain pathology
  • Breastfeeding Practices and Influences
  • Grief, Bereavement, and Mental Health
  • Smoking Behavior and Cessation
  • Gestational Diabetes Research and Management
  • Sleep and related disorders
  • Child and Adolescent Health
  • Infant Development and Preterm Care
  • Homelessness and Social Issues
  • Probiotics and Fermented Foods
  • Pediatric health and respiratory diseases
  • Dermatology and Skin Diseases
  • Respiratory and Cough-Related Research
  • Child and Adolescent Psychosocial and Emotional Development
  • Inhalation and Respiratory Drug Delivery
  • Food Allergy and Anaphylaxis Research

University of Auckland
2015-2024

University of Manchester
1969-2021

Manchester University NHS Foundation Trust
2021

Manchester Academic Health Science Centre
2021

University of Huddersfield
2021

Calderdale and Huddersfield NHS Foundation Trust
2021

Liverpool Women's Hospital
2021

Liverpool Womens NHS Foundation Trust
2021

University of Liverpool
2021

Michigan Medicine
2020

<b>Background:</b> Phase I of the International Study Asthma and Allergies in Childhood (ISAAC) was designed to allow worldwide comparisons prevalence asthma symptoms. In phase III survey repeated order assess changes over time. <b>Methods:</b> The after an interval 5–10 years 106 centres 56 countries children aged 13–14 (n = 304 679) 66 37 6–7 193 404). <b>Results:</b> mean symptom current wheeze last 12 months changed slightly from 13.2% 13.7% year age group (mean increase 0.06% per year)...

10.1136/thx.2006.070169 article EN Thorax 2007-05-16

The definition of sudden infant death syndrome (SIDS) originally appeared in 1969 and was modified 2 decades later. During the following 15 years, an enormous amount additional information has emerged, justifying refinement SIDS to incorporate epidemiologic features, risk factors, pathologic ancillary test findings. An expert panel pediatric forensic pathologists pediatricians considered these issues developed a new general for administrative vital statistics purposes. then stratified...

10.1542/peds.114.1.234 article EN PEDIATRICS 2004-07-01

Background: As part of the International Study Asthma and Allergies in Childhood (ISAAC), prevalence surveys were conducted among representative samples school children from locations Europe, Asia, Africa, Australasia, North South America. Subjects: 257,800 aged 6‐7 years 91 centres 38 countries, 463,801 13‐14 155 56 countries. Methods: Written symptom questionnaires translated English into local language for self‐completion by 13‐14‐year‐olds completion parents 6‐7‐year‐olds. Rhinitis was...

10.1111/j.1399-3038.1997.tb00156.x article EN Pediatric Allergy and Immunology 1997-11-01

To measure sleep duration in 7-year-old children; identify the determinants of duration; and assess association between short obesity, cognitive functioning, behaviour. Longitudinal study with disproportionate sampling participants. Community. 591 seven-year-old children, whom 519 had complete data. Not applicable. Sleep was assessed by actigraphy. Other measurements included height, weight, BMI, percentage body fat as bioimpedance assay, intelligence (WISC-III) behaviour (Strengths &...

10.1093/sleep/31.1.71 article EN SLEEP 2008-01-01

BackgroundProbiotics may help to prevent symptoms of anxiety and depression through several putative mechanisms.ObjectiveThe aim this study was evaluate the effect Lactobacillus rhamnosus HN001 (HN001) given in pregnancy postpartum on maternal period. This a secondary outcome, primary outcome being eczema offspring at 12 months age.Design, Setting, ParticipantsA randomised, double-blind, placebo-controlled trial postnatal mood conducted 423 women Auckland Wellington, New Zealand. Women were...

10.1016/j.ebiom.2017.09.013 article EN cc-by-nc-nd EBioMedicine 2017-09-14

To resolve uncertainty as to the risk of Sudden Infant Death Syndrome (SIDS) associated with sleeping in bed your baby if neither parent smokes and is breastfed.Bed sharing was defined a parents' bed; room room. Frequency during last sleep compared between babies who died SIDS living control infants. Five large case-control datasets were combined. Missing data imputed. Random effects logistic regression controlled for confounding factors.Home arrangements infants 19 studies across UK, Europe...

10.1136/bmjopen-2012-002299 article EN cc-by-nc BMJ Open 2013-05-01

Maternal smoking during pregnancy is an established risk factor for sudden unexpected infant death (SUID). Here, we aim to investigate the effects of maternal prepregnancy smoking, reduction pregnancy, and on SUID rates.We analyzed Centers Disease Control Prevention Birth Cohort Linked Birth/Infant Death Data Set (2007-2011: 20 685 463 births 19 127 SUIDs). was defined as deaths at <1 year age with International Classification Diseases, 10th Revision codes R95 (sudden syndrome), R99...

10.1542/peds.2018-3325 article EN PEDIATRICS 2019-03-11

Objectives. To identify the risk factors for sudden infant death syndrome (SIDS) following a national campaign to prevent SIDS. Methods. For 2 years (October 1, 1991 through September 30, 1993) data were collected by community child health nurses on all infants born in New Zealand at initial contact and months. Results. There 232 SIDS cases postneonatal age group (2.0/1000 live births) these compared with 1200 randomly selected control subjects. Information was available 127 (54.7%) 922...

10.1542/peds.100.5.835 article EN PEDIATRICS 1997-11-01

OBJECTIVES--To investigate why sharing the bed with an infant is a not consistent risk factor for sudden death syndrome in ethnic subgroups New Zealand and to see if of associated this practice related other factors, particularly maternal smoking alcohol consumption. DESIGN--Nationwide case-control study. SETTING--Region 78% all births during 1987-90. SUBJECTS--Home interviews were completed parents 393 (81.0% total) infants who died from postneonatal age group, 1592 (88.4% controls...

10.1136/bmj.307.6915.1312 article EN BMJ 1993-11-20

Maternal smoking has been shown to be a risk factor for sudden infant death syndrome (SIDS). The effect of by the father and other household members not previously examined.A large nationwide case-control study. Four hundred eighty-five SIDS deaths in postneonatal age group were compared with 1800 control infants.Infants mothers who smoked during pregnancy had 4.09 (95% confidence interval [CI] = 3.28, 5.11) greater than infants did smoke. Infants postnatally also an increased nonsmokers...

10.1542/peds.91.5.893 article EN PEDIATRICS 1993-05-01

This study compared 48 hyperactive children with 49 age-and-sex-matched controls. Significantly more had auditory, visual, language, reading, and learning difficulties, the birth weight of was significantly lower than that controls (3,058 3,410 g, respectively; p &lt; 0.01). In addition, frequent coughs colds, polydypsia, polyuria, a serious illness or accident in past year controls, but there no increase asthma, eczema, other allergies. Serum essential fatty acid (EFA) levels were measured...

10.1177/000992288702600805 article EN Clinical Pediatrics 1987-08-01

BACKGROUND. In the last 20 years, prevention campaigns to reduce risk of sudden infant death syndrome were very successful. some countries advice breastfeed is included in campaigns' messages, but other it not. OBJECTIVE. To examine association between type feeding and syndrome. METHODS. The German Study Sudden Infant Death a case-control study 333 infants who died 998 age-matched controls. RESULTS. A total 49.6% cases 82.9% controls breastfed at 2 weeks age. Exclusive breastfeeding 1 month...

10.1542/peds.2008-2145 article EN PEDIATRICS 2009-03-01

This study explored the effects of maternal probiotic supplementation on immune markers in cord blood (CB) and breast milk.CB plasma milk samples were collected from a cohort women who had received daily supplements either 6 x 10(9) CFU/day Lactobacillus rhamnosus HN001 (n=34), 9 Bifidobacterium lactis HN019 (n=35) or placebo (n=36) beginning 2-5 weeks before delivery continuing for months lactating women. CB (collected at 3-7 days, 3 postpartum) assayed cytokines (IL-13, IFN-gamma, IL-6,...

10.1111/j.1365-2222.2008.03061.x article EN Clinical & Experimental Allergy 2008-07-09

Journal Article Risk factors for atopic dermatitis in New Zealand children at 3·5 years of age Get access D.J. Purvis, Purvis Department Paediatrics, School Population Health Search other works by this author on: Oxford Academic Google Scholar J.M.D. Thompson, Thompson P.M. Clark, Clark E. Robinson, Robinson P.N. Black, Black Medicine C.J. Wild, Wild Statistics, University Auckland, Private Bag 92019, E.A. Mitchell A. Mitchell. E‐mail: e.mitchell@auckland.ac.nz British Dermatology, Volume...

10.1111/j.1365-2133.2005.06540.x article EN British Journal of Dermatology 2005-04-01

Objective Our aim was to replicate and extend the recently found association between acetaminophen use during pregnancy ADHD symptoms in school-age children. Methods Participants were members of Auckland Birthweight Collaborative Study, a longitudinal study 871 infants European descent sampled disproportionately for small gestational age. Drug (acetaminophen, aspirin, antacids, antibiotics) analysed relation behavioural difficulties measured by parent report at age 7 both parent-...

10.1371/journal.pone.0108210 article EN cc-by PLoS ONE 2014-09-24

Summary Background Using a double blind randomized placebo‐controlled trial ( A ustralian N ew Z ealand C linical T rials R egistry: ACTRN 12607000518460), we have shown that in high risk birth cohort, maternal supplementation from 35 weeks gestation until 6 months if breastfeeding and infant 2 years with Lactobacillus rhamnosus HN 001 001) (6 × 10 9 cfu/day) halved the cumulative prevalence of eczema by age years. Bifidobacterium animalis subsp lactis 019 019) (9 had no effect. Objective...

10.1111/j.1365-2222.2012.03975.x article EN Clinical & Experimental Allergy 2012-02-07

Objective To investigate whether reported fast-food consumption over the previous year is associated with higher childhood or adolescent body mass index (BMI). Design Secondary analysis from a multicentre, multicountry cross-sectional study (International Study of Asthma and Allergies in Children (ISAAC) Phase Three). Subjects methods Parents/guardians children aged 6–7 completed questionnaires which included questions about their children's asthma allergies, consumption, height weight....

10.1136/bmjopen-2014-005813 article EN cc-by-nc BMJ Open 2014-12-01

OBJECTIVE: To determine the vitamin D dose necessary to achieve serum 25-hydroxyvitamin (25(OH)D) concentration ≥20 ng/mL during infancy. METHODS: A randomized, double-blind, placebo-controlled trial in New Zealand. Pregnant mothers, from 27 weeks’ gestation birth, and then their infants, birth age 6 months, were randomly assigned 1 of 3 mother/infant groups: placebo/placebo, D3 1000/400 IU, or 2000/800 IU. Serum 25(OH)D calcium concentrations measured at enrollment, 36 gestation, cord...

10.1542/peds.2013-2602 article EN PEDIATRICS 2013-12-17

There may be a link between disruption to the gut microbiota in early life and later neurocognitive outcomes. We hypothesised that antibiotic use is associated with detrimental effect on outcomes.Eight hundred seventy-one European mothers their children enrolled Auckland Birthweight Collaborative Study at birth. Information during first year of 12 months three-and-a-half years age was gathered via maternal interview. Intelligence test scores measures behavioural difficulties were obtained...

10.1111/apa.13613 article EN Acta Paediatrica 2016-10-12
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