- Fungal Infections and Studies
- Research on Leishmaniasis Studies
- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Plant Pathogens and Fungal Diseases
- Tuberculosis Research and Epidemiology
- Trypanosoma species research and implications
- Reproductive tract infections research
- COVID-19 Impact on Reproduction
- interferon and immune responses
- Mycobacterium research and diagnosis
- Chronic Lymphocytic Leukemia Research
- Viral Infections and Outbreaks Research
- Adolescent Sexual and Reproductive Health
- Infectious Disease Case Reports and Treatments
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Muscle and Compartmental Disorders
- Dermatological and COVID-19 studies
- Autoimmune Neurological Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Healthcare Regulation
- Peripheral Neuropathies and Disorders
Universidade Federal do Rio Grande do Norte
2018-2025
Instituto de Medicina Tropical
2020-2021
Universidade de São Paulo
2010
Sporotrichosis is a worldwide subcutaneous mycosis caused by Sporothrix spp. In the past, this infection was associated with armadillo hunting, horticulturists, miners, and gardeners, being considered an implantation acquired plant debris injury. Nevertheless, since late nineties, it has been zoonotic disease in Brazil. Here we report case series of 121 patients cat-transmitted sporotrichosis seen Northeast Brazil.Patient's demographic, clinical data, length treatment were recorded....
In late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as cause of a cluster pneumonia cases in China, and corresponding disease was designated Coronavirus Disease 2019 (COVID-19), spreading quickly around world resulting pandemic. COVID-19 is associated with set coagulation abnormalities that increase risk thromboembolic events, especially patients severe/critical disease. We describe series five mild COVID-19, treated an outpatient clinic, which, after...
Background A relevant case of pulmonary sporotrichosis due to Sporothrix brasiliensis is reported in a 50-year-old immunocompetent woman who had no history skin trauma, but was close contact with several stray cats at her nap time. The patient hospitalized after 7 months illness. survey conducted for tuberculosis, an endemic disease Brazil. She presented multiple central nodules images, cavitation. Methodology/Principal findings bronchoalveolar lavage cultured and sp. growth obtained. Then,...
The Northeast region of Brazil registered the second-highest incidence proportion Chikungunya fever in 2019. In that year, an outbreak consisting patients presenting with febrile disease associated joint pain was reported by public primary health care service city Natal, state Rio Grande do Norte, March At first, aetiological agent undetermined. Since much is still unknown about chikungunya virus' (CHIKV) genomic diversity and evolutionary history this northeasternmost state, we used a...
Kodamaea ohmeri is an emerging and opportunistic yeast associated with a high mortality rate in humans. As it commonly found the environment, possible that environmental conditions agricultural practices contribute to adaptation of this selection antifungal resistance. During multicentric study Brazil, conducted under One Health perspective, 14 isolates K. were identified from different sources: three blood cultures, animals (swine poultry), eight animal environments poultry). Yeasts...
Background Leishmania infantum can be an opportunistic pathogen, with immunocompromised status increasing the risk of converting asymptomatic infection to symptomatic visceral leishmaniasis (VL). VL has approximately 5% fatality rate; and HIV coinfection (AIDS/VL) increases this risk. We hypothesized that, relative those alone, people co-infection would have altered T cell activation which could impact on VL. Methods A cross-sectional study was performed between 2014 2016 determine...
To (i) describe the nationwide antimicrobial susceptibility of Neisseria gonorrhoeae (NG) isolates cultured across Brazil in 2018-20 and compare it with NG resistance data from 2015-16, (ii) present epidemiological corresponding gonorrhoea patients 2018-20.Twelve representative sentinel sites men urethral discharge. Susceptibility to eight antimicrobials was examined using agar dilution method, according WHO standards. The consenting participants were invited provide data.In total, 633 (one...
ObjectivesTo determine the effects of in-utero exposure to maternal SARS-CoV-2 infection on offspring's neurodevelopment during first year life.MethodsWe performed a prospective cohort babies exposed pregnancy, and control group (CG) unexposed in low-income area Brazil. Children's was assessed using guide for Monitoring Child Development Integrated Management Childhood Illness context both groups (at 1,2,3,4,5,6, 9, 12 months), Ages & Stages Questionnaire (ASQ-3) (EG) 4, 6 months).ResultsWe...
Abstract Objectives Regular quality-assured WGS with antimicrobial resistance (AMR) and epidemiological data of patients is imperative to elucidate the shifting gonorrhoea epidemiology, nationally internationally. We describe dynamics gonococcal population in 11 cities Brazil between 2017 2020 emerging disappearing lineages associated AMR, compare Brazilian AMR from 2015 2016, explain recent changes epidemiology. Methods was performed using Illumina NextSeq 550 genomes 623 isolates were used...
COVID-19 is a viral disease caused by SARS-CoV-2 that compromises the host immune response in severe cases, promoting hyperinflammation results acute lung injury and multiple organs failure. In this context, patients presenting with immune-related diseases, such as Crohn's disease, affected COVID-19, may have an uncertain prognosis. We report on case of young female patient presented pneumonia favorable outcome even maintaining use adalimumab, TNF - alpha inhibitor prednisone. This raises...
Leishmania infantum is an opportunistic parasitic infection. An immunocompromised state increases the risk of converting asymptomatic infection to symptomatic visceral leishmaniasis (VL), which has a ~5% fatality rate even with treatment. HIV coinfection death from VL.A cross-sectional study was performed between 2014 and 2016 determine prevalence L. in positive subjects residing Rio Grande do Norte, Brazil (n=1,372) these subgroup were followed longitudinally. Subsequent incident cases VL...
Rhodococcus equi is a facultative aerobic, intracellular, non-motile, non-spore-forming, Gram-positive, weakly acid-fast coccobacillus belonging to the group of nocardioform actinomycetes. R. infections are rare opportunistic illnesses in patients with Acquired Immunodeficiency Syndrome (AIDS), associated high mortality rate. The most common clinical presentation chronic cavitary pneumonia. Due its acid-fastness, can be mistaken for others organisms, as Mycobacterium tuberculosis. In turn,...
ABSTRACT The Northeast region of Brazil registered the second highest incidence proportion chikungunya fever in 2019. In that year an outbreak consisting patients presented with febrile disease associated joint pain were reported by public primary health care service city Natal, Rio Grande do Norte state, March At first, aetiological agent was undetermined. Since much is still unknown about virus (CHIKV) genomic diversity and evolutionary history this northeasternmost we used a combination...
Objetivo: identificar as variáveis importantes para compor uma avaliação interdisciplinar da pessoa com COVID-19 grave e assim elaborar um bundle. Metodologia: Este é estudo qualitativo do tipo revisão integrativa. Realizou-se buscas nas seguintes bases de dados: Science Direct, Scientific Electronic Library Online, Literatura Latino Americana Caribe em Ciências Saúde, Scopus Web of Science. Como critérios inclusão, foram selecionados estudos que abordassem o tema estivessem disponíveis...
A hepatite é uma doença infectocontagiosa causada pelo vírus da (HAV), que transmitido mormente via fecal-oral, incluindo sexo oral-anal. Entre usuários de profilaxia pré-exposição ao HIV (PrEP HIV) no Brasil, dos quais 83% são gays e HSH, recomenda-se avaliar a susceptibilidade HAV por sorologia para fins prevenção. Este estudo teve objetivo prevalência anticorpos Anti-HAV IgG/total entre HSH em uso PrEP caracterizar suas práticas sexuais. Estudo transversal, realizado agosto/2021...
Entre pessoas que vivem com HIV/Aids (PVHA), a realização anual de teste tuberculínico cutâneo (PPD) ou interferon-γ release assay (IGRA) é recomendada pelo Ministério da Saúde do Brasil para investigação tuberculose (TB) latente pacientes contagem linfócitos T CD4+ >350 cel/mm3 não tenham tratamento prévio, indicação atual TB latente. Ainda há incertezas sobre eficácia e concordância dos dois testes no diagnóstico em PVHA cenário epidemiológico brasileiro. A entre os pode variar acordo...
Infecções do sistema nervoso central por Mycobacterium tuberculosis podem se apresentar como comprometimento meníngeo, aracnoidite espinhal ou formação de tuberculomas, geralmente localizados nos hemisférios cerebrais cerebelares. Apresentamos o caso mulher 49 anos, previamente hígida, com queixa cefaleia hemicraniana irradiação periorbital e diplopia há 01 mês, sem dor ocular, hiperemia lacrimejamento. Ao exame oftalmológico, apresentava pupilas isocóricas fotorreagentes, estrabismo...