A5037114866- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Sepsis Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Health Policy Implementation Science
- Patient-Provider Communication in Healthcare
- Breast Implant and Reconstruction
- Mental Health and Patient Involvement
- Cardiac, Anesthesia and Surgical Outcomes
- Disaster Response and Management
- Cancer Genomics and Diagnostics
- Clinical practice guidelines implementation
- Radiomics and Machine Learning in Medical Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hip and Femur Fractures
- Traumatic Brain Injury and Neurovascular Disturbances
- Frailty in Older Adults
- Ethics in Clinical Research
- Injury Epidemiology and Prevention
- Cardiac Imaging and Diagnostics
- Hospital Admissions and Outcomes
- Acute Myocardial Infarction Research
The Patients Association
2022-2023
University of Warwick
2013-2022
Heart of England NHS Foundation Trust
2013-2019
Introduction Reducing premature death is a key priority for the UK National Health Service (NHS). NHS Ambulance services treat approximately 30 000 cases of suspected cardiac arrest each year but survival rates vary. The British Heart Foundation and Resuscitation Council (UK) have funded structured research programme—the Out Hospital Cardiac Arrest Outcomes (OHCAO) programme. aim project to establish epidemiology outcome OHCA, explore sources variation in feasibility setting up national OHCA...
Active patient engagement is increasingly viewed as essential to ensuring that patient-driven perspectives are considered throughout the research process. However, guidance for (PE) in HRQoL does not exist, evidence-base practice limited, and we know relatively little about underpinning values can impact on PE practice. This first study explore should underpin contemporary help inform future good guidance.
The diagnosis, management and prognosis of microinvasive breast carcinoma remain controversial.We analysed the outcomes patients with DCIS without microinvasion diagnosed between 2003 2012 within Sloane project.Microinvasion was recorded in 521 11,285 (4.6%), considerable variation reported incidence among screening units (0-25%). Microinvasion associated high-grade DCIS, larger size, comedo necrosis solid, cribriform architecture (all P < 0.001). more frequent who underwent mastectomy...
Abstract Background The LOw RISk DCIS (LORIS) study was set up to compare conventional surgical treatment with active monitoring in women ductal carcinoma situ (DCIS). Recruitment trials a surveillance arm is known be challenging, so strategies maximise patient recruitment, aimed at both patients and recruiting centres, were implemented. Methods Women aged ≥ 46 years histologically confirmed diagnosis of non-high-grade eligible for 1:1 randomisation either surgery or monitoring. Prior...
With ever increasing concern over ambulance handover delays this paper looks at the impact of dedicated A&E nurses for handovers and effect it can have on waiting times. It demonstrates that although such roles bring about reduced times, also suggests using as a sole method to achieve these targets would require unacceptably low staff utilisation.
Objectives The Out-of-Hospital Cardiac Arrest Outcomes (OHCAO) project aims to understand the epidemiology and outcomes of out-of-hospital cardiac arrest (OHCA) across UK. This data linkage study is a subproject OHCAO. aim was establish feasibility linking OHCAO National Health Service (NHS) patient demographic Office for Statistics (ONS) date death held on NHS Personal Demographics (PDS) database improve quality enable analysis 30-day survival from OHCA. Design setting Data were collected 1...
Objectives There is considerable interest in reducing the cost of clinical trials. Linkage trial data to administrative datasets and disease-specific registries may improve efficiency, but it has not been reported resuscitation trials conducted UK. To assess feasibility using national follow up patients transported hospital following attempted a cluster randomised mechanical chest compression device out-of-hospital cardiac arrest. Methods Hospital on participants were requested from Episode...
Breast Cancer Research 25(S1): O1As a unit, we implemented wireless image transfer from our Screening Mobile van in 2016, which resulted some reduction paper usage (only printing Client forms for those attending).However, the suspension of at start pandemic enabled us to undertake multidisciplinary (radiological, radiographic and especially administrative) in-depth assessment existing pathway design an equivalent electronic pathway, entirely without screen result.Redundant/duplicated...
Abstract Background The variable natural history of ductal carcinoma in situ (DCIS) is poorly understood. aim this retrospective cohort study was to determine the outcomes women who were diagnosed through English National Health Service Breast Screening Programme (NHS BSP) and had no surgery for screen-detected DCIS. Method NHS BSP databases searched with DCIS without invasive cancer on needle biopsy between 1 April 2001 31 March 2018 inclusive, record within 6 months diagnosis. These...
Abstract Background: Disparity between mammographic and pathological sizing of DCIS can lead to surgical overtreatment, with poor cosmetic outcomes breast conservation surgery (BCS) or inappropriate mastectomy versus undertreatment, subsequent need for re-excision. In addition, where size is smaller than size, this may reflect an increased risk mammographically occult residual disease post surgery; there a possibility underestimation missed positive margins, both scenarios resulting in...
Abstract Background/objectives The natural history of microinvasive carcinoma the breast (one or more foci invasion 1mm less) and its optimal management remain controversial. We analysed frequency outcome patients with DCIS plus microinvasion within a large prospective cohort screen-detected DCIS. Methods Patients diagnosed between 2003 2012 without in final surgical specimen were identified from UK Sloane Project database. Comprehensive imaging, surgical, pathology, oncology subsequent data...