A5037142976- Iron Metabolism and Disorders
- Folate and B Vitamins Research
- Child Nutrition and Water Access
- Pregnancy and preeclampsia studies
- Hemoglobinopathies and Related Disorders
- Birth, Development, and Health
- Child Nutrition and Feeding Issues
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Breastfeeding Practices and Influences
- Prenatal Substance Exposure Effects
- Muscle Physiology and Disorders
- Obesity, Physical Activity, Diet
- Digestive system and related health
- Global Public Health Policies and Epidemiology
- Infant Nutrition and Health
- Food Security and Health in Diverse Populations
- Erythropoietin and Anemia Treatment
- Fluoride Effects and Removal
- Thyroid Disorders and Treatments
- Trace Elements in Health
- Gestational Diabetes Research and Management
- Body Composition Measurement Techniques
St.John's Medical College Hospital
2020-2025
St. John's National Academy of Health Sciences
2014-2023
St. John's University
2020-2022
St. John's School
2019
Women of reproductive age (WRA) are a high-risk population for anemia and micronutrient deficiencies. However, there few representative population-level data from India, which could help inform evidence-based recommendations policy.
In lower-middle-income settings, growth faltering in the first 6 mo of life occurs despite exclusive breastfeeding.The aim was to test efficacy an approach improve dietary adequacy mothers during lactation and thus their infants.Eligible mother-infant dyads (infants ≤7 d age) were randomly assigned either intervention or control groups. Mothers group received snacks that be consumed daily, which provided 600 kcal energy-with 25-30% energy derived from fats (150-180 kcal) 13% protein (80...
Introduction Women of reproductive age (WRA) are a high-risk population for anaemia and micronutrient deficiencies. Evidence supports the role periconceptional nutrition in development adverse pregnancy complications. However, India, there limited population-based data to guide evidence-based recommendations priority setting. The objective this study is conduct biomarker survey vitamin B 12 folate status WRA as part surveillance programme Southern India. Methods (15–40 years) who not...
A large proportion of infants in low- and middle-income countries are stunted. These often fed complementary foods that low-quality, primarily terms protein micronutrients. We aimed to test 2 milk–cereal mixes supplemented with modest high amounts during 6–12 mo age, compared no supplementation, for their effect on length-for-age z score (LAZ) at 12 age. Eligible (6 plus ≤29 d) were randomly assigned either the interventions (modest- high-protein) or a supplement group. The provided ∼125...
Objective: To examine the prevalence and determinants of poor infant vitamin B12 status at birth, determine associations between maternal status. Methods: 366 pregnant women participating in a supplementation trial India were monitored to assess pregnancy its association with 6 weeks age. Binomial linear regression used evaluate Results: 51% mothers deficient (<150pmol/L) baseline, 47% infants Maternal concentrations during 3 trimesters (T) significantly correlated (T1: r=0.19, p=0.10;...
Undetected onset of sarcopenia among individuals with chronic diseases especially Type 2 Diabetes Mellitus (T2D) makes it important to be evaluated. The feasibility diagnosing in a clinical setup might difficult task. Circulating markers including C-terminal agrin fragment (CAF) are emerging as an alternative. Hence, the objectives study were compare circulating CAF levels between T2D, prediabetes (PD) and healthy controls its association sarcopenic index, muscle mass, strength...
Objective: To examine the burden of anemia and iron deficiency its association with pregnancy outcomes in women India. Methods: A total 366 pregnant who were participating a vitamin B12 supplementation trial India monitored to assess associations maternal hematological status during (hemoglobin, ferritin, CRP, AGP) birth outcomes. Binomial linear regression models used evaluate between Results: Anemia common pregnancy: 30% anemic (Hb<11.0 g/dL), 40% deficient (ferritin<12 µg/L), 22%...
Abstract Objectives: To assess the impact of nutritional and multiple-micronutrient supplementation to lactating mothers on micronutrient status mother–infant dyad at 6 months age postnatally. Design: This study was a trial that aimed investigate maternal infant growth. A secondary objective effect pairs. The intervention group received snacks with 600 kcal energy, 20 g protein daily tablets. Setting: Blood samples were collected from both infants months. Participants: participants in this...
To conduct a biomarker survey to examine the anemia burden and vitamin B12 folate status in women of reproductive age as part an ongoing periconceptional surveillance program Southern India. Participants were (15–40 y) who not pregnant or lactating resided households within 50 km2 catchment area our community-based research site Venous blood samples collected at enrollment (n = 813), whole analyzed for hemoglobin using automated Coulter counter. Plasma, serum, red cells (RBC) separated by...
To conduct a biomarker survey to examine the burden of anemia, iron deficiency, and inflammation in women reproductive age Southern India. Participants were (15–40 y; n = 980) who not pregnant or lactating resided households within 50 km,2 catchment area our periconceptional surveillance program Venous blood samples collected at enrollment by trained laboratory technician research facility. Whole analyzed for hemoglobin (Hb) using an automated Coulter counter. Plasma, serum, red cells...
To examine the associations of iron status with metabolic health outcomes in women reproductive age (WRA), as part a population-based biomarker survey Southern India. Participants were WRA (15–40 y; n = 980) who not pregnant or lactating (2017–2018). Blood samples analyzed for hemoglobin (Hb; Coulter Counter) and glycated (HbA1c; nephelometry). Serum ferritin (SF) was measured by electrochemiluminescence; soluble transferrin receptor, C-reactive protein, alpha-1 acid glycoprotein via...
To evaluate anemia screening via portable hemoglobinometer (HemoCue 301) compared to automated hematology analyzer (AHA) reference, using paired venous samples from a population-based biomarker survey in Southern India. Participants were women of reproductive age (WRA; 15–40 y) who not pregnant or lactating. Paired whole blood (n = 896) analyzed for hemoglobin (Hb) HemoCue 301 and Coulter Counter AHA, as the gold standard. Serum ferritin (SF) was measured by electrochemiluminescence. Anemia...
Inadequate maternal choline intake during pregnancy has been associated with adverse and child health outcomes – identified as a potential risk factor for neural tube defects. However, there is limited data on biomarkers of metabolism in women reproductive age (WRA), few representative population-level from India. The objective this analysis was to examine their correlates WRA, part population-based biomarker survey Southern Participants were WRA (15–40y; n = 980) who not pregnant or...
To examine the burden of metabolic outcomes and associations vitamin B12 status with health in women reproductive age (WRA), as part a population-based biomarker survey Chittoor, India. Participants (980 WRA; 15–40y nonpregnant or lactating) were assessed for glycated hemoglobin (HbA1c; nephelometry) serum concentrations (chemiluminescence). Anthropometric measurements systolic (SBP) diastolic (DBP) blood pressures collected triplicate. Bioelectrical impedance analysis was used to evaluate...
To estimate the serum folate insufficiency threshold (sf-IT) corresponding to red blood cell (RBC) for optimal neural tube defect (NTD) prevention. Participants were 977 women of reproductive age (WRA; 15–40y; not pregnant or lactating) from a population-based biomarker survey in Southern India. Venous samples collected at enrollment. Plasma, serum, and cells centrifuged, processed, stored < -80°C until batch analysis. Total vitamin B12 concentrations measured via chemiluminescence; RBC...