A5033930205- Drug-Induced Adverse Reactions
- Asthma and respiratory diseases
- Acne and Rosacea Treatments and Effects
- Urticaria and Related Conditions
- Obesity, Physical Activity, Diet
- Botulinum Toxin and Related Neurological Disorders
- Ocular Surface and Contact Lens
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Diet and metabolism studies
- Ophthalmology and Eye Disorders
- Stoma care and complications
- Glaucoma and retinal disorders
- Immunodeficiency and Autoimmune Disorders
- Respiratory and Cough-Related Research
- Pharmaceutical studies and practices
- Parkinson's Disease Mechanisms and Treatments
- Pharmacovigilance and Adverse Drug Reactions
- Myasthenia Gravis and Thymoma
- Pain Mechanisms and Treatments
- Economic and Financial Impacts of Cancer
- Cancer survivorship and care
- Monoclonal and Polyclonal Antibodies Research
- Lymphoma Diagnosis and Treatment
- Corneal Surgery and Treatments
Chulalongkorn University
2018-2025
Nationwide Children's Hospital
2023
Agencia de Evaluación de Tecnologías Sanitarias
2022
Instituto Nacional de Salud
2022
Sistema Nacional de Salud
2022
University of Arizona
2007-2015
Abstract Inulin might improve body composition in obese children. We aimed to determine the effects of inulin supplementation on and metabolic outcomes A randomized, double-blinded placebo-controlled study was conducted Thai children aged 7–15 years. Participants were assigned 3 treatment groups for 6 months: 13 g extracted powder from Jerusalem artichoke, isocaloric maltodextrin, dietary fiber advice groups. Body assessed by bioelectrical impedance analysis. One-hundred fifty-five completed...
Managing obesity in children remains challenging. In addition to body mass index (BMI), incorporating composition into evaluations of post-obesity interventions would help assess changes adiposity. This study aimed identify the relationship between dietary intake, physical activity, and BMI z-scores adiposity among with obesity. Children aged 7-15 years received monthly activity instructions for 6 months. Three-day records questionnaires were collected at 0, 3, Body was measured using...
Types of surgery for rectal cancer (RC), including permanent ostomy (PO) or temporary followed by anastomosis (TO) initial (AN), can affect psychological and financial well-being during active treatment. However, these relationships have not been well studied among long-term survivors (≥5 years post-diagnosis).A mailed survey with 576 RC who were members Kaiser Permanente was conducted in 2010-2011. Prevalence current depression ascertained using a score ≤45.6 on the Short Form-12 version 2...
Purpose: To explore whether there was a significant relationship between difficulty paying for ostomy supplies and overall quality of life among sample ostomates receiving care from the Veterans Health Administration (VHA). Methods: The data were collected as part Affairs (VA) Ostomy Health-Related Quality Life Study, in which 511 respondents (239 cases, 272 controls) completed survey instrument that included modified City Hope (mCOH-QOL) questionnaire, SF-36V, sociodemographic items....
Acne vulgaris (AV) exacerbation after whey protein (WP) consumption remains inconclusive among experts.
We aimed to construct predictive models for the overall survival (OS), progression-free (PFS), and distant metastasis-free (DMFS) nasopharyngeal carcinoma (NPC) patients by using CT-based radiomics.We collected data from 197 NPC patients. For each patient, radiomic features were extracted CT image acquired at pretreatment via PyRadiomics. Feature selection was performed in two steps. First, with high inter-observer variability based on multiple tumor delineations excluded. Then, stratified...
Change in cognitive function is increasingly being recognized as an adverse outcome related to chemotherapy treatment. These changes need not be severe impact patient functional ability and quality of life. The primary goal this study was determine if there evidence the domains attention, processing speed, response time among women with newly diagnosed advanced ovarian cancer who receive chemotherapy. Eligible patients were stage III-IV epithelial or peritoneal had yet received but...
Acne vulgaris is a common and chronic disease that impacts on physical psychological perceptions. Cosmeceutical products are widely used as adjunct therapy to standard treatments.To evaluate the efficacy of cosmeceutical comprising glycolic acid, salicylic gluconolactone, licochalcone A adapalene in mild-to-moderate acne vulgaris.A 28-day, double-blind, within-person comparative study was conducted with total 25 subjects. Each participant received two products, consisting (1) product mixed...
Abstract Background At present, no predictive models are available to determine the probability of in‐hospital mortality rates (HMRs) in all phenotypes severe cutaneous adverse reactions (SCARs). Objectives Our study explored whether simple clinical and laboratory assessments could help predict HMRs any SCAR patients. Methods Factors influencing 195 adults diagnosed with different were identified, their optimal cut‐offs determined by Youden's index. Predictive equations for patients...
Background: Obesity is associated with dysbiosis, contributing to inflammation and insulin resistance. Inulin might reduce by manipulating intestinal microbiota. Objective: We aimed determine the effects of inulin supplementation on assess relationships inflammatory cytokines adiposity resistance in obese Thai children. Design: Obese children ages 7–15 years were randomly assigned (intervention), maltodextrin (placebo), dietary fiber advice groups. All participants received monthly follow-up...
Purpose: To identify ophthalmic findings in Alzheimer's type dementia (ATD) compared to normal subjects.Patients and Methods: This comparative descriptive study included participants from the institution's cognitive fitness center.Complete examinations were performed.Optical coherence tomography (OCT) OCT angiography (OCTA) used analyze retinal thickness vascular density.The Ocular Surface Disease Index (OSDI) score tear breakup time (TBUT) assess dry eye.The blink rate was counted by a...
To adapted the Drug Hypersensitivity Quality of Life (DrHy-Q) Questionnaire from Italian into Thai and assessed its validity reliability.Prospectively recruited during January 2012-May 2017.Multicenter; six tertiary university hospitals.Total 306 patients with physician-diagnosed drug hypersensitivity.Internal consistency test-retest reliability were evaluated among 68 participants using Cronbach's ɑ intra-class correlation coefficient (ICC). The DrHy-Q was who completed World Health...
Nowadays, preoperative radio-chemotherapy is a standard treatment for locally advanced esophageal squamous cell carcinoma (ESCC). Tumor regression grade (TRG), referring to classification of cancer response treatment, can predict prognosis survival. Many TRG systems are proposed use in cancer, but none them has become grading system. This research compared five systems, including Mandard system, Chirieac Schneider Hermann and Japan Esophageal Society (JES) find the most accurately predictive...
Abstract In a double‐blind, randomized controlled trial, we investigated the effectiveness of adding antiplatelet drugs to up‐dosing antihistamines for treatment chronic spontaneous urticaria (CSU) in patients with elevated D‐dimer levels who had an inadequate response conventional antihistamine doses. Twenty Urticaria Activity Score over 7 days (UAS7) ≥16 and >500 ng/mL were receive either therapy (cilostazol 150 mg/day + dipyridamole 50 mg/day) (desloratadine 20 or alone 4 weeks. The...
The purpose of this study was to investigate panels enzyme-linked immunospot assays (ELISpot) detect drug-specific mediator releasing cells for confirming culprit drugs in severe cutaneous adverse reactions (SCARs).Frequencies drug-induced interleukin-22 (IL-22)-, interferon-gamma (IFN-γ)-, and granzyme-B (GrB)-releasing were measured by incubating peripheral blood mononuclear (PBMCs) from SCAR patients with the drugs. Potential immunoadjuvants supplemented enhance responses.Twenty-seven...
Post-acne erythema (PAE) is one of the most common sequelae acne inflammation. Unfortunately, treatment PAE remains challenging due to limited effective topical treatments. The objectives this study were evaluate efficacy and safety oxymetazoline hydrochloride (OxH) 0.05% solution for PAE. This was a split-face, participants-and investigators-blinded, randomized, placebo-controlled trial conducted between December 2021 March 2022 in Bangkok, Thailand. Healthy adults aged from 18 45 years...
To compare Thais' health-related quality of life (HRQOL) and severity grading, efficacy safety in daily-life-affected benign essential blepharospasm (BEB) patients at baseline after Botulinum toxin type A (BTX-A) treatment.Prospective-observational study.BEB with Jankovic rating scale (JRS) least 3 both frequency graded from 14 institutes nationwide were included August 2020 to June 2021.Demographic data, HRQOL evaluated by the Thai version EQ-5D-5L NEI-VFQ-25 questionnaires, grading score...
Obesity is a major threat to public health. Eating behavior and dietary intake of especially high energy-dense food with low nutrients contribute the current epidemic childhood obesity. However, relationship between eating body composition has yet be examined in Thai children adolescents We assessed association children's behaviors their prerandomized patients who participated randomized trial titled "Impact Dietary Fiber as Prebiotics on Intestinal Microbiota Obese Children". During...
Abstract This study evaluated human papillomavirus’s (HPV) role in pterygium pathogenesis, its autoinoculation from genitalia to ocular surface, potential cytokines involved, and crosstalk between dry eye (DE). cross-sectional enrolled 25 healthy controls (HCs) 116 patients. Four subgroups of DE were used cytokine evaluations. Conjunctival swabs first-void urine samples (i.e., samples) collected for HPV DNA detection using real-time polymerase chain reaction. Tear interleukin (IL)-6, IL-18,...
Abstract Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reactions with high mortality rates. Its sequelae, such as blindness, persist even after recovery. Patients SJS/TEN should be accurately diagnosed receive appropriate treatment soon possible. Therefore, identifying the factors for severity prediction is necessary. We aimed to clarify clinical parameters biological markers that can predict acute ocular complications (SOCs) in...
Low bone density (BD) has been reported in patients with hyperthyroidism. Whether or not levothyroxine (LT4) therapy children congenital hypothyroidism (CH) affects BD is unclear. Medical records of 45 various etiologies CH who had at least one measurement (32 female, mean age 7.6 +/- 2.6 years) were reviewed. The LT4 dose was 3.6 0.88 microg/kg/day. Cancellous (CaBD) measured by quantitative computed tomography (CT) all and 20 measurements cortical (CoBD), cross-sectional area (CSA) (CBA)...
The emergence of bacterial resistance is a global crisis. Prolonged use antibiotics especially in acne one issue concern among dermatologists. Ketoconazole (KTZ) cream, topical antifungal with anti-inflammatory and antiandrogenic actions, can decrease lipase activity Cutibacterium acnes vitro. We evaluated the efficacy safety KTZ cream mild adult female (AFA) by conducting randomized, double-blind, placebo-controlled trial using 2% placebo twice daily for 10 weeks. assessed improvement...