A5059971786- Carcinogens and Genotoxicity Assessment
- Environmental Toxicology and Ecotoxicology
- Essential Oils and Antimicrobial Activity
- Plant tissue culture and regeneration
- Aluminum toxicity and tolerance in plants and animals
- Allelopathy and phytotoxic interactions
- Venomous Animal Envenomation and Studies
- Pesticide Exposure and Toxicity
- Arsenic contamination and mitigation
- Weed Control and Herbicide Applications
- Psidium guajava Extracts and Applications
- Pesticide and Herbicide Environmental Studies
- Plant Stress Responses and Tolerance
- Healthcare and Venom Research
- Radioactive contamination and transfer
- Insect and Pesticide Research
- Erythrocyte Function and Pathophysiology
- Plant nutrient uptake and metabolism
- Neurobiology and Insect Physiology Research
- Electrokinetic Soil Remediation Techniques
- Zebrafish Biomedical Research Applications
- Plant Micronutrient Interactions and Effects
- Toxin Mechanisms and Immunotoxins
- Botany, Ecology, and Taxonomy Studies
- Toxic Organic Pollutants Impact
Universidade Federal de Lavras
2013-2025
University Center of Brasília
2014
This study evaluated the toxicological and mutagenic potential of water samples from a Wastewater Treatment Plant (WWTP) in Lavras, Minas Gerais, Brazil. Samples were taken four sites: upstream stream (P1), downstream (P2), at entrance treatment station (P3), exit (P4). We conducted physicochemical analyses water, phytotoxicity tests on plants (Triticum aestivum, Pennisetum glaucum, Lactuca sativa, Raphanus sativus), cytogenotoxicity using onion roots (Allium cepa), Artemia salina...
Studies that help understand the mechanisms of action environmental pollutants are extremely important in toxicology. In this context, assays using plants as models stand out for their simplicity and low performance cost. Among used purpose, Allium cepa L. is model most commonly applied cytogenotoxic tests, while Lactuca sativa L., already widely phytotoxic investigations, has been gaining prominence cytotoxic analyses. The present study aimed to compare responses A. via macroscopic (root...
Corn is the second most cultivated crop in Brazil, number-one country pesticide consumption. Chemical control of weeds performed using herbicides such as S-metolachlor with pre- and post-emergence action thus toxicity constitutes a matter great concern. The present investigation aimed to examine effects an S-metolachlor-based herbicide on Lactuca sativa L. (lettuce) Zea mays (maize) utilizing various bioassays. test solutions were prepared from commercial products containing active...
Spent pot-liner (SPL) is a hazardous solid waste produced by the aluminum industry. Although its composition may vary, fluoride and cyanide salts as well are predominant components. A seed-germination root-elongation test was performed with Lactuca sativa seeds system. SPL induced decrease of seed germination rate root elongation. The concentration 26.5g/L established from regression curve IC50 (inhibition 50%). Through chemical analyses, concentrations fluoride, in solutions (IC50),...
Jatropha curcas L. (Euphorbiaceae) is important for biofuel production and as a feed ingredient animal. However, the presence of phorbol esters in oil cake renders seeds toxic. The toxicity J. currently assessed by testing animals, leading to their death. identification toxic nontoxic improved varieties safe use byproducts avoid environmental toxicity. Hence, aim this study was propose short-term bioassay using plant model screen without need sacrifice any animals. evident germination, root...
Infusions of the leaves and seeds Annona crassiflora Mart. are commonly employed in treatment diarrhoea, snakebites, tumours disorders hair scalp. The aim present study was to investigate cytotoxic genotoxic properties ethanolic extracts A. by evaluating their effects on germination, root elongation, chromosome structure cell division Lactuca sativa (lettuce). experiment followed a randomized design involving L. with from applied at ten concentrations (0.0125, 0.025, 0.05, 0.1, 0.2, 0.4,...
The objective of this study was to evaluate the cytogenotoxic effects essential oil (EO) extracted from Backhousia citriodora L. (Myrtaceae) on plant model Lactuca sativa EO obtained through hydrodistillation, using a modified Clevenger apparatus (2 h), and subsequently analyzed by GC/MS GC-FID. Germinated seeds with root length 1–2 mm were exposed different concentrations (5, 25, 50, 100, 200 500 μg mL− 1) for 48 h. Distilled water used as negative control. Cytogenetic analyses, cell cycle...
Guava (Psidium guajava L.) is a plant often employed in popular medicine. Recently several studies have alerted about the toxicity of substances present medicinal plants, which can pose risks to human health. In this sense, work aimed investigate phytotoxic, cytotoxic and genotoxic action three guava varieties - Paluma, Pedro Sato Roxa ("purple") on test system Lactuca sativa L. Thus, macro- microscopic evaluations were carried out for five infusion concentrations (2.5, 5.0, 10.0, 20.0 40.0...
DNA damage is considered an important initial event in carcinogenesis. A considerable battery of assays exists to detect antimutagenic potential by exposure genotoxic agents combination with a plant compound. Plant systems such as Lactuca sativa have been successfully employed cytogenetic bioassays models properties. Psidium guajava (guava) fruit species In order better understand these properties and warrant guava use anticancer other degenerative diseases agent, the present work aimed...
The effects of Tityus serrulatus venom was accessed on the cell cycle and genetic material Lactuca sativa L. compared with damages to human leukocytes, in order evaluate genotoxic mutagenic potential toxins types very different. occurrence alterations DNA fragmentation evaluated sativa. Incubations leukocytes were also held subsequent evaluation proliferation index, micronucleus fragmented DNA. T. showed cytogenotoxic, reducing mitotic index induced micronuclei formation. death evidenced by...
The venoms of wasps are a complex mixture biologically active compounds, such as low molecular mass peptides, and proteins. aim the study was to evaluate action wasp venoms, Polybia occidentalis fastidiosa, on DNA human leukocytes cell cycle genetic material plant model Lactuca sativa L. (lettuce). cultured were treated with then evaluated by comet assay. On another assay, seeds exposed venom solution; emitted roots collected occurrence alterations (CCAs) fragmentation agarose gel...
In order to test the assumption that red blood cell (RBC) uridine diphosphate galactose content is regulated in part by dietary and help comprehend factors influencing RBC white (WBC) hexose concentrations vivo, oral loading studies were performed with 50 g of or 75 glucose normal adults. While elevations did not influence WBC UDPhexose levels, increased caused transient increases both UDPgalactose. WBC, UDPgalactose-4-epimerase was rate limiting. comparison RBC, had larger changes...
Brazil is the number-one country in pesticide consumption, and corn second most cultivated crop country. Chemical control of weeds associated with cultivation performed by application herbicides pre- postemergence action, such as S-metolachlor. Currently, toxicity a task great concern. In this regard, present study aimed to evaluate effects an S-metolachlor-based herbicide through bioassays plant model Lactuca sativa L. (lettuce) Zea mays (maize). The herbicidal test solutions containing...