A5016268494- Mesenchymal stem cell research
- Pluripotent Stem Cells Research
- Biomedical Ethics and Regulation
- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Diversity and Career in Medicine
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Sarcoma Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Renal cell carcinoma treatment
- COVID-19 and healthcare impacts
- Vascular Tumors and Angiosarcomas
- Surgical Simulation and Training
- Tissue Engineering and Regenerative Medicine
Northwestern University
2023-2024
Universidade Federal de Minas Gerais
2020-2024
Yale University
2018-2020
We have previously shown that bone marrow-derived mesenchymal stem cells (BMSC) accelerate wound healing in a diabetic mouse model. In this study, we hypothesized adipose tissue-derived (ADSC), of greater translational potential to human therapy, improve similar extent as BMSC. vitro, the characterization and function murine ADSC BMSC well nondiabetic were evaluated by flow cytometry, cell viability, VEGF expression. vivo, biomimetic collagen scaffolds containing or used treat splinted...
The application of human-induced pluripotent stem cells (hiPSCs) to generate vascular smooth muscle (hiPSC-VSMCs) in abundance is a promising strategy for regeneration. While hiPSC-VSMCs have already been utilized tissue-engineered grafts and disease modeling, there lack investigations exploring their therapeutic secretory factors. objective this manuscript was understand how the biophysical property collagen-based scaffold dictates changes function while developing hiPSC-VSMC-based therapy...
INTRODUCTIONWith advances in current therapies, more patients are currently surgical candidates for oncologic resections that were previously deemed unresectable due to vascular invasion. We analyzed our institution's outcomes of undergoing oncovascular resection truncal malignancies with invasion identify factors associated reconstruction complications and recurrence.METHODSA retrospective chart review all adult between January 1, 2002 June 2022 who underwent a neoplasm at Northwestern...
Despite scientific advances, vascular diseases are responsible for one third of deaths. Understanding the biology stem cells and cell therapy can mean an important advance in reducing this mortality.