Aditi Sharma

ORCID: 0000-0001-6518-5745
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About
Contact & Profiles
Research Areas
  • Neurobiology and Insect Physiology Research
  • Developmental Biology and Gene Regulation
  • Hippo pathway signaling and YAP/TAZ
  • Immune Cell Function and Interaction
  • Eosinophilic Disorders and Syndromes
  • Asthma and respiratory diseases
  • FOXO transcription factor regulation
  • Genetics, Aging, and Longevity in Model Organisms
  • Silkworms and Sericulture Research
  • Invertebrate Immune Response Mechanisms
  • Insect and Pesticide Research
  • Silk-based biomaterials and applications
  • Genetics and Physical Performance

Columbia University
2021-2024

Indian Institute of Science Education and Research Kolkata
2015-2018

Indian Institute of Science Education and Research Pune
2017

Dayton VA Medical Center
1993

Group cell migration is a highly coordinated process, involved in number of physiological events such as morphogenesis, wound healing and tumor metastasis. Unlike single cells, collectively moving cells are physically attached to each other retain some degree apical-basal polarity during the migratory phase. Though much known about direction sensing, it far from clear how regulated diverse instances multicellular movement. Here we report role dPak3, group I p21 activated serine-threonine...

10.1242/dev.125682 article EN Development 2015-01-01

As collective cell migration is intimately involved in different aspects of metazoan development, molecular mechanisms underlying this process are being explored a variety developmental contexts. Border (BC) during

10.1242/dev.166165 article EN Development 2018-06-27

Numerous factors have been implicated in the cell-cell interactions that lead to elimination of cells via cell competition, a context-dependent process selection somatic tissues is based on comparisons cellular fitness. Here, we use series genetic tests Drosophila explore relative contribution pleiotropic cytokine tumor necrosis factor α (TNFα) Myc-mediated competition (also known as Myc supercompetition or competition). We find sole TNF, Eiger (Egr), its receptor Grindelwald (Grnd/TNF...

10.1093/genetics/iyae107 article EN cc-by Genetics 2024-07-10

10.1016/j.cbpa.2007.01.167 article EN Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology 2007-04-01

Group cell migration is a highly coordinated process that involved in number of physiological events such as morphogenesis, wound healing and tumor metastasis. Unlike single cells, collectively moving cells are physically attached to each other retain some degree apical-basal polarity during the migratory phase. Although much known about direction sensing, how regulated multicellular movement remains unclear. Here we report role protein kinase Pak3 maintaining migrating border clusters...

10.1242/jcs.182980 article EN Journal of Cell Science 2015-11-15

Abstract Numerous factors have been implicated in the cell-cell interactions that lead to elimination of cells via cell competition, a context-dependent process selection somatic tissues is based on comparisons cellular fitness. Here we use series genetic tests Drosophila explore relative contribution pleiotropic cytokine Tumor Necrosis Factor ⍺ (TNF⍺) Myc-mediated competition (also known as Myc super-competition or competition). We find sole TNF, Eiger (Egr), its receptor Grindelwald...

10.1101/2021.04.06.438672 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-04-06
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