A5078014961- Head and Neck Cancer Studies
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Oral and Maxillofacial Pathology
- Reconstructive Facial Surgery Techniques
- Tracheal and airway disorders
- Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
- Oral Health Pathology and Treatment
- Pharmaceutical studies and practices
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Antibiotics Pharmacokinetics and Efficacy
- Sinusitis and nasal conditions
- Cleft Lip and Palate Research
- Analytical Methods in Pharmaceuticals
- Neuroendocrine Tumor Research Advances
- Oral health in cancer treatment
- Pancreatic and Hepatic Oncology Research
- Cancer-related gene regulation
- Streptococcal Infections and Treatments
- Acute Myocardial Infarction Research
- Oral and gingival health research
Shaukat Khanum Memorial Cancer Hospital and Research Center
2016-2025
Foundation University Islamabad
2025
Mulawarman University
2024
Hamdard University
2024
National University of Computer and Emerging Sciences
2024
Barmherzige Schwestern Krankenhaus Wien
2022
McMaster University
2022
Baqai Medical University
2022
Khwaja Yunus Ali Medical College
2018-2021
Heinrich Heine University Düsseldorf
2019-2021
The new AJCC staging system (8th edition) incorporates depth of invasion to stage oral cancers. It is a recognized predictor for neck nodal metastasis and local recurrence, the associated risk not well defined. aim this study was explore occult recurrence in relation early squamous cell carcinoma tongue.We have evaluated records 179 patients with tongue cancer treated our unit from 2006-2015 mean age 57.92 ± 11.93 years. Treatment modalities used were surgery (26%), followed by radiotherapy...
Objective To assess the epidemiology of traumatic humeral shaft fracture in chittagong. Methodology This observational study was carried out at Department Orthopedic Surgery Chittagong Medical College Hospital, Chattogram from August 2019 to July 2021. All adult patients closed diaphyseal humerus attending Orthopaedics department, college Hospital during period were population. Purposive sampling done according availability patients. data compiled and sorted properly quantitative analyzed...
ABSTRACT Background This study investigates oral cavity squamous cell carcinoma (OSCC) among Afghan patients treated at a Pakistani cancer center, focusing on epidemiology, tumor characteristics, outcomes, and healthcare challenges faced by from conflict‐affected regions. Methods A retrospective analysis of OSCC (2010–2023) was conducted. Demographic, clinical, treatment data were evaluated, with survival outcomes analyzed using Kaplan–Meier analysis. Results Of the 117 patients, 47.1% had...
The submental flap provides an alternative technique in orofacial reconstruction, especially situations where free services are not available. objective of this study is to demonstrate the oncological safety and benefits oral cavity reconstruction a tertiary care cancer hospital.A total 27 patients with cancers, which underwent from 2015 2017 at Shaukat Khanum Cancer Memorial Hospital, were included study. We have retrospectively reviewed records these patients.There 25 male 2 female age...
Adnexal tumors of the skin are a large and diverse group benign malignant neoplasms, which exhibit morphological differentiation toward one different types adnexal epithelium present in normal they pose diagnostic challenge. The purpose this study is to share our experience with these rare but aggressive at tertiary care cancer hospital developing country. A retrospective review 11 patients diagnosed their variants from January 2005 December 2014, treated either surgically or non-surgically,...
(1) Objective: To evaluate long-term functional outcome in patients who underwent primary or salvage total laryngectomy (TL), TL with partial (TLPP), pharyngectomy (TLTP), and to establish a new scoring system predict complication rate outcome; (2) Material Methods: Between 1993 2019, 258 (n = 85), TLPP 101), TLTP 72). Based on the extent of tumor resection, all were stratified (i) localization I: TL; II: TLPP; III: (ii) surgical treatment (A: resection; B: surgery). Type outcome, including...
Objective To evaluate clinical outcome of low (G1), intermediate (G2), and high‐(G3) grade mucoepidermoid carcinomas (MEC) the parotid gland. Study Design Retrospective chart review including 212 patients. Clinicopathological data was statistically analyzed regarding grading, overall survival (OS), disease‐free (DFS) disease‐specific (DSS). Results 105 (49.5%) G1, 73 (34.5%) G2, 34 (16%) G3 MEC were included 56 (26.4%) patients presented with neck node metastases. The risk occult nodal...
Abstract Background Early laryngeal cancer treated with definitive radiotherapy or surgery has a high cure rate. This study evaluated the patterns of treatment failure and long-term results early cancers radiotherapy. Method From January 2002 to December 2014, total 242 patients early-stage were radical Results All had squamous cell carcinoma larynx (92 per cent male 8 female). Median follow-up was 4.5 years. The majority smokers (57.4 cent). Local seen in 12.5 stage I 22.8 II patients....
Background Salivary gland tumors are rare salivary malignancies with resemblance to ductal breast carcinoma. We have described clinicopathological behavior and treatment outcomes of this malignancy. Methods duct carcinoma patients treated from 2010 2015 were retrospectively analyzed for characteristics treatment-related the disease. Results A total 12 included in study. All males mean age 52.58 ± 13.43. Parotid was most commonly involved major while buccal mucosa anterior tongue common oral...
Abstract Background Oral sub mucous fibrosis is a rare chronic, progressive, pre malignant collagen disorder of oral mucosa in people Asian descent characterized by trismus, blanching and stiffness mucosa, burning sensation mouth hypomobility soft palate tongue with loss gustatory sensation. Betel nut chewing the most common etiological agent. Surgery remains main stay severe cases aims at release fibrotic bands resurfacing raw areas different options. Reconstruction can be done using...
Comparative pharmacokinetic (PK) data analysis of drugs administered using developed child-appropriate and market authorized dosage formulation is sparse important in pediatric drug development.To compare evaluate any differences PK enalapril two treatments orodispersible minitablets (ODMTs) reference tablet (Renitec®) compartment model validated least square minimization method (LSMM) parameter estimation.Full profile sets were obtained from a phase I clinical trial, whereby three...
Synovial sarcoma (SS) accounts for 10-15 percent of adult soft tissue sarcomas. Transducin-like enhancer split 1 (TLE1), a transcriptional repressor, is essential in hematopoiesis, neuronal differentiation, and terminal epithelial differentiation. TLE1 proteins inhibit Wnt signaling other cell fate determination signals, so have an established role repressing has recently been shown to be highly sensitive relatively specific marker SS.Study design retrospective, descriptive. A total 25 cases...
Purpose: Enalapril has an established safety and efficacy in adults is used hypertension, heart failure, renal failure. In pediatric patients, enalapril labeled for children with hypertension off label The systematic literature search aims to assess the current knowledge about its active metabolite enalaprilat pharmacokinetics as a basis dose delineation patients Methods: A review was performed PubMed database using relevant keywords. Dose normalization of pharmacokinetic parameters...
Sinonasal malignancies (SNMs) are a rare and heterogeneous group of cancers with an incidence 3%-5% all head-and-neck tumours. The aim the present study was to identify characteristic features SNMs analyze treatment outcomes prognostic factors affecting it.A retrospective review patients SNM treated at dedicated cancer center Pakistan between 2004 2018 carried out. All histologically proven diagnosis malignancy arising from nasal cavity or paranasal sinuses being curative intent were...