A5016825323- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Advanced Chemical Sensor Technologies
- Malaria Research and Control
- Metabolomics and Mass Spectrometry Studies
- Infectious Encephalopathies and Encephalitis
- Mycotoxins in Agriculture and Food
- Parasites and Host Interactions
- Identification and Quantification in Food
- Parasite Biology and Host Interactions
- Biosensors and Analytical Detection
- Helminth infection and control
- Virology and Viral Diseases
- Cystic Fibrosis Research Advances
- Microplastics and Plastic Pollution
- Hops Chemistry and Applications
- Immune Response and Inflammation
- Nutritional Studies and Diet
- Analytical chemistry methods development
- Endometriosis Research and Treatment
- Vibrio bacteria research studies
- Plant Pathogens and Fungal Diseases
- Food Chemistry and Fat Analysis
- Immunotherapy and Immune Responses
- Reproductive Physiology in Livestock
Universidade Estadual de Campinas (UNICAMP)
2016-2022
Universidade Estadual Paulista (Unesp)
2021
Federal Police of Brazil
2018
Migration is a known phenomenon defined as the partitioning of chemical compounds from packaging into food, and depends on several factors. assays are generally time-consuming require specific conditions in order to investigate behavior different situations. Furthermore, these tests often performed with food simulants, since determination migration under real highly impaired. Several methodologies have been designed carry out this study, but an ideal approach should be capable assessing...
Recent outbreaks of Zika virus in Oceania and Latin America, accompanied by unexpected clinical complications, made this infection a global public health concern. This has tropism to neural tissue, leading microcephaly newborns significant proportion infected mothers. The relevance infection, the difficulty perform accurate diagnosis small amount data literature indicate necessity studies on order characterize new biomarkers establish targets for viral control vertebrates invertebrate...
Zika virus (ZIKV) infection has recently emerged as a major concern worldwide due to its strong association with nervous system malformation (microcephaly) of fetuses in pregnant women infected by the virus. Signs and symptoms ZIKV are often mistaken other common viral infections. Since transmission may occur through biological fluids exchange coitus, addition mosquito bite, this condition is an important infectious disease. Thus, understanding mechanism become research focus, well providing...
Weight gain is a metabolic disorder that often culminates in the development of obesity and other comorbidities such as diabetes. Obesity characterized by chronic, subclinical systemic inflammation, regarded remarkably important factor contributes to comorbidities. Therefore, laboratory methods allow identification subjects at higher risk for severe weight-associated morbidity are utter importance, considering health safety populations. This contribution analyzed plasma 180 Brazilian...
Abstract Dengue fever is a viral condition that has become recurrent issue for public health in tropical countries, common endemic areas. Although structure and composition have been widely studied, the infection phenotype terms of small molecules remains poorly established. This contribution providing comprehensive overview metabolic implications virus-host interaction using lipidomic-based approach through direct-infusion high-resolution mass spectrometry. Our results provide further...
Recent Zika outbreaks in South America, accompanied by unexpectedly severe clinical complications have brought much interest fast and reliable screening methods for ZIKV (Zika virus) identification. Reverse-transcriptase polymerase chain reaction (RT-PCR) is currently the method of choice to detect biological samples. This approach, nonetheless, demands a considerable amount time resources such as kits reagents that, endemic areas, may result substantial financial burden over affected...
Abstract The increase of Zika virus (ZIKV) infections in Brazil the last two years leaves a prophylactic measures on alert for this new and emerging pathogen. Concerning our positive experience, we developed prototype using Neisseria meningitidis outer membrane vesicles (OMV) ZIKV cell growth fusion OMV envelope particles. nanoparticles resulting from N . with infected C6/36 cells line were analyzed by Nano tracking analysis (NTA), zeta potential, differential light scattering (DLS), scan...
Follicular fluid (FF) protects the oocyte against proteolysis and extrusion during ovulation, providing an appropriate microenvironment that favors proper embryonic development; thereby, FF plays a key role in embryo quality. Being directly related to cattle breeding, studying is extremely important livestock science measure fertility. This may eventually help assess quality of both meat milk, products widely consumed worldwide. There commercial interest evaluation characterization compounds...
Abstract Zika virus (ZIKV) has emerged as one of the most medically relevant viral infections past decades; devastating effects this over developing brain are a major matter concern during pregnancy. Although connection with congenital malformations well documented, mechanisms by which ZIKV reach central nervous system (CNS) and causes impaired cortical growth in affected fetuses need to be better addressed. We performed non-invasive, metabolomics-based screening saliva from infants syndrome...
Abstract Aspergillus carbonarius and niger are the main responsible fungi for accumulation of ochratoxin A (OTA) in wine grapes. Some strains able to convert parent mycotoxin into other compounds by means hydrolysis and/or conjugation reactions through their defense mechanisms enzymatic activity, leading formation a modified mycotoxin. Thus, variability growth metabolite production inherent strain, occurring distinctively even when submitted similar conditions. In this sense, contribution...
Cystic fibrosis (CF) is a disabling genetic disease with an increased prevalence in European heritage populations. Currently, the most used technique for collection of CF samples and diagnosis provided through uncomfortable tests, uncertain results, mostly based on chloride concentration sweat. Since mutation induces many metabolic changes patients, exploring these alterations might be alternative to visualize potential biomarkers that could as interesting tools further diagnostic upgrade,...
Abstract Recently, microcephaly cases have increased in Americas and been matter of concern due to Zika virus (ZIKV) recent outbreak. Previous studies shown that ZIKV‐infected progenitor neuronal cells present morphological abnormalities rates cell death, which may be indicators causes. As indicate ZIKV' tropism for brain cells, how would a glioblastoma (GBM) lineage behave under ZIKV infection, considering GBM the most common malignant tumor adults, presenting extreme chemoresistance high...
The eukaryotic translation initiation factor 5A (eIF5A) is widespread in Archaea and Eukarya contains the unusual amino acid residue hypusine. Recent studies have shown its involvement elongation step of translation. More specifically, acting on synthesis proteins containing polyproline stretches. eIF5A has been involved different physiological pathological processes, such as inflammation, cancer, diabetes virus infection. In humans, transcript variants related to eIF5A1 are currently...
Infertility is a worldwide concern, affecting one in six couples throughout their reproductive period. Therefore, enhancing the clinical tools available to identify causes of infertility may save time, money, and emotional distress for involved parties. This study aims annotate potential biomarkers follicular fluid that are negatively pregnancy outcomes women suffering infertility-related diseases such as endometriosis, tuboperitoneal factor, uterine unexplained infertility, using...
Zika virus (ZIKV) has recently become a major matter of concern since its association with microcephaly cases in newborns was determined. From then on, ZIKV been untiringly studied, and several scientific data have shown the virus' tropism to neural cells. Previous studies proposed that induced glioblastoma cells death, suggesting ZIKV-associated molecules might induce intracellular biochemical alterations, thereby be alternatives for cancer management. In this sense, present contribution...
Abstract The recent outbreak of Zika virus (ZIKV) infection associated with microcephaly cases has elicited much research on the mechanisms involved in ZIKV-host cell interactions. It been described that impairs growth, raising a hypothesis about its oncolytic potential against cancer cells. ZIKV tumor growth inhibition was later confirmed for glioblastoma. also demonstrated an inactivated prototype (ZVp) based bacterial outer membrane vesicles antiproliferative activity upon other lines,...
Cachaça is a popular spirit produced in Brazil, obtained by distillation of fermented sugar cane. Among the contaminants arising from production, ethyl carbamate carcinogenic compound that occurs naturally foods and beverages; maximum limit established current legislation 150 µg L-1. Quality control usually performed using gas chromatography; however, robustness reproducibility quantitative results may be severely impaired, as addition 6-30 g L-1 sucrose common procedure for taste...
ABSTRACT Recently, microcephaly cases have increased in Americas and been matter of concern due to Zika virus (ZIKV) recent outbreak. Previous studies shown that ZIKV-infected progenitor neuronal cells present morphological abnormalities rates cell death, which may be indicators causes. As indicate virus’ tropism for brain cells, how would a glioblastoma (GBM) lineage behave under ZIKV infection, considering GBM the most common malignant tumor adults, presenting extreme chemoresistance high...