A5033675451- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Acute Myocardial Infarction Research
- Emergency and Acute Care Studies
- Heart Failure Treatment and Management
- Clinical practice guidelines implementation
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Telemedicine and Telehealth Implementation
- Neurological Complications and Syndromes
- Patient Satisfaction in Healthcare
- Blood Coagulation and Thrombosis Mechanisms
- CNS Lymphoma Diagnosis and Treatment
- Hip and Femur Fractures
- COVID-19 Clinical Research Studies
- Asthma and respiratory diseases
- Spinal Dysraphism and Malformations
- Appendicitis Diagnosis and Management
- Autoimmune and Inflammatory Disorders Research
- Mobile Health and mHealth Applications
- Omental and Epiploic Conditions
- Allergic Rhinitis and Sensitization
- Long-Term Effects of COVID-19
Kaiser Permanente
2022-2025
Kaiser Permanente Vallejo Medical Center
2023-2025
Colorado Permanente Medical Group
2023-2025
University of California, Davis
2017-2024
Kaiser Permanente Oakland Medical Center
2024
Kaiser Permanente Vacaville Medical Center
2023
University of California Davis Medical Center
2017-2021
Albert Einstein College of Medicine
2018
University of California, San Francisco
2016
Dry eye disorders, including Sjögren's syndrome, constitute a common problem in the aging population, with limited effective therapeutic options available. The cAMP-activated Cl2 channel cystic fibrosis transmembrane conductance regulator (CFTR) is major prosecretory at ocular surface. We investigated whether compounds that target CFTR can correct abnormal tear film dry eye. Small-molecule activators of human wild-type identified by high-throughput screening were evaluated cell culture and...
Physicians commonly hospitalize patients presenting to the emergency department (ED) with acute pulmonary embolism (PE), despite eligibility for safe outpatient management. Risk stratification using electronic health record-embedded clinical decision support systems can aid physician site-of-care decision-making and increase The long-term sustainability of early improvements after cessation trial-based, champion-led promotion is uncertain.To evaluate recommended 4 years initial interventions...
Over 300,000 patients in the United States sustain low-trauma fragility hip fractures annually. Multidisciplinary geriatric fracture programs (GFP) including early, multimodal pain management reduce morbidity and mortality. Our overall goal was to determine effects of a GFP on emergency department (ED) fractures.We performed retrospective study age ≥65 years with two before after implementation GFP. Outcomes were time (any) first analgesic, use acetaminophen fascia iliaca compartment block...
Emergency department (ED) providers play an important role in the management of patients with acute heart failure (AHF). We present findings from a pilot study electronic decision support that includes personalized risk estimates using STRIDE-HF tool and tailored recommendations for initiating guideline directed medical therapy (GDMT) among appropriate patients.
Importance Clinical decision support (CDS) could help emergency department (ED) physicians treat patients with heart failure (HF) by estimating risk, collating relevant history, and assisting medication prescribing if physicians’ perspectives inform its design implementation. Objective To evaluate CDS usability workflow integration in the hands of ED physician end users who use it clinical practice. Design, Setting, Participants This mixed-methods qualitative study administered...
Patients with heart failure (HF) are a medically complex population frequent hospitalizations. Downstream health care utilization following primary delivered by telemedicine compared to in-person is unknown.
Importance Telemedicine is an increasingly used yet understudied vehicle to deliver pediatric primary care. Evidence detailing downstream health care utilization after telemedicine visits needed. Objective To compare conducted via (video or telephone) with in-person office regard physician medication prescribing and imaging laboratory ordering follow-up visits, emergency department (ED) hospitalizations. Design, Setting, Participants This cohort study included all patients younger than 18...
The optimal diagnostic workup of pulmonary embolism (PE) in the emergency department (ED) remains debated and traditionally uses a sequential approach with evaluation clinical probability, followed by D-dimer testing, chest imaging, or both. Scores such as Wells score were developed to limit number patients who undergo imaging (computed tomography ventilation–perfusion scanning) ruling out PE normal blood test. Although original motivation reduce was costs radiation, more recently decision...
Abstract Background Coronavirus disease 2019 (COVID‐19), the caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has extracted devastating tolls. Despite its pervasiveness, robust information on characteristics in emergency department (ED) and how that predicts clinical course remain limited. Methods We conducted a retrospective cohort study of first ED visit from SARS‐CoV‐2‐positive patients our health system, February 21, 2020 to April 5, 2020. reviewed each patient's...
In this article, we describe a novel case of SARS‐CoV‐2‐associated‐hemophagocytic lymphohistiocytosis (HLH) complicated by posterior reversible encephalopathy syndrome (PRES). Initially diagnosed with multisystem inflammatory response in children (MIS‐C), the patient received large corticosteroid dose days before onset neurological symptoms. After developing PRES, was treated antihypertensives, antiepileptics, dexamethasone, and anakinra, leading to neurologic normalization. We propose that...
Abstract Background Deaths from high‐risk pulmonary embolism (PE) appear to have increased in the US over last decade. Modifiable risks contributing this worrisome trend present opportunities for physicians, researchers, and healthcare policymakers improve care. Methods We sought contextualize contemporary, PE epidemiology examine clinical trials, quality improvement opportunities, policy initiatives directed at reducing mortality. Results observed significant modifiable excess mortality due...
In the emergency setting, diagnosis of benign causes acute abdominal pain can prevent unnecessary medical interventions. To illustrate this point, we report case a 28-year-old man who presented to emer- gency department with symptoms suggestive diverticulitis. Abdominal computed tomography (CT) established, instead, primary epiploic appendagitis (PEA), which was managed expectantly. The patient’s resolved within one week hospital discharge and he remained free at five-month phone follow-up....