Lucila I. Castro‐Pastrana

ORCID: 0000-0001-6724-6441
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About
Contact & Profiles
Research Areas
  • Pharmaceutical studies and practices
  • Pharmaceutical Practices and Patient Outcomes
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Pharmacovigilance and Adverse Drug Reactions
  • Drug-Induced Adverse Reactions
  • Medication Adherence and Compliance
  • Patient Safety and Medication Errors
  • Intravenous Infusion Technology and Safety
  • Advanced Photocatalysis Techniques
  • Pharmaceutical Economics and Policy
  • Healthcare Technology and Patient Monitoring
  • Antibiotic Use and Resistance
  • Biosimilars and Bioanalytical Methods
  • Analytical chemistry methods development
  • Academic integrity and plagiarism
  • Statistical Methods in Clinical Trials
  • Environmental Science and Water Management
  • Cardiovascular Syncope and Autonomic Disorders
  • Tryptophan and brain disorders
  • Neuroblastoma Research and Treatments
  • Mobile Health and mHealth Applications
  • Patient Satisfaction in Healthcare
  • Advanced Drug Delivery Systems
  • Vitamin C and Antioxidants Research
  • Graphene and Nanomaterials Applications

Universidad de las Américas Puebla
2008-2023

Adama (Israel)
2019

Universidad de Las Américas
2014

University of the Americas
2014

The occurrence of hypersensitivity reactions including rare but life-threatening Stevens–Johnson syndrome (SJS) and drug-induced (HSS) limits the use anticonvulsant carbamazepine (CBZ). Human leukocyte antigen-B (HLA)-B*15:02 HLA-A*31:01 have been identified as predictive genetic markers for CBZ in Asian European patients. To replicate these associations pediatric patients from North America with a diverse ethnic background, we investigated HLA-B*15:02 42 children 91 CBZ-tolerant across...

10.1038/clpt.2013.55 article EN Clinical Pharmacology & Therapeutics 2013-03-18

The purpose of this study was to assess prescription rationality and most common errors at the primary care clinic a Mexican university.A retrospective drug utilization review indication-prescription type carried out. A random sample 370 medical records patients assisted over year period, were reviewed. Prescription appropriateness evaluated according variables: indication, dosage regimen, administration route, contraindications, interactions, medication duplicity, unnecessary or missing...

10.1590/s1516-93322008000100013 article EN Revista Brasileira de Ciências Farmacêuticas 2008-03-01

<p>Mediante sus efluentes, los hospitales contribuyen a la ocurrencia de microcontaminantes emergentes como fármacos, en el agua. Este trabajo cuantificó presencia nueve fármacos las aguas residuales tres privados México con 66, 92 y 120 camas, respectivamente. Las muestras se caracterizaron fisicoquímicamente y, empleando cromatografía líquida alta resolución acoplada espectrometría masas (UPLC-MS/MS), reportaron siguientes concentraciones máximas promedio: paracetamol...

10.4995/ia.2021.13660 article ES cc-by-nc-sa Ingeniería del agua 2021-01-29

The aim of the study was to investigate efficacy intravenous (IV) smart pumps with drug libraries and dose error reduction system (DERS) intercept programming errors entailing high risk for patients in an adult intensive care unit (ICU).A 2-year retrospective conducted ICU Hospital Juárez de México Mexico City evaluate impact IV pump/DERS (Hospira MedNet) technology implementation. We a descriptive analysis reports generated by system's software from April 2014 through May 2016. Our focused...

10.1097/pts.0000000000000374 article EN Journal of Patient Safety 2017-04-01

Drug utilization research (DUR) contributes to inform policymaking and strengthen health systems. The availability of data sources is the first step for conducting DUR. However, documents that systematize these in Latin American (LatAm) countries are not known. We compiled potential DUR LatAm region.A network experts from nine was assembled conducted: (i) a website search government, academic, private institutions; (ii) screening eligible sources, (iii) liaising with national...

10.1002/pds.5404 article EN cc-by-nc-nd Pharmacoepidemiology and Drug Safety 2021-12-27

Background: The use of smart pump technology has shown to be profitable in the intensive care unit (ICU) because it avoids costs from prevented medication errors and allows for savings on disposables medications by establishing standardized concentrations dosing units. Objective: objective study is evaluate economic impact implementation infusion pumps consumption intravenous (IV) solutions an ICU. Methods: A retrospective observational was conducted with a pre-post design. occurred adult...

10.1177/0018578718786943 article EN Hospital Pharmacy 2018-07-11

Epilepsy is a chronic neurological disease characterized by the presence of spontaneous seizures, with higher incidence in pediatric population. Anti-seizure medication (ASM) may produce adverse drug reactions (ADRs) an elevated frequency and high severity. Thus, objective present study was to analyze, through intensive pharmacovigilance over 112 months, ADRs produced valproic acid (VPA), oxcarbazepine (OXC), phenytoin (PHT), levetiracetam (LEV), among others, administered monotherapy or...

10.3390/children10111775 article EN cc-by Children 2023-11-01

Background: Quetiapine – an antipsychotic multidrug resistance protein 1 (MDR-1) substrate - has a large interindividual variability in its pharmacokinetics Objective: In order to unravel the true effect of MDR-1 activity plasma levels quetiapine, we studied bioavailability quetiapine healthy subjects with different transporter activity. Method: Fifty-four Mexican mestizo subjects, both male and female, median age 32, were enrolled study. Before starting clinical trial, flow cytometric...

10.2174/221155600501160602005451 article EN Current Psychopharmacologye 2016-06-01

Background. Chlorine dioxide (ClO 2 ) and its related compounds have been proposed as a treatment for several diseases; their popularity increased during the COVID-19 pandemic. This study aimed to identify, characterize, synthesize existing publications regarding ClO compounds' toxicity efficacy treatment. Material Methods. A scoping systematic review of animal human studies was carried out in PubMed EMBASE from origin October 20, 2020. Outcomes interest were compounds. After title,...

10.34141/ljcs8201440 article EN Latin American Journal of Clinical Sciences and Medical Technology 2023-02-24
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