Markus Wirz

ORCID: 0000-0001-6716-8527
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About
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Research Areas
  • Stroke Rehabilitation and Recovery
  • Cerebral Palsy and Movement Disorders
  • Spinal Cord Injury Research
  • Medical Practices and Rehabilitation
  • Prosthetics and Rehabilitation Robotics
  • Health and Medical Studies
  • Muscle activation and electromyography studies
  • Musculoskeletal pain and rehabilitation
  • Balance, Gait, and Falls Prevention
  • Cardiac, Anesthesia and Surgical Outcomes
  • Nerve Injury and Rehabilitation
  • Enhanced Recovery After Surgery
  • Nutrition and Health in Aging
  • Spinal Dysraphism and Malformations
  • Psychiatric care and mental health services
  • Biomedical and Chemical Research
  • Acute Ischemic Stroke Management
  • Spine and Intervertebral Disc Pathology
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Long-Term Effects of COVID-19
  • Physical Activity and Health
  • Botulinum Toxin and Related Neurological Disorders
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cardiovascular and exercise physiology
  • Nursing Roles and Practices

ZHAW Zurich University of Applied Sciences
2015-2025

Sulzer (Switzerland)
2021-2025

University College London
2023

The Royal Free Hospital
2023

Universitätsklinik Balgrist
2006-2017

Maastricht University
2009-2011

Swiss Paraplegic Center
1997-2010

University of Zurich
2009

Persons with spinal cord injury who are able to walk at risk for falls.The objectives were investigate if the Berg Balance Scale (BBS) can discriminate those a propensity fall; determine whether BBS is associated mobility measures, fear of falling, and muscle strength; assess interobserver reliability.The measurement tools used BBS, Spinal Cord Independence Measure, Falls Efficacy (FES-I), Walking Index Injury, 10-m test, standard neurological classification including motor scores (MS)....

10.1177/1545968309341059 article EN Neurorehabilitation and neural repair 2009-08-12

Abstract Background The Swiss containment strategy for the COVID-19 pandemic during first wave in spring 2020 resulted a moratorium on non-urgent physiotherapy via regular direct patient contact. Consequently, such sessions declined by 84%. This study investigates impact of this use digital remote Switzerland period and perceptions its physiotherapists (PTs). Methods A cross-sectional online questionnaire was distributed between June August Physiotherapy Association (physioswiss) various...

10.1186/s40945-021-00112-3 article EN cc-by Archives of Physiotherapy 2021-07-07

<h3>Objective:</h3> This study aimed to evaluate the effects of mitochondrial pyruvate carrier (MPC) blockade on sensitivity detection and radiotherapy prostate cancer (PCa). <h3>Methods:</h3> We investigated glycolysis reprogramming MPC changes in patients with PCa by using metabolic profiling, RNA-Seq, tissue microarrays. Transient influx into mitochondria was observed cellular studies detect its different carcinoma cells benign cells. Xenograft mouse models were injected an inhibitor...

10.1136/jnnp.71.1.93 article EN Journal of Neurology Neurosurgery & Psychiatry 2001-07-01

AbstractAbstract Objectives: After a spinal cord injury (SCI), walking function is an important outcome measure for rehabilitation and new treatment interventions. The current status of four capacity tests that are applied to SCI subjects presented: the revised index (WISCI II), 6 minute walk test (6MinWT), 10 meter (10MWT) timed up go (TUG) test. Then, we investigated which categories WISCI II apply who participated in European Multicenter Study Human Spinal Cord Injury (EM-SCI),...

10.1179/016164107x230775 article EN Neurological Research 2008-02-01

Background. This study investigated whether loading the legs during swing phase of walking enhances flexor muscle activity in ambulatory patients with incomplete spinal cord injury (SCI). Methods. Nine had surface electromyography (EMG) and joint kinematics recorded from lower extremities treadmill walking. Swing was achieved by weights (1-3 kg) attached to each extremity or a velocity-dependent resistance applied Lokomat robotic gait orthosis. Results. When walked weights, there consistent...

10.1177/1545968308315595 article EN Neurorehabilitation and neural repair 2008-05-16

10.1016/s0924-980x(98)00002-2 article EN Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control 1998-04-01

The objective of this retrospective analysis was to determine whether outcome body functions and activities as well length stay inpatient rehabilitation is related age in patients with traumatic spinal cord injury (SCI). Data were collected from a European network 17 SCI centers (EM-SCI); total 237 subjects included. Assessments performed at 1, 6, 12 months after SCI. measures analyzed motor score according the American Spinal Injury Association, Cord Independence Measure (SCIM), gait speed,...

10.1089/neu.2008.0824 article EN Journal of Neurotrauma 2009-07-15

The neural control of "cooperative" hand movements reflecting "opening a bottle" was explored in human subjects by electromyographic (EMG) and functional magnetic resonance imaging (fMRI) recordings. EMG responses to unilateral nonnoxious ulnar nerve stimulation were analyzed the forearm muscles both sides during dynamic against torque applied right device which compensated for left hand. For control, stimuli while task performed static/isometric mode bilateral synchronous pro-/supination...

10.1093/cercor/bht285 article EN Cerebral Cortex 2013-10-11

The aim of this study was to evaluate the sensorimotor interactions between unaffected and affected sides post-stroke subjects during locomotion. In healthy subjects, stimulation tibial nerve mid-stance phase is followed by electromyography responses not only in ipsilateral tibialis anterior, but also proximal arm muscles both sides, with larger amplitudes prior swing over an obstacle compared normal swing. were stronger on when leg stimulated leg. This difference more pronounced stimuli...

10.1093/brain/awq370 article EN Brain 2011-02-08

A large proportion of patients with spinal cord injury (SCI) regain ambulatory function. However, during the first 3 months most are not able to walk unsupported. To enable training at such an early stage body weight is partially relieved and leg movements assisted by two therapists. more recent approach application robotic based assistance which allows for longer duration. From motor learning science studies including stroke, it known that effects depend on duration training. Longer...

10.1186/1471-2377-11-60 article EN cc-by BMC Neurology 2011-05-27

The aim of this study was to evaluate whether the effect longer training times (50 instead 25 min per day) using a robotic device results in better outcome walking ability subjects with subacute motor complete (American Spinal Injury Association Impairment Scale [AIS]-B) and incomplete (AIS-C) spinal cord injury. Twenty-one patients were enrolled study, whereof 18 completed, on average, 34 trainings 8 weeks. Longer resulted locomotor function. second important result is that beneficial can...

10.1089/neu.2016.4643 article EN Journal of Neurotrauma 2016-10-18

This retrospective study was designed to examine the influence of age on outcome motor function and activities daily living (ADLs) in patients with a cervical spinal cord injury (SCI). The is based data registry European Multicenter Study Spinal Cord Injury (EMSCI) group. Initial upper-extremity score (UEMS) its change over 5 months, as well initial Independence Measure (SCIM) score, did not differ between younger adults (20–39 years) elderly (60–79 patients. However, SCIM months...

10.1089/neu.2014.3335 article EN Journal of Neurotrauma 2014-06-25
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