A5078457446- Vibrio bacteria research studies
- Antibiotic Resistance in Bacteria
- Enzyme Structure and Function
- Protein Structure and Dynamics
- Biochemical and Molecular Research
- Polyamine Metabolism and Applications
- Bacterial biofilms and quorum sensing
- Carbohydrate Chemistry and Synthesis
Sichuan University
2021-2024
State Key Laboratory of Biotherapy
2021-2022
Bacterial type II toxin-antitoxin (TA) systems are abundant genetic elements and involved in a diverse array of physiological processes. These encode an antitoxin protein that directly binds effectively neutralizes the toxin. Recent studies have highlighted key roles TA modules bacterial virulence pathogenesis, but underlying mechanisms remain unclear. Here, we investigated HigA Pseudomonas aeruginosa infection. Proteomic analysis higA deletion strain revealed enhanced expression pathogenic...
β-N-acetylhexosaminidases (EC3.2.1.52), which belong to the glycosyl hydrolase family GH20, are important enzymes for oligosaccharides modification. Numerous microbial have been investigated applications in biology, biomedicine and biotechnology. Akkermansia muciniphila is an anaerobic intestinal commensal bacterium possesses specific gut mucosal layer colonization mucin degradation. In this study, we assessed vitro glycan cleavage activity of A. β-N-acetylhexosaminidase Am2136 demonstrated...