A5021182948- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Fungal Infections and Studies
- Vibrio bacteria research studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Salmonella and Campylobacter epidemiology
- Nosocomial Infections in ICU
- Antimicrobial Resistance in Staphylococcus
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Pneumocystis jirovecii pneumonia detection and treatment
- Urinary Tract Infections Management
- Global Health Care Issues
Pfizer (United States)
2020-2025
This article is the first to review published reports on prevalence of multidrug-resistant (MDR) gram-negative infections in Egypt and gain insights into antimicrobial resistance (AMR) surveillance susceptibility testing capabilities Egyptian medical centers.A literature online survey were conducted.The reported high extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (19-85.24% E. coli, 10-87% K. pneumoniae), carbapenem-resistant (35-100% pneumoniae 13.8-100% coli),...
Abstract Background Complicated urinary tract infections (cUTIs) arise in patients with structural or functional abnormalities of the genitourinary those nonurogenital comorbidities. cUTIs are common older catheterized persons and can be associated high healthcare resource utilization (HCRU). We conducted a systematic literature review to understand economic burden cUTI. Methods A was using PubMed, Embase, Cochrane, EconLit databases identify observational studies evaluating cUTI, including...
Abstract Objectives To determine the in vitro susceptibility of Enterobacterales (n = 5457) and Pseudomonas aeruginosa 1949) isolated from hospitalized patients Africa (three countries) Middle East (five 2018–20 to a panel 11 antimicrobials identify β-lactamase/carbapenemase genes isolates with meropenem-non-susceptible and/or ceftazidime/avibactam-resistant phenotypes. Methods CLSI broth microdilution testing generated MICs that were interpreted using (2021) breakpoints....
ObjectivesCommunity-acquired (CAIs) and healthcare-associated (HAIs) infections are associated with significant morbidity mortality. Data related to the epidemiology of these in Middle East is scarce. The aim this study estimate prevalence antimicrobial use acute hospital setting region.MethodsA multicentre Point-Prevalence Survey was conducted seven Eastern countries: Egypt, Kingdom Saudi Arabia, United Arab Emirates, Lebanon, Oman, Kuwait Bahrain. were collected by infection control...
Abstract Objectives To assess the in vitro activity of ceftazidime/avibactam against a recent, 2015–18, collection clinical isolates Gram-negative bacilli from Middle Eastern and African countries with focus on ICUs MDR difficult-to-treat resistance (DTR) phenotypes. Methods Antimicrobial susceptibility testing 4608 Enterobacterales (997 ICU patients) 1358 Pseudomonas aeruginosa (374 was performed by CLSI broth microdilution methodology central laboratory. MICs were interpreted using both...
To report antimicrobial susceptibility testing surveillance data for ceftaroline and comparative agents from the AWARE global programme bacterial pathogens causing skin soft tissue infections (SSTIs) lower respiratory (RTIs) in Middle East African countries 2015 to 2018. Pathogens were identified by MALDI-TOF/MS. Antimicrobial was performed using Clinical Laboratory Standards Institute (CLSI) broth microdilution method. MICs interpreted both CLSI (M100, 2020) European Committee on...
Background: Invasive fungal infections (IFIs) in immunocompromised patients are associated with high mortality and treatment costs. Identifying appropriate, cost-effective strategies is crucial to reduce the burden of IFIs. This economic assessment compared for treating Algeria Egypt.Methods: We developed a decision analytic model incorporating clinical cost inputs diagnostic-driven (DD) standard empirical (SE) strategy. Costs outcomes were used calculate incremental cost-effectiveness...
Abstract Background Enterobacterales remain the most common cause of UTIs and are associated with increased rates resistance to commonly prescribed antibiotics. The objective this study is describe prevalence frequency ESBL-producing (ESBL-E) causing AP, as well current antimicrobial these pathogens.Figure 1.Percentage E. Coli isolates resistant antibiotics in US. Red dashed line separates studies only from including all isolates. AP = acute pyelonephritis; cUTI complicated urinary tract...