- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Viral Infections and Vectors
- Insect and Pesticide Research
- Zoonotic diseases and public health
- Influenza Virus Research Studies
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Viral gastroenteritis research and epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Yeasts and Rust Fungi Studies
- Hepatitis B Virus Studies
- Health Policy Implementation Science
- COVID-19 Impact on Reproduction
- Natural Language Processing Techniques
- Horticultural and Viticultural Research
- Health disparities and outcomes
- Topic Modeling
- COVID-19 epidemiological studies
- Biomedical Text Mining and Ontologies
- Global Public Health Policies and Epidemiology
- Fermentation and Sensory Analysis
Robert Koch Institute
2021-2024
Charité - Universitätsmedizin Berlin
2024
Humboldt-Universität zu Berlin
2024
Freie Universität Berlin
2024
Tick-borne encephalitis (TBE) vaccination coverage remains low in Germany. Our case-control study (2018-2020) aimed to examine reasons for vaccine uptake, effectiveness (VE), and breakthrough infections (VBIs). Telephone interviews (581 cases, 975 matched controls) covered vaccinations, barriers, confounders identified with directed acyclic graphs. Multivariable logistic regression determined VE as 1-odds ratio 95% confidence intervals (CI). We additionally calculated the Screening method...
Despite being vaccine-preventable, tick-borne encephalitis (TBE) continues to cause considerable morbidity in Germany. Limited insight into potentially debilitating consequences of TBE may partially underly low (~ 20%) vaccine uptake. We aimed systematically assess sequelae and other consequences.Routinely notified patients from 2018 2020 Southern Germany were invited telephone interviews acutely again after 18 months. Duration acute symptoms was prospectively assessed. Recovery defined as...
National immunization technical advisory groups (NITAGs) develop immunization-related recommendations and assist policy-makers in making evidence informed decisions. Systematic reviews (SRs) that summarize the available on a specific topic are valuable source of development such recommendations. However, conducting SRs requires significant human, time, financial resources, which many NITAGs lack. Given already exist for topics, to prevent duplication overlap reviews, more practical approach...
During 2021 and 2023, a team of researchers at the Robert Koch Institute (RKI) partnering institutions conducted two living systematic reviews (LSRs) on effectiveness COVID-19 vaccines in different age groups to inform recommendations Standing Committee Vaccination Germany (Ständige Impfkommission, STIKO). Based our experience from realization these LSRs, we developed certain criteria assess needs feasibility conducting LSRs. Combining with previously established criteria, following set...
Tick-borne encephalitis (TBE) is a growing public health problem with increasing incidence and expanding risk areas. Improved prevention requires better understanding of the spatial distribution ecological determinants TBE transmission. However, map at sub-district level still missing for Germany. We investigated geo-spatial characteristics 567 self-reported places probable infection (POI) from 359 cases notified in 2018-2020 study area Bavaria Baden-Wuerttemberg, compared to 41 confirmed...
In Germany, tick-borne encephalitis (TBE) infections mainly occur in southern regions. Despite recent increases incidence, TBE vaccination coverage remains low, necessitating additional preventive strategies against TBE. Our case-control study Southern Germany from 2018 to 2020 mapped knowledge/application of tick-protective and identified risk factors. We calculated odds ratios (OR), with 95% confidence intervals (CI). interviewed 581 cases 975 matched controls. Most participants recalled...
Abstract Background The SARS-CoV-2 Omicron variant is currently the dominant globally. This 3 rd interim analysis of a living systematic review summarizes evidence on COVID-19 vaccine effectiveness (VE) and duration protection against Omicron. Methods We systematically searched literature for controlled studies evaluating vaccines approved in European Union up to 14/01/2022, complemented by hand-searches websites metasearch engines 11/02/2022. considered following comparisons: full primary...
Background: This umbrella review summarises the global evidence on risk of severe COVID-19 outcomes in patients with pre-existing health conditions. Methods: Systematic reviews (SRs) were identified PubMed, Embase/Medline, and seven pre-print servers until December 11, 2020. Risk estimates (odds ratio (OR), hazard (HR), relative (RR)) for hospitalisation, intensive care unit admission, intubation, death extracted from primary studies. Meta-analyses performed stratified by regions World...
Entity recognition from semi or unstructured systematic reviews is one of the most essential processes for evidence-based decision-making systems. The task involves collecting information diverse studies concerning PICO (Population, Intervention, Comparison, and Outcomes) elements with additional domain-related using named entity (NER) as it fundamental extracting structured data. In this study, we create an adapted immunization-related dataset evaluate its performance in extraction relevant...