A5026750788- Inflammatory Bowel Disease
- Stoma care and complications
- Microscopic Colitis
- Colorectal Cancer Surgical Treatments
- Rheumatoid Arthritis Research and Therapies
- Colorectal Cancer Screening and Detection
- Nutrition and Health in Aging
- Systemic Lupus Erythematosus Research
- Cancer survivorship and care
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Palliative Care and End-of-Life Issues
- Pregnancy and Medication Impact
- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Gastric Cancer Management and Outcomes
- Bariatric Surgery and Outcomes
- Eosinophilic Esophagitis
- Glaucoma and retinal disorders
- Liver Diseases and Immunity
- Corneal surgery and disorders
- BRCA gene mutations in cancer
- Effects and risks of endocrine disrupting chemicals
- Psoriasis: Treatment and Pathogenesis
Kaiser Permanente
2015-2024
Colorado Permanente Medical Group
2003-2021
Kaiser Permanente Oakland Medical Center
2019-2021
Kaiser Permanente San Rafael Medical Center
2020
University of Washington
1992-2019
Seattle Children's Hospital
1996-2019
University of California, San Francisco
2007-2019
Johns Hopkins University
2019
Ibis Reproductive Health
2019
Molecular Templates (United States)
2018
Although tumor necrosis factor (TNF)-α antagonists are increasingly used in place of nonbiologic comparator medications, their safety profile remains incomplete.To determine whether initiation TNF-α compared with comparators is associated an increased risk serious infections requiring hospitalization.Within a US multi-institutional collaboration, we assembled retrospective cohorts (1998-2007) patients rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and psoriasis, psoriatic...
Animal studies have suggested that bisphenol-A (BPA) is a potential human endocrine disrupter; but evidence from needed. We conducted an occupational cohort study to examine the effect of exposure BPA on risk male sexual dysfunction. Current workers BPA-exposed and control factories were recruited. The exposed very high levels in their workplace. Male function was ascertained through in-person interviews using standard inventory. had consistently higher dysfunction across all domains than...
Herpes zoster reactivation disproportionately affects patients with rheumatoid arthritis (RA). It is unclear whether anti-tumor necrosis factor (anti-TNF) therapy elevates herpes risk.To ascertain initiation of anti-TNF compared nonbiologic comparators associated increased risk.We identified new users among cohorts RA, inflammatory bowel disease, and psoriasis, psoriatic arthritis, or ankylosing spondylitis from 1998 through 2007 within a large US multi-institutional collaboration combining...
We investigated the efficacy of contralateral prophylactic mastectomy (CPM) in reducing breast cancer incidence and mortality among women who have already been diagnosed with cancer.This retrospective cohort study comprised approximately 50,000 were unilateral during 1979 to 1999. Using computerized data confirmed by chart review, we identified 1,072 (1.9%) had CPM. obtained covariate information for these a sample 317 did not undergo CPM.The median time from initial diagnosis end follow-up...
Purpose Intestinal stomas can pose significant challenges for long-term (≥ 5 years) rectal cancer (RC) survivors. Specifying common and sociodemographic or clinical differences will further the development of tailored interventions to improve health-related quality life (HRQOL). Patients Methods This was a matched cross-sectional study RC survivors conducted in three Kaiser Permanente regions. The mailed questionnaire included modified City Hope Quality Life-Ostomy (mCOH-QOL-Ostomy) Medical...
The objective of this study was to assess inflammatory bowel disease (IBD) medications in relation lymphoma risk.Information on IBD and relevant other utilization obtained from the Kaiser Permanente Registry, 1996-2009. Lymphoma cases were ascertained Cancer Registry. incidence compared between cohort general population.Of 16,023 patients without human immunodeficiency virus followed an average 5.8 years, 43 developed lymphoma. with did not differ respect past IBD-related visits, procedures,...
Outpatients with cancer receive complicated medication regimens in the clinic and home. Medication errors this setting are not well described. We aimed to determine rates types of systems factors associated error outpatients cancer.We retrospectively reviewed records from visits three adult one pediatric oncology Southeast, Southwest, Northeast, Northwest for using established methods. Two physicians independently judged whether an occurred (kappa = 0.65), identified its severity 0.76),...
We studied breast cancer incidence during the period 1973–1986 in Asian residents of three U.S. geographic areas. The rate Asian-American women born China or Japan and their U.S.-born counterparts was about 50% 75% that whites, respectively, approximately twice residing Asia. Breast nearly identical U.S.- foreign-born Filipino-Americans, but it 40% whites.
To evaluate post-cataract-surgery endophthalmitis rates in relation to changing practice patterns antibiotic administration.Kaiser Permanente, Diablo Service Area, California.Ecological time-trend study.During 2007 through 2011, 3 time periods were identified based on increasing adoption of intracameral injections after phacoemulsification cataract surgery. In 2007, patients primarily received postoperative drops without injection. During 2008 and 2009, addition the surgeons' usual topical...
There are few estimates of the incidence and prevalence inflammatory bowel disease in North American communities. We sought to estimate (IBD), including Crohn's (CD), ulcerative colitis (UC), among 3.2 million members Kaiser Permanente, Northern California, for period 1996-2002.All health plan who had one or more diagnoses CD (ICD-9 code 555) UC 556) on computerized records during 1996-2002 with at least 12 months membership were identified as possible IBD cases (N = 12,059). randomly...
Objective Estimates of the incidence and prevalence systemic lupus erythematosus (SLE) in US have varied widely. The purpose this study was to conduct California Lupus Surveillance Project (CLSP) determine credible estimates SLE prevalence, with a special focus on Hispanics Asians. Methods CLSP, which is funded by Centers for Disease Control Prevention, population‐based registry individuals residing San Francisco County, CA, from January 1, 2007 through December 31, 2009. Data sources...
Purpose/Objectives: To describe how gender shapes the concerns and adaptations of long-term (i.e., more than five years) colorectal cancer survivors with ostomies.
OBJECTIVE Some patients with colorectal cancer (CRC) require a permanent ostomy, which changes bodily function and can create psychosocial distress. However, little is known about the influence of men's support on women's adjustment to having an ostomy as result CRC. METHODS Participants initially completed City Hope-CRC Quality Life questionnaire. We then conducted in-depth interviews 30 female participants. Interview questions focused body image, gender, sexuality. Interviews were recorded...
To compare the incidence of cancer following tumor necrosis factor α (TNFα) inhibitor therapy to that with commonly used alternative therapies across multiple immune-mediated diseases.The Safety Assessment Biological Therapeutics study data from 4 sources: national Medicaid and Medicare databases, Tennessee Medicaid, pharmacy benefits plans for beneficiaries in New Jersey Pennsylvania, Kaiser Permanente Northern California. Propensity score-adjusted hazard ratios (HRs) 95% confidence...
<h3>Objectives</h3> To determine among patients with autoimmune diseases in the USA whether risk of non-viral opportunistic infections (OI) was increased new users tumour necrosis factor α inhibitors (TNFI), when compared to non-biological agents used for active disease. <h3>Methods</h3> We identified TNFI cohorts rheumatoid arthritis (RA), inflammatory bowel disease and psoriasis-psoriatic arthritis-ankylosing spondylitis during 1998–2007 using combined data from Kaiser Permanente Northern...