A5085007503- Infant Nutrition and Health
- Breastfeeding Practices and Influences
- Birth, Development, and Health
- Child Nutrition and Water Access
- Neonatal Respiratory Health Research
- Infant Health and Development
- Child Nutrition and Feeding Issues
- Iron Metabolism and Disorders
- Diet and metabolism studies
- Pregnancy and preeclampsia studies
- Infant Development and Preterm Care
- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Folate and B Vitamins Research
- Nutritional Studies and Diet
- Fatty Acid Research and Health
- Gut microbiota and health
- Maternal Mental Health During Pregnancy and Postpartum
- Preterm Birth and Chorioamnionitis
- Neuroscience of respiration and sleep
- Diet, Metabolism, and Disease
- Pediatric health and respiratory diseases
- Agriculture Sustainability and Environmental Impact
- Congenital Anomalies and Fetal Surgery
- Organic Food and Agriculture
Nestlé (Switzerland)
2017-2024
St. John's National Academy of Health Sciences
2012-2014
Tampere University
2012
St. John's University
2011-2012
Human milk oligosaccharide (HMO) composition varies among lactating mothers and changes during the course of lactation period. Interindividual variation is largely driven by fucosyltransferase (FUT2 FUT3) polymorphisms resulting in 4 distinct groups. Little known regarding whether maternal physiological status contributes to HMO variability. We characterized trajectories 20 major HMOs explored pre-pregnancy body mass index (ppBMI), mode delivery, or parity may affect composition. Using...
Human milk (HM) composition is influenced by factors, like maternal diet and body stores, among other factors. For evaluating the influence of fatty acid (FA) status on FA composition, correlation between content in HM plasma, erythrocytes, adipose tissue was investigated.
While ample research on independent associations between infant cognition and gut microbiota composition human milk (HM) oligosaccharides (HMOs) has been reported, studies how the interactions HMOs may yield with cognitive development in infancy are lacking. We aimed to determine species of Bacteroides Bifidobacterium genera interact each other their typically developing infants. A total 105 mother-infant dyads were included this study. The enrolled infants [2.9–12 months old (8.09 ± 2.48)]...
<b><i>Aim:</i></b> To evaluate the vitamin B<sub>12</sub> status of South Indian women in early pregnancy and its relationship with sociodemographic, anthropometry dietary intake. <b><i>Methods:</i></b> Cross-sectional study among 366 pregnant urban ≤14 weeks gestation outcome variables defined as low blood concentration (<150 pmol/l) impaired [low plus elevated methylmalonic acid (MMA) >0.26 µmol/l)]....
Abstract Objective To identify correlates of anaemia during the first trimester pregnancy among 366 urban South Indian pregnant women. Design Cross-sectional study evaluating demographic, socio-economic, anthropometric and dietary intake data on haematological outcomes. Setting A government maternity health-care centre catering predominantly to needs women from lower socio-economic strata Bangalore. Subjects Pregnant ( n 366) aged ≥18 ≤40 years, who registered for antenatal screening at ≤14...
The effect of the mode neonatal delivery (cesarean or vaginal) on nutrient composition human milk (HM) has rarely been studied. Given increasing prevalence cesarean section (C-section) globally, understanding impact C-section vs. vaginal HM is fundamental when preferred source infant food during first 4 postnatal months.This study aimed to evaluate association between and in months life.Milk samples were obtained from 317 healthy lactating mothers as part an exploratory analyses within a...
Introduction Bifidobacterium longum subspecies infantis ( B. ) may play a key role in infant gut development. This trial evaluated safety, tolerability, and efficacy of LMG11588 supplementation. Methods randomized, placebo-controlled, double-blind study conducted the Philippines included healthy breastfed and/or formula-fed infants (14–21 days old) randomized for 8 weeks to control group (CG; n = 77), or any two experimental groups (EGs): low (Lo-EG; 1*10 CFU/day; 75) high dose (Hi-EG;...
Abstract Eating habits of lactating women can influence the nutrient composition human milk, which in turn influences intake breastfed infants. The aim present study was to identify food patterns and nutritional adequacy among Europe. Data from a multicentre European longitudinal cohort (ATLAS study) were analysed dietary using cluster analysis. Dietary information 180 obtained 3-d diaries over first 4 months lactation. Four identified: ‘vege-oils’, ‘fish-poultry’, ‘confectionery-salads’...
Abstract Zinc (Zn) deficiency in infancy and early childhood is of public health concern developing countries. This study aimed to longitudinally assess Zn intake urban South Indian term infants the first 6 months life using measures breast milk (BM) volume BM concentrations and, additionally, effect on infant length weight gain. by deuterium dilution technique, concentration at 1, 3 6, as well serum level were assessed 50 mother–infant pairs. significantly declined from 627 mL day −1 month...
Abstract Human milk oligosaccharides play a key role in the maturation of infant gut microbiome and immune system are hypothesized to affect growth. This study examined temporal changes 24 HMOs their associations growth appetitive traits an exploratory, prospective, observational, 41 Filipino mother-infant dyads. Exclusively breastfed, healthy, term infants were enrolled at 21–26 days age (≈ 0.75 mo) followed for 6 months. Infant measures collected visit 1 (V1) mo), V2 1.5 V3 (2.5 V4 (2.75...
Perinatal mood disorders such as depression and anxiety are common, with subclinical symptomology manifesting perinatal disturbances being even more prevalent. These could potentially affect breastfeeding practices infant development. Pregnant lactating women usually limit their exposure to medications, including those for psychological symptoms. Interestingly, the naturally occurring probiotic Bifidobacterium longum (BL) NCC3001 has been shown reduce anxious behavior in preclinical models...
Early dietary exposure via human milk nutrients offers a window of opportunity to support cognitive and temperament development. While several studies have focused on associations few pre-selected with cognition temperament, it is highly plausible that synergistically jointly behavioral development in early life. We aimed discern the combined three major classes during first 6 months life when primary source an infant’s nutrition explore whether there were persistent effects up 18 old. The...
Subclinical mastitis (SCM) is an inflammatory state of the lactating mammary gland, which asymptomatic and may have negative consequences for child growth. The objectives this study were to: (1) test association between dietary index (DII®) SCM (2) assess differences in nutrient intakes women without those with SCM. One hundred seventy-seven available data on human milk (HM) sodium potassium ratio (Na:K) intake included analysis. Multivariable logistic regression was used to examine DII...
Objective: To examine the prevalence and determinants of poor infant vitamin B12 status at birth, determine associations between maternal status. Methods: 366 pregnant women participating in a supplementation trial India were monitored to assess pregnancy its association with 6 weeks age. Binomial linear regression used evaluate Results: 51% mothers deficient (<150pmol/L) baseline, 47% infants Maternal concentrations during 3 trimesters (T) significantly correlated (T1: r=0.19, p=0.10;...
Objective: To examine the burden of anemia and iron deficiency its association with pregnancy outcomes in women India. Methods: A total 366 pregnant who were participating a vitamin B12 supplementation trial India monitored to assess associations maternal hematological status during (hemoglobin, ferritin, CRP, AGP) birth outcomes. Binomial linear regression models used evaluate between Results: Anemia common pregnancy: 30% anemic (Hb<11.0 g/dL), 40% deficient (ferritin<12 µg/L), 22%...
Background and objectives: Oral Nutritional Supplements (ONS) is shown to impact growth in nutritionally at-risk children, however, effects on developmental progress behavior are not well elucidated. We aimed assess the effect of ONS combined with dietary counselling (DC) achievement skills, temperament traits, parent-reported toddler quality life 1–3-year-old children ≤25th weight-for-length percentile. Methods: In this prospective single-arm, open-label intervention study (N = 108),...
Background and objectives: Adequate nutrition is a key determinant of growth in children, Oral Nutritional Supplement (ONS) represents an important strategy to improve nutritional adequacy nutritionally at-risk children. We aimed assess the effect ONS combined with dietary counselling (DC) on 1–3-year-old children ≤ 25th weight-for-length percentile. Methods: In this prospective single-arm, open-label intervention study (N = 108), received 2 servings/day plus DC for 16 weeks. The was energy...
This paper demonstrates how available data can be explored and utilized to conclude generic patterns in the temporal changes Human Milk (HM) composition.