Josua Markus

ORCID: 0000-0001-6567-1241
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Ginseng Biological Effects and Applications
  • Phytochemistry and Bioactivity Studies
  • Medicinal Plants and Neuroprotection
  • Pharmacological Effects of Natural Compounds
  • Advanced Nanomaterials in Catalysis
  • melanin and skin pigmentation
  • Biochemical Analysis and Sensing Techniques
  • Supercapacitor Materials and Fabrication
  • Graphene and Nanomaterials Applications
  • Electrocatalysts for Energy Conversion
  • Moringa oleifera research and applications
  • Biochemical and Structural Characterization
  • Plant tissue culture and regeneration
  • Salivary Gland Disorders and Functions
  • Calcium Carbonate Crystallization and Inhibition
  • Water and Wastewater Treatment
  • Nanofabrication and Lithography Techniques
  • Pharmacology and Nanomedicine Research
  • Phytochemistry and Biological Activities
  • Gut microbiota and health
  • Microbial Metabolism and Applications
  • Essential Oils and Antimicrobial Activity
  • Conducting polymers and applications
  • Thermal and Kinetic Analysis

The University of Queensland
2023-2025

Institute of Bioengineering and Nanotechnology
2025

Kyung Hee University
2016-2019

Life University
2019

Yong In University
2019

Government of the Republic of Korea
2019

Council for Scientific and Industrial Research
1952

Gold (FA-AuNps) and silver (FA-AgNps) nanoparticles were synthesized at room temperature by aqueous extract of dried fruits Amomum villosum, also known as Fructus Amomi (cardamom), in order to confer antioxidant, catalytic, antimicrobial activities treatment effect against breast cancer cells. Fruit extracts served both reducing agents stabilizers lieu chemical agents. Ultra-violet visible (UV-Vis) spectroscopy, field emission transmission electron microscopy (FE-TEM), energy-dispersive...

10.1080/21691401.2017.1296849 article EN Artificial Cells Nanomedicine and Biotechnology 2017-03-14

A facile synthesis and biological applications of silver (DH-AgNps) gold nanoparticles (DH-AuNps) mediated by the aqueous extract Angelicae Pubescentis Radix (Du Huo) are explored. Du Huo is a medicinal root belonging to Angelica pubescens Maxim which possesses anti-inflammatory, analgesic, antioxidant properties. The absorption spectra in varying metal ion concentration, pH, reaction temperatures, time were recorded ultraviolet-visible (UV-Vis) spectroscopy. presence DH-AgNps DH-AuNps was...

10.1186/s11671-017-1833-2 article EN cc-by Nanoscale Research Letters 2017-01-17

Abstract: There has been a growing interest in the design of environmentally affable and biocompatible nanoparticles among scientists to find novel safe biomaterials. Panax ginseng Meyer berries have unique phytochemical profile exhibit beneficial pharmacological activities such as antihyperglycemic, antiobesity, antiaging, antioxidant properties. A comprehensive study biologically active compounds berry extract (GBE) ability (GB) material for biosynthesis gold (GBAuNPs) silver (GBAgNPs) was...

10.2147/ijn.s118373 article EN cc-by-nc International Journal of Nanomedicine 2017-02-01

Abstract: Pharmacologically active stem of the oriental herbal adaptogen, Siberian ginseng, was employed for ecofriendly synthesis ginseng silver nanoparticles (Sg-AgNPs) and gold (Sg-AuNPs). First, metabolic characterization sample, liquid chromatography-tandem mass spectrometry analysis (indicated presence eleutherosides A E), total phenol content, reducing sugar were analyzed. Second, water extract sample mediated biological both Sg-AgNPs Sg-AuNPs that crystalline face-centered cubical...

10.2147/ijn.s108549 article EN cc-by-nc International Journal of Nanomedicine 2016-07-01

The current study highlights the rapid biosynthesis of gold nanoparticles (Gu–AuNps) and silver chloride (Gu–AgClNps) by aqueous root extract Glycyrrhiza uralensis, a medicinal plant. G. uralensis has been reported for anticancer hepatoprotective effects. reduction chloroauric acid nitrate prompted formation Gu–AuNps Gu–AgClNps within 4 40 min at 80 °C, respectively. complete reaction did not require supplemental reducing stabilizing agents, which demonstrated green synthesis. Field emission...

10.1080/21691401.2017.1307213 article EN Artificial Cells Nanomedicine and Biotechnology 2017-04-04

The design of mild and non-toxic synthesis metallic nanoparticles is a topical subject in the nanotechnology field. objective this present study to screen bioactivity biosynthesized by aqueous fruit extract Chaenomeles sinensis. reducing stabilizing ability C. sinensis fabricate gold (Cs-AuNps) silver (Cs-AgNps) was confirmed UV–visible (UV–Vis) spectroscopy at 562 nm 477 nm, respectively. field-emission transmission electron microscopy (FE-TEM) X-ray diffraction analysis (XRD) verify...

10.1080/21691401.2017.1332636 article EN Artificial Cells Nanomedicine and Biotechnology 2017-06-06

Green synthesis of gold (CB-AuNps) and silver (CB-AgNps) nanoparticles using Cibotium barometz root extract was highlighted. CB-AuNps were synthesized almost instantly CB-AgNps formed after 25 min in a heated aqueous extract. The formation detected at 548 412 nm; they spherical with crystallite sizes 6 nm 23 nm, respectively. further investigated for their antimicrobial activity against Escherichia, Staphylococcus aureus, Salmonella enterica, Pseudomonas aeruginosa. Furthermore, scavenging...

10.1080/21691401.2016.1260580 article EN Artificial Cells Nanomedicine and Biotechnology 2016-12-04

Background: Zinc oxide nanoparticles (ZnO NPs) are used in modern cancer therapy based on their specific target, efficacy, low toxicity and biocompatibility.The photocatalytic performance of (ZnO) nanocomposites with hyaluronic acid (HA) was to study anticancer properties against various human cell lines.Methods: functionalized by were prepared a co-precipitation method (HA-ZnONcs).The submicron-flower-shaped further ginsenoside Rh2 cleavable ester bond via carbodiimide chemistry form...

10.2147/ijn.s221328 article EN cc-by-nc International Journal of Nanomedicine 2019-10-01

We report a non-covalent loading of ginsenoside compound K (CK) onto our previously reported gold nanoparticles (DCY51T-AuCKNps) through one-pot biosynthesis using probiotic Lactobacillus kimchicus DCY51T isolated from Korean kimchi. The ginsenoside-loaded were characterized by various analytical and spectroscopic techniques such as field emission transmission electron microscopy (FE-TEM), energy-dispersive X-ray (EDX) spectroscopy, elemental mapping, powder diffraction (XRD), selected area...

10.1080/21691401.2018.1541900 article EN cc-by Artificial Cells Nanomedicine and Biotechnology 2019-01-19

Ginsenoside F1 has been described to possess skin-whitening effects on humans. We aimed synthesize a new ginsenoside derivative from and investigate its cytotoxicity melanogenesis inhibitory activity in B16BL6 cells using recombinant glycosyltransferase enzyme. Glycosylation the advantage of synthesizing rare chemical compounds common with great ease.UDP-glycosyltransferase (BSGT1) gene Bacillus subtilis was selected for cloning. The enzyme purified, characterized, utilized enzymatically...

10.1016/j.jgr.2016.12.009 article EN cc-by-nc-nd Journal of Ginseng Research 2016-12-24

Abstract The thermal decomposition of dolomite at various constant temperatures and carbon dioxide pressures has been investigated by the ‘loss‐of‐weight method.’ Depending on these conditions, can be decomposed either stepwise to magnesium oxide calcium carbonate (‘half‐burnt dolomite’) with subsequent dissociation carbonate, or in a single stage both oxide. It is most significant that partial independent pressure occurring within same narrow temperature range, about 680°. If ambient...

10.1002/jctb.5010020603 article EN Journal of Applied Chemistry 1952-06-01

A rapid biological synthesis of multifunctional gold nanoparticle (AuNp) and monodisperse silver (AgNp) was achieved by an aqueous extract black Panax ginseng Meyer root. The physicochemical transformation into (BG) greatly enhanced the pharmacological activities white its minor ginsenoside content. optimal temperature conditions kinetics bioreduction were investigated. Formation BG-AuNps BG-AgNps verified ultraviolet-visible spectrophotometry at 548 412 nm, respectively. biosynthesized...

10.2147/ijn.s113692 article EN cc-by-nc International Journal of Nanomedicine 2016-12-01

Although hierarchical porous carbon materials have been widely used for electrocatalysis, the role of curvature in nanostructures during electrochemical reactions remains poorly understood due to a lack experimental models featuring clearly defined curved geometries and periodic structures. In this study, we fabricate cobalt- nitrogen-containing nanoplates with trimodal porosity (macro-, meso-, micropores) continuous, homogeneous edges (Co/N-CNP-CURV) using polystyrene-directed templating...

10.1021/acsnano.4c06404 article EN ACS Nano 2025-03-18

This research article investigates the one-pot synthesis of gold and silver chloride nanoparticles functionalized by fruit extract Crataegus pinnatifida as reducing stabilizing agents their possible roles novel anti-inflammatory agents. Hawthorn (C. pinnatifida) fruits are increasingly popular raw materials for functional foods potential because abundant flavonoids. The reduction auric nitrate aqueous led to formation nanoparticles. were further characterized field emission transmission...

10.1080/21691401.2017.1376674 article EN Artificial Cells Nanomedicine and Biotechnology 2017-09-18

Stevia rebaudiana leaves is a well-known medicinal plant for its non-caloric bio-sweetener. To enhance value addition, employed first time synthesis and stabilization of ZnO nanoparticles. The characterization using UV-Spec, FE-TEM, XRD, DLS revealed that SR-ZnO (ZnO particles obtained from S. rebaudiana) were flower-shape, 500–1,000 nm sizes, hydrodynamic diameter Z-average polydisperse was 582.35 ± 52.40 with PDI 0.33 0.002. Furthermore, 76% degradation methylene blue dye within 30 min...

10.1080/24701556.2019.1580291 article EN Inorganic and Nano-Metal Chemistry 2019-01-02

Background: Mountain ginseng (Panax Meyer), which belongs to Araliaceae family, grows naturally in the
 mountains of Korea. It is highly valued owing its enhanced pharmacology effects such as immunostimulating,
 antioxidant, anti-cancer and antiaging activity. An alternative accessing the sparse mountain therapy benefits is
 by tissue-cultured roots ginseng. The aim this study evaluate effect water extract cultured
 (CRMG) specifically major compound ginsenoside Re (Re)...

10.21010/ajtcam.v14i5.24 article EN African Journal of Traditional Complementary and Alternative Medicines 2017-10-01

Excessive inflammation can lead to chronic diseases, necessitating the development of effective anti-inflammatory therapies. This study investigates effects gold nanoparticles (AuNps) synthesized using Lactobacillus kimchicus DCY51T, a probiotic strain from Korean kimchi. The objective is explore potential DCY51T-AuNps in modulating inflammatory responses RAW264.7 macrophage cells. Methods: AuNps were through meticulous procedure involving DCY51T. isolation and subsequent cultivation cell...

10.15294/biosaintifika.v16i3.17103 article EN Biosaintifika Journal of Biology & Biology Education 2024-12-14
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