A5024541959- Amyotrophic Lateral Sclerosis Research
- Biocrusts and Microbial Ecology
- Protist diversity and phylogeny
- Prion Diseases and Protein Misfolding
- Neurological diseases and metabolism
- Marine and coastal plant biology
- Child and Animal Learning Development
- Autism Spectrum Disorder Research
- Parkinson's Disease Mechanisms and Treatments
- Behavioral and Psychological Studies
- Biochemical Acid Research Studies
- Microbial Community Ecology and Physiology
Hebrew University of Jerusalem
2023-2024
King's College London
2014-2016
Abstract Zygnematophyceae are the algal sisters of land plants. Here we sequenced four genomes filamentous Zygnematophyceae, including chromosome-scale assemblies for three strains Zygnema circumcarinatum . We inferred traits in ancestor and plants that might have ushered conquest by plants: expanded genes signaling cascades, environmental response, multicellular growth. share all major enzymes cell wall synthesis remodifications, gene gains shaped this toolkit. Co-expression network...
ABSTRACT The filamentous and unicellular algae of the class Zygnematophyceae are closest algal relatives land plants. Inferring properties last common ancestor shared by these plants allows us to identify decisive traits that enabled conquest We sequenced four genomes (three strains Zygnema circumcarinatum one strain Z. cylindricum ) generated chromosome-scale assemblies for all emerging model system . Comparative genomic analyses reveal expanded genes signaling cascades, environmental...
Amyotrophic lateral sclerosis (ALS) is a progressive and usually fatal neurodegenerative disease. Survival from diagnosis varies considerably. Several prognostic factors are known, including site of onset (bulbar or limb), age at symptom onset, delay to the use riluzole non-invasive ventilation (NIV). Clinicians patients would benefit practical way using these provide an individualised prognosis.575 consecutive with incident ALS population-based registry in South-East England register for...
AbstractAmyotrophic lateral sclerosis (ALS, motor neuron disease) is a neurodegenerative disorder of neurons leading to paralysis and eventual death by respiratory failure. Median survival 2–3 years. Susceptibility genes, environmental triggers disease related prognostic factors have been established, but effects on are yet be investigated. We analysed in the South-East England ALS register (SEALS register). Kaplan-Meier Cox regression analyses were used investigate London, coastal rural...
Individuals with autism spectrum disorder (ASD) and low intellectual/language abilities are often omitted from experimental studies because of the challenges testing these individuals. It is vital to develop appropriate accessible tasks so that this significant part not neglected. The theory mind (ToM) has been extensively assessed in ASD, predominantly relatively high-functioning individuals reasonable language skills. This study aims assess ToM a sample 132 participants intellectual...