Tumor‑associated macrophages (TAMs) often assume an immunoregulatory M2 phenotype. Thus, the aim of present study was to clarify correlation vascularity and TAMs, in particular phenotype stroma tumor areas, with clinical pathological outcomes patients bladder cancer. The TAM counts microvessel (MVCs) were determined immunohistochemically 21 number infiltrating TAMs measured using immunohistochemistry anti‑cluster differentiation (CD)68 anti‑CD163 antibodies, identify a macrophage lineage...

Since fibrosis is observed in smokers’ gingiva, it was hypothesized that caused by nicotine the periodontium. Therefore, this study, we investigated effects of on induction a profibrotic molecule, connective tissue growth factor (CCN2/CTGF), human gingival fibroblasts (HGFs) and periodontal ligament (PDL) cells. With 1 μg/mL nicotine, vacuolization attenuated proliferation were observed. Interestingly, increased production CCN2/CTGF protein both cells without increasing mRNA expression....

Gastric xanthomas are frequently observed in the stomach as small yellowish plaques or nodules. A close relationship among Helicobacter pylori infection, atrophic gastritis, and has been reported. We assessed clinicopathological features of gastric cancer with without xanthomas.A total 91 patients who were diagnosed having early enrolled. evaluated gastritis status using scores for atrophy, positivity H. prevalence rate xanthomas, cancer.Gastric 72.5% cases. Scores atrophy significantly...

Background and Purpose: The usefulness of posterior rhabdosphincter reconstruction (PR) during robot-assisted radical prostatectomy (RARP) has still been controversial. We investigated the association several factors, including Rocco original double-layered PR, with early recovery urinary continence after RARP. Patients Methods: Between August 2006 April 2011, a single surgeon at Tokyo Medical University Hospital performed 206 RARPs. Of these patients, 199 eligible patients were enrolled in...

Nodular gastritis (NG) is defined as antral with endoscopic findings usually characterized by a miliary pattern resembling "goose flesh." There possible association between NG and gastric cancer. The aim of our study to investigate whether there are some differences young elderly people in incidence characteristics estimate potential risk factors for cancer adults NG.Patients underwent upper gastrointestinal endoscopy abdominal symptoms or screening. Incidence rates relationship an group (40...

Background and Objective: Connective tissue growth factor (CCN2/CTGF) plays an important role in wound healing regulation of the extracellular matrix periodontal tissue. However, functional relationship between altered transforming factor‐beta1 levels CCN2/CTGF has not been extensively investigated human gingival fibroblasts ligament cells. This study effects on expression gene cells vitro . Material Methods: Cells were isolated from normal tissues cultured Dulbecco’s modified Eagle’s...

Abstract A new bis( o ‐aminophenol) with a crank and twisted noncoplanar structure ether linkages, 2,2′‐bis(4‐amino‐3‐hydroxyphenoxy)biphenyl, was synthesized by the reaction of 2‐benzyloxy‐4‐fluoronitrobenzene biphenyl‐2,2′‐diol, followed reduction. Biphenyl‐2,2′‐diyl‐containing aromatic poly(ether benzoxazole)s inherent viscosities 0.52–1.01 dL/g were obtained conventional two‐step procedure involving polycondensation monomer various dicarboxylic acid chlorides, yielding precursor...

With the advent of serum prostate-specific antigen (PSA), a larger number prostate cancers in early phase have been successfully detected. Although decisions to perform biopsies are routinely based on PSA levels, level is easily influenced by benign prostatic hyperplasia, with poor specificity. Therefore, aim present study was assess clinical significance doubling time (PSADT) prior and following radical prostatectomy. In total, 488 patients T1c-3N0M0 cancer who underwent prostatectomy were...

Hepatic portal venous gas (HPVG) was detected by CT in a 64-year-old woman who suddenly complained of lower abdominal pain. However, the symptoms disappeared rapidly, and gastrointestinal endoscopy indicated only terminal ileitis. Conservative treatment alone performed, HPVG completely approximately 18 hours later. The use proved to be useful for following course HPVG.(Internal Medicine 41: 950-952, 2002)

Endoclip migration into the common bile duct following laparoscopic cholecystectomy (LC) is an extremely rare complication. Migrated endoclip can cause obstruction, serve as a nidus for stone formation, and cholangitis. We report case of cholangitis due to migrated consequent choledocholithiasis 6 years after LC, which was successfully treated by endoscopic extraction.

Although urolithiasis is considered to be strongly associated with lifestyle habits, there are numerous cases in which develops despite a non-obese body type or healthy habits. However, clinical practice, the diet therapy and changes instructed for prevention of recurrence almost identical cases. Therefore, present study examined effect mass index (BMI) on its surrounding environment patients, by analyzing number normal- high-BMI (healthy overweight) patients urolithiasis. The analyzed 63...

The salivary gland duct ligation model for the treatment of obstruction caused by stones causes hypofunction gland.However, sufficient results have not been obtained regarding regeneration acinar cells and restoration function, development methods is still ongoing.Here, we administered dental pulp stem cell-derived conditioned medium (DPSC-CM) containing various growth factors to mice examined its effects.The main excretory submandibular was ligated; after 3 weeks, released, Dulbecco's...

Presacral myelolipomas are rare, benign, asymptomatic tumors composed of mature adipose tissue and hematopoietic elements, but fewer than 50 cases have been reported in the literature. They usually discovered incidentally during imaging studies often misdiagnosed as liposarcoma, which a malignant nature, because findings myelolipoma can be similar to those liposarcoma. It is challenging distinguish presacral from other fat-containing without performing histological examination. We should...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry of cyclic phosphorus compounds. 4. Syntheses the sex pheromone from pedal gland bontebok and some 1,4-diketones by use 1,1-diphenylphospholanium perchlorateTetsuya Fujimoto, Yukihiko Hotei, Hisashi Takeuchi, Satoshi Tanaka, Kazuchika Ohta, Iwao YamamotoCite this: J. Org. Chem. 1991, 56, 15, 4799–4802Publication Date (Print):July 1, 1991Publication History Published online1 May 2002Published inissue 1 July...

A 65-year-old male visited us with complaints of retarded urination, dysuria, gross hematuria, and fever. Urinalysis showed pyuria. Prostatic tumor lung metastasis was suspected from computed tomography magnetic resonance imaging. Transurethral prostatic biopsy bronchoscopic only revealed fibrinoid necrosis inflammatory infiltration. Right lateral maxillary sinusitis also found by MRI. ANCA testing positive specificity for anti-PR3 (PR3-ANCA). On the basis these results, Granulomatosis...

A 69-year-old man was referred to our hospital with chief complaints of urinary incontinence, pollakiuria, thin stools and edema the left lower extremity. Computed tomography magnetic resonance imaging revealed bilateral hydronephrosis, thickening rectal posterolateral bladder walls, enlargement obturator lymph nodes, suggesting metastasis. The carcinoembryonic antigen carbohydrate 19-9 levels were 5.6 ng/ml 460.1 U/ml, respectively. transurethral biopsy grade 2 urothelial carcinoma...

An ether-containing bis(o-aminophenol) monomer having a bulky diphenylfluorene unit, 9, 9-bis[4-(4-amino-3-hydroxyphenoxy)phenyl]fluorene, was synthesized by the reaction of 9-bis(4-hydroxyphenyl)fluorene with 2-benzyloxy-4-fluoronitrobenzene giving bis-nitrobenzene compound, followed catalytic reduction. Diphenylfluorene-containing aromatic poly(ether benzoxazole)s (PEBOs) inherent viscosities 0.57-0.74 dl g-1 were obtained in two steps polycondensation bis(oaminophenol) various...