A5014071855- Parasitic Diseases Research and Treatment
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Helminth infection and control
- Mosquito-borne diseases and control
- Coccidia and coccidiosis research
- Vector-borne infectious diseases
- Insect symbiosis and bacterial influences
- Viral Infections and Vectors
- Parasitic Infections and Diagnostics
- Parasitic infections in humans and animals
- Vector-Borne Animal Diseases
- Studies on Chitinases and Chitosanases
- Zoonotic diseases and public health
- Cardiovascular Conditions and Treatments
- Allergic Rhinitis and Sensitization
- Mollusks and Parasites Studies
- Leptospirosis research and findings
- Nematode management and characterization studies
- Bat Biology and Ecology Studies
- Peptidase Inhibition and Analysis
- Climate Change and Health Impacts
- Protease and Inhibitor Mechanisms
- Veterinary medicine and infectious diseases
- Congenital Anomalies and Fetal Surgery
Instituto de Recursos Naturales y Agrobiología de Salamanca
2017-2025
Czech Academy of Sciences
2023
Ollscoil na Gaillimhe – University of Galway
2022
Sechenov University
2019-2020
Instituto de Investigación Biomédica de Salamanca
2012-2017
Universidad de Salamanca
2009-2017
REVIEW article Front. Physiol., 12 June 2012Sec. Systems Biology Archive Volume 3 - 2012 | https://doi.org/10.3389/fphys.2012.00196
Angiostrongylus chabaudi (arrows) on the endothelium of right ventricle a wildcat in Northern Greece
Abstract Human fascioliasis is a worldwide, pathogenic food-borne trematodiasis. Impressive clinical pictures comprising puzzling polymorphisms, manifestation multifocality, disease evolution changes, sequelae and mortality, have been reported in patients presenting with neurological, meningeal, neuropsychic ocular disorders caused at distance by flukes infecting the liver. Proteomic mass spectrometry analyses of Fasciola hepatica excretome/secretome identified numerous, several new,...
Plasmin, the final product of fibrinolysis, is a broad-spectrum serine protease that degrades extracellular matrix (ECM) components, function exploited by multiple pathogens for dissemination purposes. The trematode Fasciola hepatica leading cause fasciolosis, major disease livestock and an emerging zoonosis in humans. Infection success depends on ability F. newly excysted juveniles (FhNEJ) to penetrate host intestinal wall, process remains incompletely understood. We have previously shown...
We analyze through a climatic model the influence of regional warming on geographical spreading and potential risk infection human dirofilariosis in Russia, Ukraine, other post-Soviet states from 1981 to 2011 estimate situation by 2030. The correctly predicts spatiotemporal location 97.10% 2154 clinical cases reported area during studied period, identified retrospective review literature. There exists also significant correlation between annual predicted Dirofilaria generations calculated...
Background The trematode Fasciola hepatica is the most widespread causative agent of fasciolosis, a parasitic disease that mainly affects humans and ruminants worldwide. During F . infection, newly excysted juveniles (FhNEJ) emerge in duodenum mammalian host migrate towards their definitive location, intra-hepatic biliary ducts. Understanding how traverses intestinal wall migrates liver pivotal for development more successful strategies against fasciolosis. central enzyme fibrinolytic system...
Dirofilaria immitis is the causal agent of canine and feline cardiopulmonary dirofilariasis. Moreover, existence dirofilariasis implies a risk for human populations living in an endemic area which, parasite can cause pulmonary The Spanish epidemiological situation not well understood, lacking data from many central Northern provinces. In our study, on La Rioja (Northern Spain) have been obtained first time. overall prevalence D. dogs was 12% (9% patent 3% occult infections), being 11.6%...
Heartworm infection (Dirofilaria immitis) can cause kidney damage due to the presence of circulating microfilariae (mf) that contribute production and deposit immune complexes. It has been shown mf are a major source Wolbachia antigen during active infection. Here authors compared urine samples from 19 naturally infected dogs with (mf+) 12 without (mf−) for proteinuria anti-Wolbachia Surface Protein (-WSP) IgG in ELISA. Kidneys 6 mf+ 3 mf− were also examined by anti-WSP...
Proliferative endarteritis is one of the key pathological mechanisms cardiopulmonary dirofilariosis, a cosmopolitan parasitosis caused by Dirofilaria immitis affecting dogs and cats around world. It has been shown that excretory/secretory antigens from D. adult worms (DiES) bind plasminogen (PLG) activate fibrinolysis, which can lead to survival mechanism for parasite in its intravascular environment. However, overproduction plasmin (final product route) related processes similar those...