A5027499579- Vector-borne infectious diseases
- Viral Infections and Vectors
- Antibiotic Resistance in Bacteria
- Mosquito-borne diseases and control
- SARS-CoV-2 detection and testing
- Bacterial Identification and Susceptibility Testing
- SARS-CoV-2 and COVID-19 Research
- Vector-Borne Animal Diseases
- Infective Endocarditis Diagnosis and Management
- Actinomycetales infections and treatment
- Syphilis Diagnosis and Treatment
- Infections and bacterial resistance
- Insect and Pesticide Research
- Bacterial biofilms and quorum sensing
- Animal Virus Infections Studies
- Reproductive tract infections research
- HIV/AIDS oral health manifestations
- Enterobacteriaceae and Cronobacter Research
- Escherichia coli research studies
- Herpesvirus Infections and Treatments
- Genomics and Phylogenetic Studies
- Biosensors and Analytical Detection
- Yersinia bacterium, plague, ectoparasites research
- Bartonella species infections research
- Insect symbiosis and bacterial influences
ADMED (Switzerland)
2016-2025
Laboratoire National de Référence
2018-2024
University of Fribourg
2024
European Society of Clinical Microbiology and Infectious Diseases
2022
bioMérieux (France)
2021
Spiez Laboratory
2018-2020
Instituto de Medicina Tropical “Pedro Kourí”
2012
International Museum of Horology
2006
University of Neuchâtel
1989-2000
University of Maryland, Baltimore
1995
The new SARS-CoV-2 Omicron variant (B.1.1.529) has been recently declared a Variant of Concern due to series important mutations in the viral spike protein and especially receptor-binding domain. While investigations into spread this are ongoing, first cases have detected Switzerland. Important questions raised: (1) Will PCR assays commonly used detect still work for variant? (2) Can specific features, e.g. S-gene dropout, be identify potential samples? In minireview we provide current...
Following the Swiss Federal Office of Public Health (FOPH) authorization rapid antigen test (RAT), we implemented use RAT in emergency ward our university hospital for patients’ cohorting. triaging association with RT-PCR allowed us to promptly isolate positive patients and save resources. Among 532 patients, overall sensitivities were 48.3% Exdia 41.2% Standard Q®, PanbioTM BD Veritor™. All RATs exhibited specificity above 99%. Sensitivity increased 74.6%, 66.2%, 66.2% 64.8% Exdia,...
During an eight week period in spring 2005, 10 cases of listeriosis were reported a small area northwest Switzerland (150,000 inhabitants). Eight older immunocompromised patients who became ill with bacteraemia (three deaths), and two pregnant women had septic abortion. All due to serotype 1/2a isolate one pulsovars found by PFGE. Patient interviews quickly revealed that locally made distributed soft cheese (known as 'tomme') was the food source responsible for outbreak. Samples this cheese,...
Rejection (nomen rejiciendum) of the name Borreliella and all new combinations therein is being requested on grounds risk to human health patient safety (Principle 1, subprinciple 2 Rule 56a) violation aim for stability names, avoid useless creation names 1 3) that should not be changed without sufficient reason 9 International Code Nomenclature Prokaryotes).
Abstract This study compared standard of care testing (SOC) to BioFire® FilmArray® Pneumonia plus Panel (PN ). PN detects 15 bacteria with semiquantitative log bin values, 7 antibiotic resistance markers, three atypical (AB), and eight viral classes directly from bronchoalveolar lavage-like specimens (BLS) sputum-like (SLS). Fifty-two laboratories 13 European countries Israel tested 1234 BLS 1242 SLS SOC. Detection rates number pathogens/samples were for pathogens. values SOC quantities...
The rapid spread of the SARS-CoV-2 lineages B.1.1.7 (N501Y.V1) throughout UK, B.1.351 (N501Y.V2) in South Africa, and P.1 (B.1.1.28.1; N501Y.V3) Brazil has led to definition variants concern (VoCs) recommendations for lineage specific surveillance. In Switzerland, during last weeks December 2020, we established a nationwide screening protocol across multiple laboratories, focusing first on epidemiological microbiological definitions. January 2021, validated implemented an N501Y-specific PCR...
The occurrence of metallo-beta-lactamase-producing Pseudomonas aeruginosa (MBL-PA) isolates is increasing globally, including in Switzerland. aim this study was to characterise, phenotypically and genotypically, the MBL-PA submitted Swiss National Reference Center for Emerging Antibiotic Resistance (NARA) reference laboratory over a 12-month period from July 2022 2023.
ObjectivesTo assess the in vitro susceptibility of Actinobaculum schaalii to 12 antimicrobial agents as well dissect genetic basis fluoroquinolone resistance.
Studies on the antimicrobial susceptibility profile of anaerobic bacteria are underrepresented in literature. Within this study we aim to give an extensive overview differences profiles between different European and surrounding countries.Minimal inhibitory concentration (MIC) data antibiotics were collected from 10 participating laboratories, representing equal number countries. All MIC's determined using Etest, according protocol used by laboratory. Anaerobic genera represented at least...
Real-time RT-PCR remains a gold standard in the detection of various viral diseases. In coronavirus 2019 pandemic, multiple RT-PCR–based tests were developed to screen for infection. As an emergency response increasing testing demand, we established severe acute respiratory syndrome 2 (SARS-CoV-2) PCR diagnostics platform which compared different commercial and in-house protocols. Four commercial, one customized, protocols evaluated with 92 SARS-CoV-2–positive SARS-CoV-2–negative samples....
In the last 10 years, an increase in tularemia cases has been observed both humans and animals Switzerland. these, infection with Francisella tularensis, causative agent of zoonotic disease tularemia, can occur through arthropod vectors or contact to infected exposure contaminated environmental sources. Currently, we are only able postulate potential aetiologies: (i) behavioral changes more endemic habitats vectors; (ii) increased rate ticks; (iii) increasing number geographical regions tick...
Tick-borne encephalitis virus (TBEV) infection can manifest as disease of variable severity, ranging from subclinical to severe with neurological involvement and potentially fatal outcome. Although TBE is recognized a major public health problem in Europe, the true burden underestimated. Here, we investigated TBEV-specific antibody prevalence, incidence, seroreversion decline rates prospective Swiss healthcare worker (HCW) cohort. We screened serum samples 1444 HCWs between June October...
Matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) is a widely used method for bacterial species identification. Incomplete databases and spectral quality (MSQ) still represent major challenges. Important proxies MSQ are the number detected marker masses, reproducibility, measurement precision. We aimed to assess MSQs across diagnostic laboratories potential simple workflow adaptations improve it.For baseline assessment, 47 diverse strains, which...
ABSTRACT We report a case of Pasteurella multocida meningitis in 1-month-old baby exposed to close contact with two dogs and cat but without any known history injury by these animals. 16S rRNA gene sequencing the isolate from allowed identification at subspecies level pointed as possible source infection. Molecular typing isolates animals, baby, unrelated animals clearly confirmed that harbored same P. subsp. septica strain on its tonsils one isolated cerebrospinal fluid baby. This stresses...