A5077042501- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Insect and Pesticide Research
- COVID-19 and healthcare impacts
- Zoonotic diseases and public health
- COVID-19 Impact on Reproduction
- Global Public Health Policies and Epidemiology
- Healthcare cost, quality, practices
- Health disparities and outcomes
Robert Koch Institute
2021-2024
Charité - Universitätsmedizin Berlin
2022-2024
BackgroundTick-borne encephalitis (TBE) is a vaccine-preventable disease involving the central nervous system. TBE became notifiable on EU/EEA level in 2012.AimWe aimed to provide an updated epidemiological assessment of EU/EEA, focusing spatiotemporal changes.MethodsWe performed descriptive analysis case characteristics, time and location using data human cases reported by countries European Centre for Disease Prevention Control with onset 2012-2020. We analysed at national, subnational...
Tick-borne encephalitis (TBE) vaccination coverage remains low in Germany. Our case-control study (2018-2020) aimed to examine reasons for vaccine uptake, effectiveness (VE), and breakthrough infections (VBIs). Telephone interviews (581 cases, 975 matched controls) covered vaccinations, barriers, confounders identified with directed acyclic graphs. Multivariable logistic regression determined VE as 1-odds ratio 95% confidence intervals (CI). We additionally calculated the Screening method...
Despite being vaccine-preventable, tick-borne encephalitis (TBE) continues to cause considerable morbidity in Germany. Limited insight into potentially debilitating consequences of TBE may partially underly low (~ 20%) vaccine uptake. We aimed systematically assess sequelae and other consequences.Routinely notified patients from 2018 2020 Southern Germany were invited telephone interviews acutely again after 18 months. Duration acute symptoms was prospectively assessed. Recovery defined as...
Endemic and imported vector- rodent-borne infectious agents can be linked to high morbidity mortality. Therefore, human diseases the effects of climate change are important public health issues.
Tick-borne encephalitis (TBE) is a growing public health problem with increasing incidence and expanding risk areas. Improved prevention requires better understanding of the spatial distribution ecological determinants TBE transmission. However, map at sub-district level still missing for Germany. We investigated geo-spatial characteristics 567 self-reported places probable infection (POI) from 359 cases notified in 2018-2020 study area Bavaria Baden-Wuerttemberg, compared to 41 confirmed...
In Germany, tick-borne encephalitis (TBE) infections mainly occur in southern regions. Despite recent increases incidence, TBE vaccination coverage remains low, necessitating additional preventive strategies against TBE. Our case-control study Southern Germany from 2018 to 2020 mapped knowledge/application of tick-protective and identified risk factors. We calculated odds ratios (OR), with 95% confidence intervals (CI). interviewed 581 cases 975 matched controls. Most participants recalled...
Background: This umbrella review summarises the global evidence on risk of severe COVID-19 outcomes in patients with pre-existing health conditions. Methods: Systematic reviews (SRs) were identified PubMed, Embase/Medline, and seven pre-print servers until December 11, 2020. Risk estimates (odds ratio (OR), hazard (HR), relative (RR)) for hospitalisation, intensive care unit admission, intubation, death extracted from primary studies. Meta-analyses performed stratified by regions World...