A5069549803- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Dermatological diseases and infestations
- Mosquito-borne diseases and control
- Yersinia bacterium, plague, ectoparasites research
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Biosensors and Analytical Detection
- Syphilis Diagnosis and Treatment
- Toxin Mechanisms and Immunotoxins
- Zoonotic diseases and public health
- Listeria monocytogenes in Food Safety
- Rabies epidemiology and control
- Reproductive tract infections research
- Bartonella species infections research
- Animal Ecology and Behavior Studies
- Insect symbiosis and bacterial influences
- Transgenic Plants and Applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medical Device Sterilization and Disinfection
- Exercise and Physiological Responses
- Animal Disease Management and Epidemiology
- Viral Infections and Outbreaks Research
- Marine and fisheries research
Austrian Agency for Health and Food Safety
2022-2025
Medical University of Vienna
2013-2023
European Society of Clinical Microbiology and Infectious Diseases
2022
Institute of Medical Microbiology and Hygiene
2019
BackgroundTick-borne encephalitis (TBE) is a vaccine-preventable disease involving the central nervous system. TBE became notifiable on EU/EEA level in 2012.AimWe aimed to provide an updated epidemiological assessment of EU/EEA, focusing spatiotemporal changes.MethodsWe performed descriptive analysis case characteristics, time and location using data human cases reported by countries European Centre for Disease Prevention Control with onset 2012-2020. We analysed at national, subnational...
Abstract The aim of this prospective study was to assess the risk for tickborne infections after a tick bite. A total 489 persons bitten by 1,295 ticks were assessed occurrence with Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum, Rickettsia spp., Babesia Candidatus Neoehrlichia mikurensis, and relapsing fever borreliae. B. s.l. infection found in 25 (5.1%) participants, whom 15 had erythema migrans. Eleven (2.3%) participants positive PCR N. mikurensis. One asymptomatic...
We report on a non-indigenous adult Hyalomma marginatum tick in Austria carrying the human pathogenic Rickettsia aeschlimannii; presumably introduced as nymph via migratory birds and completed moulting within same year. It was negative for Crimean-Congo haemorrhagic fever virus, but finding of R. aeschlimannii represents potential threat humans due to its zoonotic character. Awareness invasive species carried pathogens should be improved central northern Europe.
Abstract We report a human case of Borrelia miyamotoi infection diagnosed in Austria. Spirochetes were detected Giemsa-stained blood smears. The presence B. the patient’s was confirmed by PCR, and phylogenetic analysis identified an with strain from Europe.
Abstract Infection of humans with Chlamydia trachomatis , a bacterial pathogen unique intracellular replication cycle, may cause variety clinical manifestations. These are linked to various serovars the pathogen; trachoma A-C, oculogenital infections D-K, and lymphogranuloma venereum L1-L3. Nineteen known as human pathogens. The aim study was determine 401 C. DNA positive extracts from original specimens patients in Austria including cervical urethral swabs, urine, genital secretions...
During cutaneous tick attachment, the feeding cavity becomes a site of transmission for salivary compounds and tick-borne pathogens. However, immunological consequences human skin remain unclear. Here, we assessed blood samples upon bite developed explant model mimicking Ixodes ricinus bites pathogen infection. Following observed rapidly occurring patterns immunomodulation, including increases in neutrophils B T cells. cells upregulated tissue residency markers, while lymphocytic cytokine...
The relapsing fever group Borrelia miyamotoi is an emerging tick-borne pathogen. Diagnosis of infection currently mainly based on serological methods detecting antibodies against B. glycerophosphodiester phosphodiesterase (GlpQ). Here, we scrutinized the reliability GlpQ as a diagnostic marker and compared seroprevalence in different study populations by applying various immunoblotting methods. Antibodies were detected sera 7/53 hunters 1/11 Lyme neuroborreliosis patients. Furthermore, 17/74...
The aim of the study was to investigate etiology persistent IgM antibodies against Borrelia burgdorferi sensu lato (sl) and analyze their association with nonspecific symptoms. group comprised individuals in absence IgG. relation between ELISA values time elapsed since past erythema migrans (EM) analyzed. Previous antibiotic treatments were assessed. symptoms evaluated statistically. Specificity for outer surface protein C (OspC) B. sl examined by immunoblotting. Further, we investigated...
The aim of this study was to determine whether patients with antibodies against Borrelia burgdorferi sensu lato or who report a history erythema migrans (EM) tick bite are more likely have non-specific symptoms such as musculoskeletal pain, fatigue, sensory disorder, and headache. group comprised 423 subjects tested for B. between July 2012 December 2014 because suspicion Lyme borreliosis (LB). Of these, 285 were females (67%) 138 males (33%); the median age 53 years (range, 7-89 years)....
Rickettsia spp. are the second most common pathogens detected in Ixodes ricinus ticks Austria after Borrelia burgdorferi sensu lato. Species belonging to spotted fever group (SFG) causative agents for tick-borne rickettsiosis across world. So far, only four SFG were Austria, namely R. helvetica, raoultii, monacensis and slovaca. Here, we describe identification of a new species an I. tick. Sequencing various rickettsial genes revealed nucleotide sequence similarity 99.6%, 98.5%, 97.3% 98.5%...
Abstract Background Identification of mosquitoes greatly relies on morphological specification. Since some species cannot be distinguished reliably by methods, it is important to incorporate molecular techniques into the diagnostic pipeline. DNA barcoding using Sanger sequencing currently widely used for identification mosquito species. However, this method does not allow detection multiple in one sample, which would when analysing eggs. Detection container breeding Aedes typically performed...
Hyalomma marginatum is an invasive tick species capable of transmitting pathogens that cause severe diseases such as Crimean-Congo hemorrhagic fever. In Austria, H. occurs sporadically, and migratory birds are believed to bring from distant regions. We report several incidents imported by travelers in private cars Croatia Austria. One was positive for Rickettsia aeschlimannii. Tourist traffic may play a significant role the northward expansion this aside introduction birds.
Abstract Introduction Tick-borne encephalitis (TBE), caused by tick-borne virus (TBEV), is a zoonotic disease that can cause severe neurological symptoms. As we observed an increasing number of reported TBE human cases in Europe, developed spatio-temporal predictive model to infer the year-to-year probability occurrence across Europe at regional and municipal administrative levels. Methods We derived distribution (NUTS-3) level during period 2017-2022, using data provided European...
Abstract Background The diagnosis of human anaplasmosis remains elusive and is probably often missed. This case report highlights the efficacy molecular diagnostic techniques. Case presentation We would like to a 74-year-old man who was admitted hospital because high fever, marked chills, transient diplopic images vertigo, 6 weeks after multiple tick bites. laboratory results showed mild anemia, thrombocytopenia leukopenia moderately elevated C-reactive protein. initial serology seemed...
Tularemia is increasing in Austria. We report Francisella tularensis subspecies holarctica isolated from 3 patients who had been bitten by arthropods. Next-generation sequencing showed substantial isolate similarity. Clinicians should consider bloodstream F. infections for with signs/symptoms of ulceroglandular tularemia, and surveillance potential vectors be intensified.