Thailand has vast areas of tropical forests with many indigenous plants, but limited information is available on their phytochemical profile and in vitro inhibitions enzymatic nonenzymatic reactions. This study investigated phenolic profiles using liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS), antioxidant activities, inhibitory activities 10 plants key enzymes related to obesity (lipase), diabetes (α-amylase α-glucosidase), Alzheimer's disease...

Sacred lotus (Nelumbo nucifera) has long been used as a food source and ingredient for traditional herbal remedies. Plant parts contain neuroprotective agents that interact with specific targets to inhibit Alzheimer’s disease (AD). Organic solvents including methanol, ethyl acetate, hexane, n-butanol, are widely employed extraction of sacred but impact safety. Seed embryo, flower stalk, stamen, old leaf, petal, leaf stalk were extracted using hot water (aqueous extraction). The extractions...

Legumes and pulses are nutrient-dense foods providing a good source of protein, complex carbohydrates, fiber, vitamins, minerals, bioactive compounds. To breed new lineage beans with specific nutritional health beneficial purposes, more information on original must be obtained. However, data concerning the nutritive compositions, total phenolic contents (TPCs), benefits regarding antioxidant potentials some in Thailand remain scarce, causing difficulty decisional selection to lineage. Thus,...

Objective: The rise in non-communicable diseases (NCDs); such as cardiovascular diseases, hypertension, diabetes, and cancers, Bhutan is linked to unhealthy diets that are high salt saturated fats. This study aimed reformulate popular high-sodium Bhutanese cheese curries—Shakam Datshi Kewa Datshi—by reducing their sodium content using potassium chloride (KCl) monosodium glutamate (MSG), while preserving traditional flavors improving nutritional profiles.Material Methods: Shakam were...

Rice (Oryza sativa) is a staple food crop with significant role in nutrition and health. Its production yield mainly depends on climatic conditions. Soil salinity, an abiotic factor as resulting from drought, also impacts rice growth, production, quality. Researchers have widely investigated newly developed salt-tolerant varieties suitable fertilizers to enhance However, the effects of planting times in- season off-season grown soils varying salinity levels qualities, such nutrients,...

In the present study, response surface methodology (RSM) and Box-Behnken design (BBD) were employed to optimize conditions for extraction of C. maxima albedo from agricultural waste, obtain notable phytochemicals. Ethanol concentration, temperature, time included as key factors contributing extraction. The results showed that optimum condition was 50% (v/v) aqueous ethanol at 30 °C 4 h, which provided total phenolic contents flavonoid 15.79 mg gallic equivalent/g dry weight (DW) 4.50...

A previous study reported that the ethanolic extract of edible fern, Diplazium esculentum (Retz.) Sw. (DE), obtained from a non-optimized extraction condition exhibited anti-Alzheimer’s disease (AD) properties through inhibition rate-limiting enzyme in amyloid peptide formation, β-secretase-1 (BACE-1). Nevertheless, or suboptimal may lead to several issues, such as reduction efficiency and increased time plant materials. In this study, DE was optimized obtain appropriate BACE-1 using...

Sacred lotus (Nelumbo nucifera) is a commercial product in Asian countries. Almost all parts of the plant are consumed as food or used traditional medicine due to their high contents secondary metabolites such phenolics and alkaloids. However, agricultural management sacred occurs during rainy season, enters resting stage dry season. Thus, seasonal variation (beginning, middle end season) was investigated for total phenolic (TPCs), antioxidant capacities inhibitions key enzymes relevant...

Rice (Oryza sativa) is a staple food crop for over half of the world’s population. However, drought as result climate change has led to increased soil salinity, thereby reducing agricultural potential, especially rice nutritional compositions and biochemical properties. Nevertheless, management by using suitable fertilizers might be able improve quality even though these samples were grown in with high degree salinity. This study investigated compositions, phenolic contents, antioxidant...

Aeginetia indica L., a parasitic root in the Orobanchaceae family, is used as food colorant traditional Thai desserts. However, scant information available on its applications well medicinal properties, while overharvesting by local people has severely depleted wild plant populations. This research, thus, aimed to extract optimized total phenolic content (TPC) varying extraction conditions using response surface methodology (RSM) and Box–Behnken design (BBD). Results indicated that an...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. To fight the disease, natural products, including mulberry, with antioxidant activities and inhibitory against key enzymes (acetylcholinesterase (AChE), butyrylcholinesterase (BChE), beta-secretase 1 (BACE-1)) are of interest. However, even in same cultivars, mulberry trees grown different populated locations might possess disparate amounts phytochemical profiles, leading to dissimilar health properties, which cause...

Legumes and pulses are important food components with various phytochemicals health benefits. However, the health-related bioactivities of some underutilized species remain uninvestigated. To breed a new bean lineage particular properties, this study investigated phenolics (specifically, isoflavones) in vitro inhibitory activities enzyme relevant to non-communicable diseases cultivars Phaseolus lunatus (lima beans), compared commonly consumed P. vulgaris (red kidney bean) beans Glycine Vigna...

Hodgsonia heteroclita subsp. Indochinensis W.J.de Wlide & Duyfjes (or Making in Thai) is a neglected and underutilized crop (NUC) with high fat containing nuts. In this study, the enzyme-assisted mechanical extraction of H. seed oil was investigated using response surface methodology (RSM) to predict optimal conditions. The most efficient enzyme used experiment mixture Flavourzyme® Viscozyme® (1:1, w/w). predicted maximum yield 46.44%, following conditions: 2.98% (w/w) loading, 48 °C...

Nephelium hypoleucum Kurz is an evergreen tree in the Sapindaceae family, mostly found forests of some Southeast Asia countries, especially Thailand. The lack biological information regarding this has led to inappropriate agricultural management, conservation and utilization. Thus, study aims examine nutritional composition, organic acid phenolic profiles vitro health properties through several key enzyme inhibitions against civilization diseases including Alzheimer’s disease (β-secretase...

The cold brew coffee (CBC) trend is increasing globally; nevertheless, there limited literature on this popular beverage. Many studies have focused the health benefits of green beans and brewed by conventional hot water methods. Thus, whether conveys similar still unclear. This study aimed to investigate influences brewing conditions physicochemical properties using response surface methodology in order optimize parameters compare resulting CBC with from French Press method. Central...

Plant phenolics have been known for various biological activities. This study aims to extract and examine the presence of in Bao mango (Mangifera indica L. var.) peel ethanolic (MPE). Further, antioxidant, anti-diabetic (α-amylase, α-glucosidase inhibitory activity), anti- Alzheimer's disease (AD) (acetylcholinesterase (AChE), butyrylcholinesterase (BChE), β-secretase (BACE-1) activity) efficacy MPE were determined. The results indicated that mangiferin (8755.89 mg/ 100 g extract) was major...

Cyanobacteria, especially Arthrospira, are valuable resources of nutrients and natural pigments with many beneficial health-related properties. This study optimized the extraction conditions Arthrospira to achieve high phenolic contents antioxidant activities. Under conditions, bioactive compounds (phenolics pigment components), activities, inhibitions key enzymes relevant some non-communicable diseases were compared between platensis maxima. Optimized determined as 2 h shaking time, 50 °C...

Undernutrition and mineral deficiencies negatively impact both the health academic performance of school children, while diets high in phytic acid some phenolics inhibit absorption minerals such as iron zinc. This study developed instant porridge powders rich zinc using pregelatinized chickpea flour (PCPF) foxtail millet (PFMF) assessed potential utilizing roselle calyx powder (RCP) a source organic acids to enhance its bioaccessibility. Physical properties, nutrients, inhibitors vitro...

Most biowaste produced by domestic food preparation and processing has no value, is difficult to manage, detrimental the environment. Oil extraction from Hodgsonia heteroclita seeds produces large amounts of oilseed cake powder (OCP) as biowaste. The residual phytochemicals using simple eco-friendly methods can increase economic utility OCP. This study optimized process for OCP a Box–Behnken design response surface methodology. condition was 30 °C 5 h in 50% (v/v) ethanol, giving total...

Adenia viridiflora Craib. is an indigenous plant found in Thailand, Cambodia and Vietnam that has become threatened owing to lack of knowledge about its agricultural management. This now rare the wild was registered Plant Genetic Conservation Project under initiation Her Royal Highness Princess Maha Chakri Sirindhorn (RSPG) promote sustainable conservation optimally beneficial utilization. A. a long history utilization as nutrient-rich source with medicinal properties but scientific evidence...

The physicochemical and functional properties, structures, nutritional characterizations of Hodgsonia heteroclita oilseed cake powder (OCP) obtained from oil extraction with no pretreatment (NP), heat (HP; drying at 55 °C until reaching 10% moisture content), the combined enzymatic (HEP; 2.98% (w/w) enzyme loading, 48 incubation temperature 76 min time) were investigated. HP HEP caused a decrease in lightness but an increase yellow–brown color OCP. results showed that HEP-OCP had...

Traditional remedies using natural ingredients have been handed down over generations, providing collective information for the development of modern therapeutics. These products a long history safe consumption with curative effects but lack scientific-based evidence hinders mass production new containing active particular medicinal properties. This research investigated phenolic profiles and biochemical properties 29 herbal identified in two traditional Thai remedies, Prasachandaeng (PSCD)...

In this study, a high-temperature-tolerant strain of the king oyster mushroom (Pleurotus eryngii) was generated by chemical mutagenesis. Cultivation P. eryngii generally involves incubating mycelia at 25°C and then moving spawns for further incubation 18°C fruitification. However, in tropical countries, temperature is major concern production where average 32°C. current were treated with ethyl methane sulphonate (EMS) or methyl (MMS) chemical-induced mutation. Seven mutants (EMS 1, 2, 6, 26,...