A5038005132- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Malaria Research and Control
- Parasite Biology and Host Interactions
- Parasitic Diseases Research and Treatment
- Vector-Borne Animal Diseases
- Parasites and Host Interactions
- Bird parasitology and diseases
- Insect symbiosis and bacterial influences
- Helminth infection and control
- Dengue and Mosquito Control Research
- Bartonella species infections research
- Insect and Pesticide Research
- Trypanosoma species research and implications
- Mollusks and Parasites Studies
- Crystallization and Solubility Studies
- Zoonotic diseases and public health
- Insects and Parasite Interactions
- X-ray Diffraction in Crystallography
- Computational Drug Discovery Methods
- Study of Mite Species
- Forensic Entomology and Diptera Studies
- Dermatological diseases and infestations
- Research on Leishmaniasis Studies
University of Veterinary Medicine Vienna
2016-2025
Johns Hopkins Medicine
2025
Johns Hopkins University
2022-2025
Institute of Parasitology
2022-2024
Wellesley College
2022
University of Veterinary Medicine
2013-2022
Shanghai Municipal Center For Disease Control Prevention
2019
Medical University of Vienna
2009-2018
University of Veterinary Sciences Brno
2018
University of Bangui
2018
Recent gains in reducing the global burden of malaria are threatened by emergence Plasmodium falciparum resistance to artemisinins. The discovery that mutations portions a P. gene encoding kelch (K13)–propeller domains major determinant has provided opportunities for monitoring such on scale.
The recent emergence of artemisinin-resistant Plasmodium falciparum malaria in western Cambodia could threaten prospects for elimination. Identification the genetic basis resistance would provide tools molecular surveillance, aiding efforts to contain resistance. Clinical trials artesunate efficacy were conducted Bangladesh, northwestern Thailand near Myanmar border, and at two sites Cambodia. Parasites collected from trial participants genotyped 8,079 single nucleotide polymorphisms (SNPs)...
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene play an important role Parkinson's disease (PD) pathogenesis, and downregulation of LRRK2 has become a promising therapy for PD. Here, we developed synthetic biology strategy self-assembly delivery small interfering RNAs (siRNAs) into substantia nigra via extracellular vesicles (sEVs) using genetic circuit (in form naked DNA plasmid) to attenuate PD-like phenotypes mouse model.
Red foxes (Vulpes vulpes) have recently been recognized as potential reservoirs of several vector-borne pathogens and a source infection for domestic dogs humans, mostly due to their close vicinity urban areas frequent exposure different arthropod vectors. The aim this study was investigate the presence distribution Babesia spp., Hepatozoon canis, Anaplasma Bartonella 'Candidatus Neoehrlichia mikurensis', Ehrlichia Rickettsia spp. blood filaroid nematodes in free-ranging red from Bosnia...
Culex pipiens complex taxa differ in behaviour, ecophysiology and epidemiologic importance. Despite their significance, information on genetic diversity, occurrence seasonal spatial distribution patterns of the Cx. is still insufficient. Assessment forms congener torrentium crucial for understanding vector–pathogen dynamics. Female mosquitoes were trapped from April–October 2014 twice a month 24-h time period with BG-sentinel traps at 24 sampling sites eastern Austria, using carbon dioxide...
Austria's mammalian wildlife comprises a large variety of species, acting and interacting in different ways as reservoir intermediate definitive hosts for pathogens that can be transmitted to pets and/or humans. Foxes other wild canids are responsible maintaining zoonotic agents, e.g. Echinococcus multilocularis, well pet-relevant pathogens, Hepatozoon canis. Together with the canids, less commonly felids, rodents play major role paratenic hosts. They carry viruses such tick-borne...
YAP/TEAD signaling is essential for organismal development, cell proliferation, and cancer progression. As a transcriptional coactivator, how YAP activates its downstream target genes incompletely understood. forms biomolecular condensates in response to hyperosmotic stress, concentrating transcription-related factors activate genes. However, whether under other signals, organize function, transcription general are unknown. Here, we report that endogenous sub-micron scale Hippo pathway...
Angiostrongylus chabaudi (arrows) on the endothelium of right ventricle a wildcat in Northern Greece
The WHO has reported that RDT and microscopy-confirmed malaria cases have declined in recent years. However, it is still unclear if this reflects a real decrease incidence Bangladesh, as particularly the hilly forested areas of Chittagong Hill Tract (CHT) Districts report more than 80% all deaths. surveillance epidemiological data on from CHT are limited; existing Plasmodium falciparum vivax dominant species.A cross-sectional survey was conducted District Bandarban, southernmost three Tracts...
The red fox (Vulpes vulpes) is a widespread species, harbouring many pathogens relevant for humans and pets. Indeed, Anaplasma spp., Ehrlichia canis Rickettsia spp. among the bacteria Hepatozoon as well Babesia sp. parasites have been focus of several studies. In cohort 36 foxes shot on one day in north-eastern part Austria, microti-like were found 50%, while H. was detected 58.3% samples. spleen more useful detection canis, whereas B. frequently blood. Bacteria could not be confirmed any...
SUMMARY Red fox ( Vulpes vulpes ) is the most abundant wild canid species in Austria, and it a well-known carrier of many pathogens medical veterinary concern. The main aim present study was to investigate occurrence diversity protozoan, bacterial filarial parasites transmitted by blood-feeding arthropods red population western Austria. Blood n = 351) spleen 506) samples from foxes were examined PCR sequencing following identified: Babesia canis , cf. microti (syn. Theileria annae ),...
Abstract Background Plasmodium ovale curtisi and wallikeri are perceived as relapsing malarial parasites. Contrary to vivax, direct evidence for this hypothesis is scarce. The aim of prospective study was characterize the reappearance patterns Methods P. spp. infected patients were treated with artemether-lumefantrine followed biweekly up 1 year detection reappearing parasitemia. Molecular analysis isolates performed identify homologous by genotyping define cases relapse following predefined...
Hippoboscid flies (Diptera: Hippoboscidae), also known as louse or keds, are obligate blood-sucking ectoparasites of animals, and accidentally humans. The potential role hippoboscids vectors human veterinary pathogens is being increasingly investigated, but the presence distribution infectious agents in still unknown parts Europe. Here, we report use molecular genetics to detect characterize vector-borne hippoboscid infesting domestic wild animals Austria.Louse were collected from naturally...
In the River Traun in Austria, diseased European chub Squalius cephalus were observed for several years. 2019, an investigation of condition revealed presence myxozoan species different tissues, without evidence other pathogens. The most prevalent and abundant parasite organs was Myxobolus ellipsoides ex S. cephalus, a formerly only reported to infect fin chub. To further investigate tissue tropism molecular data this parasite, samples from 11 13 collected 1 yr later examined with various...