A5053506129- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Memory and Neural Mechanisms
- Retinal Development and Disorders
- Neural dynamics and brain function
- Alzheimer's disease research and treatments
- Neurological Disease Mechanisms and Treatments
- Psychedelics and Drug Studies
- Cholinesterase and Neurodegenerative Diseases
University of Copenhagen
2021-2023
Lundbeck (Denmark)
2021-2023
Quality of life is often reduced in patients with sleep-wake disorders. Insomnia commonly treated benzodiazepines, despite their well-known side effects. Pellotine (
Background: Tauopathies such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are characterized by formation of neurofibrillary tangles consisting hyperphosphorylated tau protein. Early pathophysiological functional changes related to considered occur prior extensive neurodegeneration. Hyperphosphorylated has been detected in postmortem retinas AD FTD patients, the visual pathway is an easily accessible system a clinical setting. Hence, assessment function may offer potential...
Tau protein pathology is a hallmark of many neurodegenerative diseases, including Alzheimer's Disease or frontotemporal dementia. Synaptic dysfunction and abnormal visual evoked potentials have been reported in murine models tauopathy, but little known about the state network activity on single neuronal level prior to brain atrophy. In present study, oscillatory rhythms single-cell calcium primary cortex pyramidal neuron population were investigated basal light states rTg4510 tauopathy mouse...
Abstract Tauopathies such as Alzheimer’s Disease (AD) and frontotemporal dementia (FTD) are characterized by formation of neurofibrillary tangles consisting hyperphosphorylated tau protein. Early pathophysiological functional changes related to considered occur prior extensive neurodegeneration. Hyperphosphorylated has been detected in postmortem retinas AD FTD patients, the visual pathway is an easily accessible system a clinical setting. Hence, assessment function may offer potential...
Abstract Tau protein pathology is a hallmark of many neurodegenerative diseases, including Alzheimer’s Disease or frontotemporal dementia. Synaptic dysfunction and abnormal visual evoked potentials have been reported in murine models tauopathy, but little known about the state network activity on single neuronal level prior to brain atrophy. In present study, oscillatory rhythms single-cell calcium primary cortex pyramidal neuron population were investigated basal light states rTg4510...