A bistable switch from a low pH (unreacted “off”) state to high (reacted “on”) was obtained in enzyme-loaded gel beads response supra-threshold substrate concentrations.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTToward a systematic determination of complex reaction mechanismsTim Chevalier, Igor Schreiber, and John RossCite this: J. Phys. Chem. 1993, 97, 26, 6776–6787Publication Date (Print):July 1, 1993Publication History Published online1 May 2002Published inissue 1 July 1993https://pubs.acs.org/doi/10.1021/j100128a006https://doi.org/10.1021/j100128a006research-articleACS PublicationsRequest reuse permissionsArticle Views226Altmetric-Citations60LEARN...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDynamics of forced excitable and oscillatory chemical reaction systemsM. Dolnik, J. Finkeova, I. Schreiber, M. MarekCite this: Phys. Chem. 1989, 93, 7, 2764–2774Publication Date (Print):April 1, 1989Publication History Published online1 May 2002Published inissue 1 April 1989https://pubs.acs.org/doi/10.1021/j100344a015https://doi.org/10.1021/j100344a015research-articleACS PublicationsRequest reuse permissionsArticle...

Experiments with oxidation circular waves in a quasi-two-dimensional Belousov−Zhabotinsky reaction medium subject to an external dc electric field reveal variety of wave dynamics scenarios involving splitting, reversal, annihilation, and complex pattern formation. We also investigate effects initial concentration reactants on the find marked sensitivity related excitability medium. Two different variants Oregonator model are shown have common dimensionless representation providing conversion...

We examine experimentally a chemical system in flow-through stirred reactor, which is known to provide large-amplitude oscillations of the pH value. By systematic variation flow rate, we find that displays hysteresis between steady state and oscillations, more interestingly, transition chaos involving mixed-mode oscillations. The basic pattern measured regime includes large-scale peak followed by series on much smaller scale, are usually highly irregular variable duration. bifurcation...

We investigate the categorization of two or more proposed reaction mechanisms for each following oscillatory enzymatic reactions: (1) peroxidase−oxidase reaction; (2) glycolytic oscillations; (3) oscillations cyclic AMP in slime mold cells; (4) pH (5) calcium spiking cytosol. use prior work stoichiometric network analysis and reactions to identify mechanism essential nonessential species, specific role connectivity including identification leading instabilities, category. For model, we...

The reaction between tetrathionate and hydrogen peroxide forms an important part of several pH oscillators based on the oxidation thiosulfate. kinetics this were examined in a batch reactor by measurement initial values range from 8 to 10.5. Experimental data evaluated method rates combined with assumption instantaneously equilibrated acid−base reactions. rate-determining step was found be first order respect tetrathionate, peroxide, OH- ions value rate constant k = (1.50 ± 0.03) × 102 (M2...

Prompted by the recent growing evidence of oscillatory behavior involving MAPK cascades we present a systematic approach analyzing models and elucidating nature biochemical oscillations based on reaction network theory. In particular, formulate minimal biochemically consistent mass action subnetwork Huang-Ferrell model signalling that provides an response when parameter controlling activation top-tier kinase is varied. Such dynamics are either intertwined with or separated from earlier found...

We study a model system of three diffusively coupled reaction cells arranged in linear array that display Turing patterns with special focus on the case equal coupling strength for all components. As suitable we consider two-variable core glycolysis. Using numerical continuation and bifurcation techniques analyze dependence system's steady states varying rate coefficient recycling step while coefficients inhibitor activator are fixed set at ratios 100:1, 1:1, 4:5. show stable occur but, as...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Reaction Mechanism for the Oscillatory Peroxidase-Oxidase and Comparison with ExperimentsYu-Fen Hung, Igor Schreiber, John RossCite this: J. Phys. Chem. 1995, 99, 7, 1980–1987Publication Date (Print):February 1, 1995Publication History Published online1 May 2002Published inissue 1 February 1995https://pubs.acs.org/doi/10.1021/j100007a031https://doi.org/10.1021/j100007a031research-articleACS PublicationsRequest reuse permissionsArticle...

We employ numerical techniques for solving time-dependent full Poisson-Nernst-Planck (PNP) equations in 2D to analyze transient behavior of a simple ion channel subject sudden electric potential jump across the membrane (voltage clamp). Calculated spatiotemporal profiles ionic concentrations and show that two principal exponential processes can be distinguished electrodiffusion kinetics, agreement with original Planck's predictions. The initial fast process corresponds dielectric relaxation,...

The classification/categorization of oscillatory chemical reactions and the determination connectivity species in a reaction mechanism can be deduced from several experiments. In this article we show same for bifurcation diagrams. We construct such diagrams skeletal models each known categories; these are distinct used classification essential oscillations categorization reactions. closely related to concentration shift matrix. Prototypes categories 1B 1C extended by adding nonessential...

We present results of experiments focused on emergent and cooperative dynamics in a system two coupled flow-through stirred reaction cells with diffusion-like mass exchange strongly nonlinear chemical between hydrogen peroxide thiosulphate catalysed by cupric ions diluted solution sulphuric acid. Due to complex mechanism, which crucial role is played and/or hydroxide ions, single cell entail multiple stationary states, excitability oscillations conveniently indicated measuring pH. When...