Rodrigo Fabiano do Carmo Said
A5002038310- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Malaria Research and Control
- Vector-borne infectious diseases
- Insect Pest Control Strategies
- Fish biology, ecology, and behavior
- COVID-19 epidemiological studies
- Virology and Viral Diseases
- Insect symbiosis and bacterial influences
- interferon and immune responses
- COVID-19 and Mental Health
- Vibrio bacteria research studies
- Phytoplasmas and Hemiptera pathogens
- Public Health and Social Inequalities
- Primate Behavior and Ecology
- Immune Cell Function and Interaction
- COVID-19 Clinical Research Studies
- Aquaculture disease management and microbiota
- HIV/AIDS oral health manifestations
- Health, Nursing, Elderly Care
- Herpesvirus Infections and Treatments
- Syphilis Diagnosis and Treatment
Pan American Health Organization (Brasil)
2020-2025
Ministério da Saúde
2019-2020
Secretaria da Saúde
2020
Ministério da Saúde
2020
The yellow fever virus (YFV) caused a severe outbreak in Brazil 2016-2018 that rapidly spread across the Atlantic Forest its most populated region without viral circulation for almost 80 years. A comprehensive entomological survey combining analysis of distribution, abundance and YFV natural infection mosquitoes captured before during was conducted 44 municipalities five Brazilian states. In total, 17,662 89 species were collected. Before evidence circulation, tested negative but traditional...
Arbovirus infections in Brazil, including yellow fever, dengue, zika, and chikungunya, result considerable morbidity mortality are pressing public health concerns. However, our understanding of these outbreaks is hampered by the limited availability genomic data. In this study, we investigated genetic diversity spatial distribution YFV during current outbreak analyzing data from areas southeastern Brazil not covered other previous studies. To gain insights into routes introduction...
Brazil experienced a large dengue virus (DENV) epidemic in 2019, highlighting continuous struggle with effective control and public health preparedness. Using Oxford Nanopore sequencing, we led field classroom initiatives for the monitoring of DENV Brazil, generating 227 novel genome sequences DENV1-2 from 85 municipalities (2015-2019). This equated to an over 50% increase number genomes available databases. both phylogenetic epidemiological models retrospectively reconstructed recent...
Abstract The emergence and reemergence of mosquito-borne diseases in Brazil such as yellow fever, zika, chikungunya, dengue have had serious impacts on public health. Concerns been raised due to the rapid dissemination chikungunya virus across country since its first detection 2014 Northeast Brazil. In this work, we carried out on-site training activities genomic surveillance partnership with National Network Public Health Laboratories that led generation 422 genomes from 12 Brazilian states...
Objective To characterize the clinical manifestations of yellow fever disease and identify risk factors for mortality. Methods A retrospective study was conducted in referral center infectious diseases (Hospital Eduardo de Menezes-HEM) Belo Horizonte, Minas Gerais, Brazil. Analysis included data from 283 patients with confirmed YF infection older than 13 years old who presented to HEM between January 2017 June 2018. In-hospital mortality (hypothesis formulated after collection), demographic...
The Northeast region of Brazil registered the second-highest incidence proportion Chikungunya fever in 2019. In that year, an outbreak consisting patients presenting with febrile disease associated joint pain was reported by public primary health care service city Natal, state Rio Grande do Norte, March At first, aetiological agent undetermined. Since much is still unknown about chikungunya virus' (CHIKV) genomic diversity and evolutionary history this northeasternmost state, we used a...
Yellow fever virus (YFV) causes a clinical syndrome of acute hemorrhagic hepatitis. YFV transmission involves non-human primates (NHP), mosquitoes and humans. By late 2016, Brazil experienced the largest outbreak last 100 years, with 2050 human confirmed cases, 681 cases ending in death 764 epizootic NHP. Among affected areas, Bahia state Northeastern was only region no autochthonous cases. using next generation sequence approach, we investigated molecular epidemiology NHP discuss what...
The yellow fever (YF) vaccine consists of an attenuated virus, and despite its relative safety, some adverse events following YF vaccination have been described. At the end 2016, Brazil experienced most massive sylvatic outbreak over last 70 years intense campaign occurred in Minas Gerais state Southeast from 2016 to 2018. present study aimed develop a genotyping tool investigate 21 cases suspected vaccination. Initial silico analyses were performed using partial NS5 nucleotide sequences...
Since 2005, chikungunya virus (CHIKV) has caused large outbreaks, with reports of more than 10 million cases worldwide over the course a decade.Since 2013, almost three have been reported in Americas.Although musculoskeletal involvement is most prevalent symptom disease spectrum, systemic manifestations important organs also described.Currently, case classifications based on intensity and duration articular symptoms used to guide clinical management joint manifestations, little or no...
Since its discovery in early 1916, dengue fever, a common vector-borne illness Brazil, has resulted extensive urban outbreaks and poses serious threat to the public’s health. Understanding dynamics of Dengue Virus (DENV) serotypes circulating different regions Brazil is essential for implementing effective disease control prevention measures. In response this urgent need, we conducted an on-site training program genomic surveillance collaboration with Central Laboratory Health Secretary Mato...
During these past years, several studies have provided serological evidence regarding the circulation of West Nile virus (WNV) in Brazil. Despite some reports, much is still unknown genomic diversity and transmission dynamics this country. Recently, monitoring activities horses revealed WNV Brazilian regions. These findings on paucity data reinforce need for prompt investigation infection horses, which may precede human cases encephalitis Thus, study, we retrospectively screened 54...
Objetivo: investigar os casos de febre maculosa, verificar aspectos relacionados à assistência saúde e caracterizar o perfil epidemiológico desses do ambiente infecção. Métodos: estudo descritivo dos confirmados FM entre janeiro novembro 2017. Foi elaborado um formulário semiestruturado para coleta dados. Para as análises epidemiológicas, foram utilizados programas EpiInfoTM 7 Qgis® 2.18.1. Foram calculadas frequências, medidas tendência central, dispersão indicadores oportunidade...
The emergence and continued geographic expansion of arboviruses the growing number infected people have highlighted need to develop improve multiplex methods for rapid specific detection pathogens. Sequencing technologies are promising tools that can help in laboratory diagnosis conditions share common symptoms, such as pathologies caused by emerging arboviruses. In this study, we integrated nanopore sequencing advantages reverse transcription polymerase chain reaction (RT-PCR) a RT-PCR...
This study examines the epidemiological and genomic characteristics, along with transmission dynamics, of SARS-CoV-2 within prison units I II in Campo Grande, Mato Grosso do Sul, Brazil. Conducted between May October 2022, it reveals how virus spreads confined settings prisons, emphasizing roles overcrowded cells, frequent transfers, limited healthcare access. The research involved 1927 participants (83.93% total population) utilized nasopharyngeal swabs RT-qPCR testing for detection....
Objetivo: Apresentar a varredura espacial como instrumento para identificar clusters de dengue e fatores associados à epidemias em Belo Horizonte/MG. Métodos: Estudo ecológico, com casos notificados entre 2007 2010. Para identificação utilizou-se estatística Scan. A regressão logística investigou associação o índice infestação predial (IIP), proporção imóveis verticalizados (PIV), densidade ovos Ae. aegypti (DO), cobertura visitas agentes endemia populacional. Resultados: Ocorreram 76.592...
ABSTRACT The recent re-emergence of yellow fever virus (YFV) in Brazil has raised serious concerns due to the virus’ rapid dissemination southeastern region. To better understand YFV genetic diversity and dynamics during outbreak we generated 18 complete near-complete genomes from peak epidemic curve non-human primates (NHPs) human infected cases across Espírito Santo Rio de Janeiro states. Genomic sequencing revealed timing, source likely routes transmission dispersion one largest outbreaks...
ABSTRACT Background Brazil has experienced a large dengue virus (DENV) epidemic in 2019, highlighting continual struggle with effective control and public health preparedness. is world leader real-time genomic surveillance of arboviruses, although such technology expertise remains inaccessible for the vast majority local researchers workers. In we led field classroom initiatives DENV Brazil. Methods Oxford Nanopore MinION was used sequencing, focusing on generating DENV1 DENV2 complete...
ABSTRACT The Northeast region of Brazil registered the second highest incidence proportion chikungunya fever in 2019. In that year an outbreak consisting patients presented with febrile disease associated joint pain were reported by public primary health care service city Natal, Rio Grande do Norte state, March At first, aetiological agent was undetermined. Since much is still unknown about virus (CHIKV) genomic diversity and evolutionary history this northeasternmost we used a combination...
The emergence and reemergence of mosquito-borne diseases in Brazil such as Yellow Fever, Zika, Chikungunya, Dengue have had serious impacts on public health. Concerns been raised due to the rapid dissemination chikungunya virus (CHIKV) across country since its first detection 2014 Northeast Brazil. Faced with this scenario, on-site training activities genomic surveillance carried out partnership National Network Public Health Laboratories led generation 422 CHIKV genomes from 12 Brazilian...