A5023375685- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Heart Failure Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Chromatin Remodeling and Cancer
- Streptococcal Infections and Treatments
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Radiology practices and education
- Aortic Disease and Treatment Approaches
- Neuroblastoma Research and Treatments
- COVID-19 Clinical Research Studies
- Global Health and Epidemiology
- Anatomy and Medical Technology
- Heme Oxygenase-1 and Carbon Monoxide
- Respiratory Support and Mechanisms
- Protein Degradation and Inhibitors
- Nosocomial Infections in ICU
- Chronic Disease Management Strategies
Alice Ho Miu Ling Nethersole Hospital
2021-2024
University of Tasmania
2023
Chinese University of Hong Kong
2016-2022
Prince of Wales Hospital
2014-2021
Background: There is a lack of consensus on the timing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) liberation. VA-ECMO weaning usually consists serial decrements until an idling flow achieved, supported by echocardiographic and haemodynamic assessments. Even with minimal flow, right ventricular (RV) preload reduced and, hence, heart function not fully tested under adequate loading conditions. Following use novel technique called Pump Controlled Retrograde Trial Off (PCRTO) in...
Abstract Background Globally, mortality rates of patients admitted to the intensive care unit (ICU) have decreased over last two decades. However, evaluations temporal trends in characteristics and outcomes ICU Asia are limited. The objective this study was describe risk adjusted all publicly funded ICUs Hong Kong a 11-year period. secondary validate predictive performance Acute Physiology And Chronic Health Evaluation (APACHE) IV for Kong. Methods This an population-based retrospective...
Outcomes of patients receiving extracorporeal membrane oxygenation (ECMO) therapies risk-adjusted by ECMO specific scores have rarely been reported. Our primary aim was to determine the risk adjusted outcome these use Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP), After Veno-Arterial-ECMO (SAVE) and APACHE II scores. The differences in predicted mortality between scoring systems were analyzed.This is a single-center retrospective study reviewing 62 who received...
Key Clinical Message Extracorporeal membrane oxygenation ( ECMO )‐related hemolysis is a rare but devastating condition. Death inevitable without early recognition and prompt management. Endogenous carbon monoxide production, as an epiphenomenon of hemolysis, potentially allows rapid detection such condition by use point‐of‐care CO ‐oximetry carboxyhemoglobin.
Direct comparisons between COVID-19 and influenza A in the critical care setting are limited. The objective of this study was to compare their outcomes identify risk factors for hospital mortality.This a territory-wide, retrospective on all adult (≥18 years old) patients admitted public intensive units Hong Kong. We compared 27 January 2020 26 2021 with propensity-matched historical cohort 2015 2020. reported mortality time death or discharge. Multivariate analysis using Poisson regression...
Abstract Background Necrotizing fasciitis (NF) is a rare but potentially life-threatening soft tissue infection. The objective of this study was to assess the association between timely surgery within 6 h and hospital mortality in patients with limb NF, describe trends time standardized ratio (SMR) over 11 years. Methods This multicenter, retrospective cohort all intensive care unit who had emergency 24 hospitalization for NF April 1, 2008 March 31, 2019 Hong Kong. Timely defined as first...
The utilization of extracorporeal membrane oxygenation (ECMO) has increased rapidly around the world. Being an overall low-volume high-cost form therapy, effectiveness having care delivered in segregated units across a geographical locality is debatable.All adult cases admitted to public hospitals Hong Kong between 2010 and 2019 were included. "High-volume" centers defined as those with >20 respective calendar year, while "low-volume" ≤20. Clinical outcomes patients who received high-volume...
Air in circuit patients receiving extracorporeal membrane oxygenation (ECMO) is an emergency. Different protocols have been suggested to deal with this rare but fatal complication, their efficacies are rarely reported. We report our institutions' experience the management of air Cardiohelp HLS ECMO system. Between October 2009 and July 2020, 4 out 116 developed gas bubbles or systemic embolism. The clinical characteristics these patients, source air, presence arterial pump airlock,...
Abstract Background To compare the outcomes of patients requiring extracorporeal membrane oxygenation (ECMO) support who had a restrictive transfusion strategy with those liberal strategy. Study Design and Methods We retrospectively reviewed all adult from 2010 to 2019 received minimum one packed red blood cell (pRBC) during ECMO. Hemoglobin values before each were retrieved. Restrictive was defined as threshold ≤8.5 g/dl in episodes for single patient, while >8.5 any episode. Results The...
Tuberculosis (TB) is a preventable and curable disease, but mortality remains high among those who develop sepsis critical illness from TB.This was population-based, multicentre retrospective cohort study of patients admitted to all 15 publicly funded Hong Kong adult intensive care units (ICUs) between 1 April 2008 31 March 2019. 940 critically ill with at least one positive Mycobacterium tuberculosis (MTB) culture were identified out 133 858 ICU admissions. Generalised linear modelling used...
The incidence of lower limb ischaemia ranges from 11%–52% in patients receiving VA ECMO. reported rate amputation 2%–10%. Patients with vascular complications related to carries a higher risk death. Antegrade perfusion superficial femoral artery via distal catheter (DPC) has been shown be an effective therapy reduce the ischaemia. However, clinical indications remain largely unclear various strategies. While benefits unknown, there is increasing experience on use near-infrared reflectance...