A5018821026- Viral Infections and Vectors
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- Insect and Pesticide Research
- Malaria Research and Control
- Insect symbiosis and bacterial influences
- Bartonella species infections research
- Insect Pest Control Strategies
- Plant Virus Research Studies
- Dengue and Mosquito Control Research
- Bird parasitology and diseases
- Animal Disease Management and Epidemiology
- Zoonotic diseases and public health
- Rabies epidemiology and control
- Dermatological diseases and infestations
- Viral Infections and Outbreaks Research
- Yersinia bacterium, plague, ectoparasites research
- Biosensors and Analytical Detection
- Toxoplasma gondii Research Studies
- Toxin Mechanisms and Immunotoxins
- Plant Parasitism and Resistance
- Plant and Fungal Interactions Research
- COVID-19 epidemiological studies
- Herpesvirus Infections and Treatments
Bipar
2016-2025
École Nationale Vétérinaire d'Alfort
2016-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2013-2024
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2014-2024
Département Santé Animale
2013-2024
Institut Pasteur
2007-2022
Centre National de la Recherche Scientifique
2022
Université Paris Cité
2022
Orano (United States)
2021
BackgroundA Chikungunya (CHIK) outbreak hit La Réunion Island in 2005–2006. The implicated vector was Aedes albopictus. Here, we present the first study on susceptibility of Ae. albopictus populations to sympatric CHIKV isolates from and compare it other virus/vector combinations.Methodology FindingsWe orally infected 8 collections 3 Mayotte collected March 2006 with two virus (CHIKV) Réunion: (i) strain 05.115 June 2005 an Alanine at position 226 glycoprotein E1 (ii) 06.21 November a...
Background Aedes aegypti and albopictus are potential vectors of chikungunya virus (CHIKV). The recent CHIKV outbreaks were caused by a new variant characterized mutation in the E1 glycoprotein gene (E1-226V) which has favored better transmissibility Ae. albopictus. As tends to replace many regions, one question remained: is as efficient transmit E1-226V CHIKV? Methodology Findings We infected orally both species with estimated infection, viral dissemination, transmission rate real time...
Due to increased travel, climatic, and environmental changes, the incidence of tick-borne disease in both humans animals is increasing throughout Europe. Therefore, extended surveillance tools are desirable. To accurately screen pathogens, a large scale epidemiological study was conducted on 7050 Ixodes ricinus nymphs collected from France, Denmark, Netherlands using powerful new high-throughput approach. This advanced methodology permitted simultaneous detection 25 bacterial, 12 parasitic...
Introduction Ticks are the most common arthropod vectors of both human and animal diseases in Europe, Ixodes ricinus tick species is able to transmit a large number bacteria, viruses parasites. may also be co-infected with several pathogens, subsequent high likelihood co-transmission humans or animals. However few data exist regarding co-infection prevalences, these studies only focus on certain well-known pathogens. In addition ticks carry symbionts that play important roles biology, could...
The yellow fever virus (YFV) caused a severe outbreak in Brazil 2016-2018 that rapidly spread across the Atlantic Forest its most populated region without viral circulation for almost 80 years. A comprehensive entomological survey combining analysis of distribution, abundance and YFV natural infection mosquitoes captured before during was conducted 44 municipalities five Brazilian states. In total, 17,662 89 species were collected. Before evidence circulation, tested negative but traditional...
Since its discovery in Nigeria 1991, Aedes albopictus has invaded much of Central Africa, a region where Ae. aegypti also occurs. To assess the relationship between invasion by and recent emergence dengue virus (DENV) chikungunya (CHIKV), we undertook vector competence experiments on populations collected from Cameroon conducted field investigations during concurrent epidemics DENV CHIKV Gabon. Overall, infection dissemination rates were not significantly different when exposed to titers...
We evaluated the ability of three mosquito species (Aedes caspius, Aedes detritus, Culex pipiens), collected in southern France and Tunisia, different laboratory-established colonies aegypti, albopictus, vexans, Anopheles gambiae, pipiens, quinquefasciatus) to disseminate two strains Rift Valley fever virus (RVFV), virulent ZH548 avirulent Clone 13. After feeding on an infectious blood meal at 10(8.5) plaque-forming units/mL, females were maintained 30 degrees C for 14 days. Surviving tested...
Ticks are highly susceptible to global environmental and socio-economical changes. Several tick-borne pathogens have been reported in new geographical regions while species, strains or genetic variants of microorganisms continually being detected. However, still poorly understood, it is estimated that half all human disease has an unknown origin. Therefore order prevent these diseases, more effort required identify unexpected pathogens. Ixodes ricinus the vector for a broad range bacterial...
Abstract Background Ticks and tick-borne pathogens (TTBP) are a major constraint to livestock production in Pakistan; despite high prevalence of TTBPs, knowledge on the capacity Pakistani ticks carry endosymbionts is limited. Furthermore, mixed infections with multiple microorganisms further complicate limit detection potential traditional diagnostic methods. The present study investigated bovine Pakistan, employing high-throughput microfluidic real-time PCR based technique. Methods were...
Abstract Certain Bartonella species are known to cause afebrile bacteremia in humans and other mammals, including B. quintana, the agent of trench fever, henselae, cat scratch disease. Reports have indicated that animal-associated may paucisymptomatic endocarditis humans. We identified potentially zoonotic strains from 6 samples patients who had chronic, subjective symptoms reported tick bites. Three were henselae 3 spp. (B. doshiae, schoenbuchensis, tribocorum). Genomic analysis isolated...
Identifying Borrelia burgdorferi as the causative agent of Lyme disease in 1981 was a watershed moment understanding major impact that tick-borne zoonoses can have on public health worldwide, particularly Europe and USA. The medical importance diseases has long since been acknowledged, yet little is known regarding occurrence emerging pathogens such spp., Anaplasma phagocytophilum, Rickettsia Bartonella "Candidatus Neoehrlichia mikurensis", encephalitis virus questing ticks Romania, gateway...
In France as elsewhere in Europe the most prevalent TBD humans is Lyme borreliosis, caused by different bacterial species belonging to Borrelia burgdorferi sensu lato complex and transmitted important tick France, Ixodes ricinus. However, diagnosis of disease not always confirmed unexplained syndromes occurring after bites have become an issue. Recently, B. miyamotoi relapsing fever group same has been involved human Russia, USA Netherlands. present study, we investigate presence along with...
Jingmenvirus is a recently identified group of segmented RNA viruses phylogenetically linked with unsegmented Flaviviridae viruses. Primarily in various tick genera originating China, geographical distribution has rapidly expanded to cover Africa, South America, Caribbean, and Europe. The identification Jingmen-related mammals, including febrile humans, opens the possibility that Jingmenviruses may be novel tick-borne arboviruses. In this study, we aimed at increasing knowledge host range,...
The tick midgut and salivary glands represent the primary organs for pathogen acquisition transmission, respectively. Specifically, is first organ to have contact with pathogens during blood meal uptake, while along their secretions play a crucial role in transmission host. Currently there little data about composition prevalence Ixodes ricinus glands. present study investigated presence of 32 species unfed I. males females using high-throughput microfluidic real-time PCR. Such an approach...
Anaplasma ovis is a major cause of small ruminant anaplasmosis, tick-borne disease mainly affecting ruminants in tropical and subtropical regions the world. Due to health production problems dairy goat flocks Corsica, France, demonstration A. infection some animals, an extensive survey was conducted island spring 2016. The aim determine prevalence geographical distribution infections goats ticks as well possible relationships with anaemia other indicators. In addition, genetic diversity...
Corsica is a mountainous French island in the north-west of Mediterranean Sea presenting large diversity natural environments where many interactions between humans, domestic animals and wild fauna occur. Despite this favourable context, tick-borne pathogens (TBPs) have not systematically been investigated. In study, number TBPs were screened ticks collected over period one year from hosts Corsica. More than 1,500 belonging to nine species five genera (Rhipicephalus, Hyalomma, Dermacentor,...
Emerging zoonoses caused by previously unknown agents are one of the most important challenges for human health because their inherent inability to be predictable, conversely emergences known that could targeted routine surveillance programs. zoonotic infections either originate from increasing contacts between wildlife and populations, or geographical expansion hematophagous arthropods act as vectors, this latter being more capable impact large-scale populations. While characterizing viral...
Tick-borne encephalitis virus' (TBEV) geographic range and the human incidence are increasing throughout Europe, putting a number of non-endemic regions countries at risk outbreaks. In spring 2020, there was an outbreak tick-born (TBE) in Ain, Eastern France, where virus had never been detected before. All patients but one consumed traditional unpasteurised raw goat cheese from local producer. We conducted investigation suspected farm using integrative One Health approach. Our methodology...
Ixodes ricinus ticks (Acari: Ixodidae) are the most important vector for Lyme borreliosis in Europe. As climate change might affect their distributions and activities, this study aimed to determine effects of environmental factors, i.e., meteorological, bioclimatic, habitat characteristics on host-seeking (questing) activity I. nymphs, an stage disease transmissions, across diverse climatic types France over 8 years. Questing was observed using a repeated removal sampling with cloth-dragging...
Tick-borne encephalitis (TBE) is a viral disease endemic in Eurasia. The virus mainly transmitted to humans via ticks and occasionally the consumption of unpasteurized milk products. European Centre for Disease Prevention Control reported an increase TBE incidence over past years Europe as well emergence new areas. To better understand this phenomenon, we investigated drivers through expert knowledge elicitation. We listed 59 possible grouped eight domains elicited forty experts to: (i)...
Abstract Background Ticks can transmit a broad variety of pathogens medical importance, including Borrelia afzelii , the causative agent Lyme borreliosis in Europe. Tick microbiota is an important factor modulating, not only vector physiology, but also competence. Anti-microbiota vaccines targeting keystone taxa tick alter feeding and modulate taxonomic functional profiles bacterial communities vector. However, impact anti-microbiota vaccine on tick-borne pathogen development within has been...