A5090349087- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Treatment of Major Depression
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Neural dynamics and brain function
MIND Research Institute
2016-2019
Cornell University
2016-2019
Weill Cornell Medicine
2019
The neurobiological mechanisms underlying the induction and remission of depressive episodes over time are not well understood. Through repeated longitudinal imaging medial prefrontal microcircuits in living brain, we found that spinogenesis plays a critical role sustaining specific antidepressant behavioral effects maintaining long-term remission. Depression-related behavior was associated with targeted, branch-specific elimination postsynaptic dendritic spines on projection neurons....