- Leprosy Research and Treatment
- Mosquito-borne diseases and control
- Rabies epidemiology and control
- Health, Nursing, Elderly Care
- Global Maternal and Child Health
- Parasites and Host Interactions
- Zoonotic diseases and public health
- Malaria Research and Control
- Viral Infections and Vectors
- Research on Leishmaniasis Studies
- Dermatological diseases and infestations
- HIV/AIDS Research and Interventions
- Trypanosoma species research and implications
- Yersinia bacterium, plague, ectoparasites research
- Tuberculosis Research and Epidemiology
- Poxvirus research and outbreaks
- Maternal and Neonatal Healthcare
- Youth, Drugs, and Violence
- Vector-borne infectious diseases
- Fungal Infections and Studies
- Hematological disorders and diagnostics
- Mycobacterium research and diagnosis
- Viral Infections and Outbreaks Research
- Insect Pest Control Strategies
- Complementary and Alternative Medicine Studies
Universidade Federal do Ceará
2016-2025
Centro de Estudos e Pesquisa em Saúde Coletiva
2024
Universidade Estadual de Maringá
2018
Fundação de Apoio a Pesquisa do Estado de Goiás
2018
Australian Institute of Tropical Health and Medicine
2014-2015
James Cook University
2014-2015
Instituto Federal de Educação, Ciência e Tecnologia do Ceará
2015
University of Basel
2012-2014
Swiss Tropical and Public Health Institute
2012-2014
United Food and Commercial Workers
2011-2013
Zika virus (ZIKV) infection is spreading rapidly within the Americas after originating from an outbreak in Brazil. We describe current ZIKV epidemic Brazil and neurological symptoms arising. First cases of acute exanthematic disease were reported Brazil's Northeast region at end 2014. In March 2015, autochthonous was determined to be causative agent disease. As syndromes regions where ZIKV, dengue and/or Chikungunya viruses co-circulate reported, also identified cerebrospinal fluid patients...
Visceral leishmaniasis (VL) is a significant public health problem in Brazil and several regions of the world. This study investigated magnitude, temporal trends spatial distribution mortality related to VL Brazil.We performed based on secondary data obtained from Brazilian Mortality Information System. We included all deaths 2000 2011, which was recorded as cause death. present epidemiological characteristics, trend analysis case fatality rates by joinpoint regression models, using...
Objective To describe mortality from neglected tropical diseases (NTDs) in Brazil, 2000-2011.Methods We extracted information on cause of death, age, sex, ethnicity and place residence the nationwide system at Brazilian Ministry Health.We selected deaths which underlying death was a disease (NTD), as defined by World Health Organization (WHO) based its International statistical classification related health problems, 10th revision (ICD-10) codes.For specific NTDs, we estimated crude...
Background Aedes aegypti and albopictus perform an important role in the transmission of dengue virus to human populations, particularly tropical subtropical regions world. Despite a lack understanding relation maintenance nature during interepidemic periods, vertical populations A. appears be significance urban scenario Fortaleza. Methods From March 2007 July 2009 collections larvae pupae spp were carried out 40 neighborhoods The yielded 3,417 (91%) mosquitoes 336 (9%) mosquitoes. Only...
OBJECTIVE To analyze, stratifield by gender, trends of the new case leprosy detection rates in general population and children; grade 2 disability, proportion multibacillary cases, state Bahia, Brazil from 2001 to 2014. METHODS A time series study based on data National Information System for Notifiable Diseases. The trend analysis included Poisson regression models infection points (Joinpoint) stratified gender. RESULTS There was a total 40,054 cases with downward overall rate (Average...
Background Chagas' disease is an important neglected public health problem in many Latin American countries, but population-based epidemiological data are scarce. Here we present a nationwide analysis on Chagas-associated mortality, and risk factors for death from this disease. Methodology/Principal Findings We analyzed all certificates of individuals who died between 1999 2007 Brazil, based the Mortality Information System (a total 243 sets with about 9 million entries). was mentioned...
We determined the seroprevalence of Toxoplasma gondii and associated risk factors among 963 pregnant women attending an obstetric hospital in Fortaleza, Brazil. Seroprevalences IgG IgM against T. were 68.6% (95% confidence interval [CI] = 65.6–71.6%) 0.5% CI 0.06–1.0%), respectively. Seroprevalence was high less than 25 years age (91.7%) low-income (odds Ratio [OR] 1.40, 95% 1.02–1.90). Multivariate regression analysis showed that consumption homemade water ice (adjusted OR 1.49, 1.09–2.04),...
Abstract Background Chikungunya virus (CHIKV) emerged in the Americas 2013 and has caused approximately 2.1 million cases >600 deaths. A retrospective investigation was undertaken to describe clinical, epidemiological, viral genomic features associated with deaths by CHIKV Ceará state, northeast Brazil. Methods Sera, cerebrospinal fluid (CSF), tissue samples from 100 fatal suspected arbovirus infection were tested for CHIKV, dengue (DENV), Zika (ZIKV). Clinical, death reports obtained...
Chronic sequelae and disabilities are one of the main problems in leprosy. The current study aimed to estimate prevalence leprosy patients after successfully completing multidrug therapy Araguaína, Tocantins State, Brazil. This was a cross-sectional including 282 cases diagnosed from 2004 2009. degrees disability at diagnosis discharge treatment were collected medical records National Information System for Notifiable Diseases (SINAN). A simplified neurological workup performed treatment....
Abstract Objective The Brazilian National Hansen’s Disease Control Program recently identified clusters with high disease transmission. Herein, we present different spatial analytical approaches to define highly vulnerable areas in one of these clusters. Method study area included 373 municipalities the four states Maranhão, Pará, Tocantins and Piauí. Spatial analysis was based on as observation unit, considering following indicators: (i) rate new cases/100 000 population, (ii) cases <15...
Tocantins State in north Brazil remains endemic for leprosy, with high detection rates and occurrence of disabilities at diagnosis. We analyzed trends identified factors associated the disability diagnosis.We data from Notifiable Diseases Information System (SINAN). included new leprosy cases resident Tocantins, diagnosed between 2001 2012.During study period, there were 14,532 residing Tocantins. Of these, 12,328 (84.9%) assessed degree diagnosis: 9,166 (74.4%) Grade 0; 2,498 (20.3%) 1; 664...
To describe patterns of spatial distribution mortality associated with Chagas' disease in Brazil.Nationwide study all deaths Brazil from 1999 to 2007, where was recorded as a cause death. Data were obtained the national Mortality Information System Ministry Health. We calculated mean rate for each municipality residence three-year intervals and entire period. Empirical Bayes smoothing used minimise random variation rates because population size municipalities. evaluate existence...
ABSTRACT OBJECTIVE To describe the spatial patterns of leprosy in Brazilian state Tocantins. METHODS This study was based on morbidity data obtained from Sistema de Informações Agravos Notificação (SINAN – Notifiable Diseases Information System), Ministry Health. All new cases individuals residing Tocantins, between 2001 and 2012, were included. In addition to description general disease indicators, a descriptive analysis, empirical Bayesian analysis dependence performed by means global...
INTRODUCTION: Neural damages are among the main factors that contribute to physical disability in leprosy. Systematic monitoring using a broad physical, psychological and social approach is necessary. OBJECTIVE: The objective of this study was characterize limitation activity participation its correlation with disabilities and/or impairment individuals after being discharged from multidrug leprosy therapy. METHOD: A cross-sectional conducted Araguaína, state Tocantins, which hyperendemic...
We analysed nationwide trends and spatial distribution of NTD-related mortality in Brazil. included all death certificates Brazil from 2000 to 2011, which NTDs were recorded as any causes death. A total 100,814/12,491,280 (0.81%) identified, mentioned at least one NTD. Age-adjusted rates showed a significant decrease over time (annual percent change [APC]: − 2.1%; 95% CI: 2.8 1.3), with decreasing the Southeast, South, Central-West regions, stability Northeast region, increase North region....
Since the end of 2014, Zika virus (ZIKV) infection has been rapidly spreading in Brazil.To analyze possible association yellow fever vaccine with a protective effect against ZIKV-related microcephaly, following spatial analyses were performed, using Brazilian municipalities as units: i) vaccination coverage individuals aged 15-49; ii) reported cases microcephaly by municipality; and iii) confirmed related to ZIKV, municipality. SaTScan software was used identify clusters for high risk...
To identify the socioeconomic, demographic, operational, and health service-related factors associated with occurrence of leprosy in a hyperendemic State North Brazil.
INTRODUCTION Chikungunya causes fever and severe persistent joint pain. METHODS We reported a chikungunya outbreak that occurred in Ceará State, Brazil between 2016 2017 with emphasis on epidemiological characterization of cases, high number deaths, mortality-associated factors, spatial temporal spread the epidemic among municipalities. RESULTS: In November 2015, first autochthonous cases were confirmed Ceará, Brazil. 2016-2017, 195,993 reported, an incidence 2,186.5/100,000 inhabitants 244...
In Brazil, the SARS-CoV-2 vaccination program has so far prioritized people over 75 years of age. By end March 2021, in Ceará State, a total 313,328 elderly had received at least one dose vaccine (45% Oxford-AstraZeneca/Fiocruz and 55% CoronaVac-Sinovac/Butantan), 159,970 two doses (83% CoronaVac-Sinovac/Butantan 17% Oxford-AstraZeneca/Fiocruz). After single dose, there was already significant reduction COVID 19-related deaths (protection ratio: 19.31 (95% CI: 18.20–20.48), attributable...
Background Low adherence to multidrug therapy against leprosy (MDT) is still an important obstacle of disease control, and may lead remaining sources infection, incomplete cure, irreversible complications, resistance. Methodology/Principal Finding We performed a population-based study in 78 municipalities Tocantins State, central Brazil, applied structured questionnaires on leprosy-affected individuals. used two outcomes for assessment risk factors: defaulting (not presenting health care...