A5036186021- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Malaria Research and Control
- COVID-19 epidemiological studies
- Respiratory viral infections research
- Global Maternal and Child Health
- COVID-19 Clinical Research Studies
- Influenza Virus Research Studies
- Zoonotic diseases and public health
- Virology and Viral Diseases
- Education during COVID-19 pandemic
- Global Health and Epidemiology
- Maternal and Neonatal Healthcare
- Healthcare Regulation
- Vector-Borne Animal Diseases
- SARS-CoV-2 and COVID-19 Research
- Indigenous Health and Education
- Healthcare during COVID-19 Pandemic
- Vector-borne infectious diseases
- Dental Research and COVID-19
- Health, Nursing, Elderly Care
- Travel-related health issues
- Parasite Biology and Host Interactions
- Parasites and Host Interactions
Faculdade São Leopoldo Mandic
2016-2025
University of Manchester
2021
Secretaria Municipal de Saúde
2017-2020
Universidade Estadual de Campinas (UNICAMP)
2007-2019
Fundação Oswaldo Cruz
2019
Instituto de Saúde
2019
Universidade Federal da Bahia
2019
Secretaria da Saúde
2017-2018
Processus Infectieux en Milieu Insulaire Tropical
2018
Universidad Iberoamericana
2018
ABSTRACT Arboviruses have been emerging in different parts of the world due to genetic changes virus, alteration host and vector population dynamics, or because anthropogenic environmental factors. These viruses’ capacity for adaptation is notable, as well likelihood their emergence establishment new geographic areas. In Brazilian epidemiologic scenario, most common arboviruses are DENV, CHIKV, ZIKV, although others may spread country. Little yet known impact viral co-circulation, which...
For the first time in history it was documented an indigenous transmission of Chikungunya fever Americas Caribbean 2013.Then has been confirmed Oiapoque occurrence Brazil.By October 2014, there were 828 cases country, only 39 pointed as coming from abroad.Interestingly, seems to be two different viral introductions Americas, genotype isolated and is not same analyzed Bahia.
Zika virus (ZIKV) infections have been linked to different levels of clinical outcomes, ranging from mild rash and fever severe neurological complications congenital malformations.We investigated the immunological response, focusing on immune mediators profile in 95 acute ZIKV-infected adult patients Campinas, Brazil. These included 6 pregnant women who later delivered during course this study. Clinical observations were recorded hospitalization. Levels 45 quantified using multiplex...
Since the end of 2020, there has been a great deal international concern about variants SARS-COV-2 B.1.1.7, identified in United Kingdom; B.1.351 discovered South Africa and P.1, originating from Brazilian state Amazonas. The three were associated with an increase transmissibility worsening epidemiological situation places where they expanded. lineage B.1.1.7 was case fatality rate Kingdom. There are still no studies on other two variants. aim this study to analyze mortality profile before...
Abstract Background Chikungunya virus (CHIKV) emerged in the Americas 2013 and has caused approximately 2.1 million cases >600 deaths. A retrospective investigation was undertaken to describe clinical, epidemiological, viral genomic features associated with deaths by CHIKV Ceará state, northeast Brazil. Methods Sera, cerebrospinal fluid (CSF), tissue samples from 100 fatal suspected arbovirus infection were tested for CHIKV, dengue (DENV), Zika (ZIKV). Clinical, death reports obtained...
Despite the considerable morbidity and mortality of yellow fever virus (YFV) infections in Brazil, our understanding disease outbreaks is hampered by limited viral genomic data. Here, through a combination phylogenetic epidemiological models, we reconstructed recent transmission history YFV within different epidemic seasons Brazil. A suitability index based on highly domesticated Aedes aegypti was able to capture seasonality reported human infections. Spatial modeling revealed spatial...
Dengue remains a serious public health problem and until 2013, it was the only arbovirus transmitted by urban species of Aedes mosquitoes in Western Hemisphere. Justifying adoption clinical epidemiological criteria for reporting probable dengue cases, to overcome insufficient laboratory capacity increase sensitivity during large epidemic, cases are those reported as suspected dengue, regardless laboratory.1Secretaria de Vigilância em Saúde – Ministério da do BrasilMonitoring arboviruses:...
Background: Since the end of 2020, there has been a great deal international concern about variants SARS-COV-2 B.1.1.7, identified in United Kingdom; B.1.351 discovered South Africa and P.1, originating from Brazilian state Amazonas. The three were associated with an increase transmissibility worsening epidemiological situation places where they expanded. lineage B.1.1.7 was case fatality rate Kingdom. There are still no studies on other two variants. aim this study to analyze mortality...
Four time-dependent dengue transmission models are considered in order to fit the incidence data from City of Campinas, Brazil, recorded October 1st 1995 September 30th 2012. The entomological parameters allowed depend on temperature and precipitation, while carrying capacity hatching eggs only precipitation. whole period is split into four periods, due fact that model formulated considering circulation one serotype. Dengue human mosquito fitted for each periods. time varying partial overall...
Respiratory syncytial virus (RSV) infection is the leading cause of hospitalisation for respiratory diseases among children under 5 years old. The aim this study was to analyse RSV seasonality in five distinct regions Brazil using time series analysis (wavelet and Fourier series) following indicators: monthly positivity immunofluorescence reaction identified by virologic surveillance system, rate hospitalisations per bronchiolitis pneumonia due old (codes CID-10 J12.1, J20.5, J21.0 J21.9). A...
During 2014-2015, a total of 31 deaths were associated with the first chikungunya epidemic in Puerto Rico. We analyzed excess mortality from various causes for same months during previous 4 years and detected 1,310 possibly attributable to chikungunya. Our findings raise important questions about increased rates
In 2010, introduction of the meningococcal C conjugate vaccine in Brazil for children <2 years provided an immediate reduction incidence rates disease among age groups targeted vaccine, but no early impact was observed unvaccinated groups. Knowledge about carriage is crucial improving our understanding epidemiology and designing effective vaccination programs. Taking account very limited published data currently available describing Brazil, we performed a study to evaluate prevalence...
Chikungunya is an emerging arbovirus that reached the Western Hemisphere at end of 2013. Studies in Indian Ocean and India suggest passive surveillance systems cannot recognize many deaths associated with chikungunya, which can be inferred by increase overall mortality observed during chikungunya epidemics.We assess epidemics most affected states Brazil, from 2015 2016.We studied monthly age group, comparing a period without to epidemic period, we defined arbitrarily as consecutive months...
Since the beginning of SARS-CoV-2 pandemic, numerous restrictive measures have been taken by governments different countries. Recently, due to high possibility transmission in dental offices, there was a recommendation American, European and Brazilian request closing offices. In this commentary, we will give an overview reasons perspectives scenario.
Recent Zika outbreaks in South America, accompanied by unexpectedly severe clinical complications have brought much interest fast and reliable screening methods for ZIKV (Zika virus) identification. Reverse-transcriptase polymerase chain reaction (RT-PCR) is currently the method of choice to detect biological samples. This approach, nonetheless, demands a considerable amount time resources such as kits reagents that, endemic areas, may result substantial financial burden over affected...
In 2014 there was a large chikungunya epidemic in the Dominican Republic, with 539 099 reported cases and 6 deaths. Although is considered low-mortality disease, studies have suggested this an underestimation. This study assessed deaths associated epidemic.Mortality data were obtained from National Statistics Office, surveillance system for acute febrile illnesses, Epidemiological Surveillance System. Expected all-cause mortality by age group estimated using years 2010-2012 as baseline. The...
INTRODUCTION: In March 2020, the World Health Organization declared coronavirus disease (COVID-19) outbreak a pandemic. Brazil, 110 thousand cases and 5,901 deaths were confirmed by end of April 2020. The scarcity laboratory resources, overload on service network, broad clinical spectrum make it difficult to document all due COVID-19. aim this study was assess mortality rate in Brazilian capitals with high incidence METHODS: We assessed weekly between epidemiological week 1 16 2020...
Some patients with dengue fever tend to develop thrombocytopenia during the course of infection and are thus vulnerable haemorrhagic manifestations other complications. However, factors associated development unknown. We aimed identify an increased risk haematological changes in confirmed fever. Retrospective cohort study. Brazilian multicentre primary care databases. 387 had positive laboratory serological confirmation 2014. The data were identified from two databases: Notification Injury...
Abstract Background The State of Ceará, in Northeastern Brazil, suffers from a triple burden arboviruses (dengue, Zika and chikungunya). We measured the seroprevalence chikungunya, dengue its associated factors population Juazeiro do Norte, Southern Ceará State, Brazil. Methods A cross-sectional study analytical spatial analysis was performed to estimate dengue, year 2018. Participants were tested for IgM IgG against these three viruses. Those with and/or positive tests results considered...