A5063760422- Renal cell carcinoma treatment
- Renal and related cancers
- Cancer, Lipids, and Metabolism
- Biomarkers in Disease Mechanisms
- Dietary Effects on Health
- Nanoplatforms for cancer theranostics
- Cancer Genomics and Diagnostics
- Endometriosis Research and Treatment
- Probiotics and Fermented Foods
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- Lung Cancer Treatments and Mutations
- Cancer-related molecular mechanisms research
- Apelin-related biomedical research
- Nanoparticle-Based Drug Delivery
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Genetic Associations and Epidemiology
- Nutrition, Genetics, and Disease
- HER2/EGFR in Cancer Research
- Cancer Risks and Factors
- Lung Cancer Research Studies
- Gut microbiota and health
- Advanced Chemical Sensor Technologies
- Adipokines, Inflammation, and Metabolic Diseases
Subang Jaya Medical Centre
2024
Hospital Universiti Sains Malaysia
2021
Universiti Sains Malaysia
2021
University of Malaya
2018-2020
Nanoparticles have tremendous therapeutic potential in the treatment of cancer as they increase drug delivery, attenuate toxicity, and protect drugs from rapid clearance. Since Doxil®, first FDA-approved nanomedicine, several other nanomedicines been approved successfully increased efficacy over their free counterparts. Although mechanisms action are well established, effects towards our immune system, particularly tumor microenvironment (TME), still warrant further investigation. Herein, we...
The mechanisms that link obesity and cancer development are not well-defined. Investigation of leptin receptor expressions may help define some the mechanisms. These proteins known for associating with immune response, angiogenesis and, signalling pathways such as JAK2/STAT3, PI3K, AKT pathways. Tissue can be easily detected immunohistochemistry (IHC), a technique widely used both in diagnostic research laboratories. identification altered levels tumour tissues lead to targeted treatment...
Recent years have witnessed an unprecedented growth in the research area of nanomedicine. There is increasing optimism that nanotechnology applied to medicine will bring significant advances diagnosis and treatment various diseases, including colorectal cancer (CRC), a type neoplasm affecting cells colon or rectum. findings suggest role microbiota crucial development CRC its progression. Dysbiosis condition disturbs normal microbial environment gut often observed patients. In order detect...
Human epidermal growth factor receptor 2 (HER2) is known for its oncogenic activities in diverse cancers, including non-small cell lung cancer (NSCLC). However, the prevalence of
The evolution of therapy for advanced or metastatic renal cell carcinoma (RCC) progressed over the past decade from using cytokine immunotherapy to targeted which predominantly inhibits angiogenesis via vascular endothelial growth factor (VEGF) and mammalian target rapamycin (mTOR) pathways. Currently, there are several approved agents in first-line (e.g. sunitinib, pazopanib, ipilimumab/nivolumab, bevacizumab/IFN-α combination temsirolimus) second-line settings everolimus, axitinib,...