A5091077519- Nasolacrimal Duct Obstruction Treatments
- Oral and Maxillofacial Pathology
- Sinusitis and nasal conditions
- Cancer and Skin Lesions
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Glaucoma and retinal disorders
- Ophthalmology and Eye Disorders
- Ocular Surface and Contact Lens
- Pneumothorax, Barotrauma, Emphysema
- Sympathectomy and Hyperhidrosis Treatments
Federal State Scientific Institution Research Institute of Eye Diseases
2015-2022
Helmholtz Moscow Research Institute of Eye Diseases
2015-2017
To study the antifibrotic effectiveness of mitomycin-C in tissues ostium site after it application for endonasal endoscopic dacryocystorhinostomy. The included 45 patients (48 cases) with primary obstruction nasolacrimal duct. All underwent dacryocystorhinostomy (EEDCR). At final stage operation, a swab MMC was placed region formed at concentration 0.2 mg/ml 3 min. An not intubated. After that, biopsies mucous nasal cavity and lacrimal sac were performed to morphological changes that occur...
Ostium closure due to local reparative processes is the most common cause of recurrence after endoscopic endonasal dacryocystorhinostomy (DCR), but as yet poorly studied.To perform morphological study at osteotomy site DCR.The included 18 patients (18 women) aged 62.59±10.07 years with nasolacrimal duct obstruction, who underwent DCR (P.J. Wormald modification). Osteotomy biopsies were taken on days 2, 5, 7, 10, 14, 21, 28, and 60 surgery. All samples stained haematoxylin eosin. For further...
Optical coherence tomography (OCT) based lacrimal meniscometry is currently the most accurate method used to determine dimensions of tear meniscus. According related literature, latter gets reliably reduced after treatment nasolacrimal duct obstructions. However, relationship between morphometric parameters meniscus and intensity epiphora has not been established. Even an adequate study parameter yet identified.To investigate significance OCT in determining extent insufficiency drainage.A...
to compare the effectiveness of balloon dacryoplasty (DCP) for stenoses at different levels vertical portion lacrimal pathways and establish necessity consequent intubation.A total 120 clinical cases in 85 patients (66 females 19 males with mean age 53.61 ± 11.82 years) have been analyzed. Patients cervical stenosis sac constituted two groups: group 1 (19 patients, 30 DCP surgeries) 2 (22 surgeries Ritleng intubation). Two other groups consisted nasolacrimal orifice stenosis: 3 (21 4 (23...
To develop the optimal protocol for balloon dacryoplasty (DCP) through an experiment.The experiment enrolled 12 Chinchilla rabbits (24 eyes). DCP group 1 (5 rabbits, 10 eyes) implied two dilations of 90 and 60 sec followed by another same duration, while in 2 all four were sec. The was moved proximally before every third dilation. remaining (4 who did not receive constituted control group. animals killed on days 1, 3, 7, 14. In cases nasolacrimal duct morphology studied.By day 14 after...
Objective. To develop a method for investigating the perculiarities of structure nasolacrimal duct orifice according to data multislice computed tomography (MSCT). Material and methods . The was investigated in 96 cases 65 people, including healthy volunteers (n=29), patients with dacryostenosis (n=45), those unilateral dacryocystitis (n=22). type identified using developed procedure on basis contrast-enhanced MSCT lacrimal passages. For verification, investigators used retrograde probing...
Mitomycin-C (MMC) is the most frequently used agent for prevention of excessive scarring at osteotomy site after endoscopic endonasal dacryocystorhinostomy (EEDCR), which, however, being applied during final stage surgery, shows questionable effectiveness.to evaluate effectiveness a new administration route mitomycin C in EEDCR.The study included 86 patients (95 cases) age range 62.3±9 years with primary acquired nasolacrimal duct obstruction. All underwent P.J. Wormald modification EEDCR...
Introduction. Mitomycin-C is an alkylating antibiotic used to prevent excessive scar formation in the dacryostoma area after dacryocystorhinostomy. In vitro studies proved its inhibition effect on fibroblast growth 0.2 mg/ml concentration. Up date, clinical data efficacy remain contradictory.
 Aim. To evaluate concentration of nasal cavity and lacrimal sac mucosa topical application determine this procedure.
 Materials methods. 30 patients with nasolacrimal duct obliteration...
Background. Outpatient care is not widely spread in modern dacryology. At the same time, its necessity increases. There are no evidences of balloon dacryoplasty (BDP) application Russian periodical literature. Material and methods. 50 surgical procedures 30 patients with partial nasolacrimal duct obliteration were performed, among them BDP without lacrimal pathways intubation (group 1) 20 bicanalicular Ritleng 2). Lacrimal scintigraphy, single photon emission computed tomography, combined...
To study the morphological features of regenerative processes in dynamics after dacryocystorinostomy (DCR) with use Mitomycin C (MMC).The includes 31 cases. All patients underwent endonasal endoscopic DCR. Group 1 included 16 cases who received MMC injections. 2 15 were treated on collagen sponge into area formed anastomosis. Biopsies for histological examination taken 2nd, 5th, 7th, 14th, 21st, 28th and 60th days surgery. The samples subjected to examination.Activated fibroblasts detected...