I-Chun Lin

ORCID: 0000-0001-6775-8914
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About
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Research Areas
  • Corneal surgery and disorders
  • Ophthalmology and Visual Impairment Studies
  • Nonmelanoma Skin Cancer Studies
  • Oral Health Pathology and Treatment
  • Nail Diseases and Treatments
  • Herpesvirus Infections and Treatments
  • Drug-Induced Adverse Reactions
  • Skin Diseases and Diabetes
  • Down syndrome and intellectual disability research
  • Health Systems, Economic Evaluations, Quality of Life
  • Cutaneous lymphoproliferative disorders research
  • Advanced Photocatalysis Techniques
  • Eosinophilic Disorders and Syndromes
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Dental Radiography and Imaging
  • Rabies epidemiology and control
  • Respiratory Support and Mechanisms
  • Intraocular Surgery and Lenses
  • Acne and Rosacea Treatments and Effects
  • Medical Research and Treatments
  • Electronic Health Records Systems
  • Artificial Intelligence in Healthcare
  • Cardiac Structural Anomalies and Repair
  • Mast cells and histamine
  • Gastroesophageal reflux and treatments

Kaiser Permanente
2022-2025

Fudan University
2024-2025

University College London
2025

National Health and Family Planning Commission
2025

Kaohsiung Chang Gung Memorial Hospital
2012-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Eye & ENT Hospital of Fudan University
2024

Shanghai Clinical Research Center
2024

National Taiwan University Hospital
2014-2024

Feng Chia University
2023

Abstract Background Herpes zoster (HZ)-associated pain causes a significant burden on patients and healthcare resources. Treatment options for post-herpetic neuralgia (PHN) is limited, treatment course could be refractory. The consensus that preventing the progression of acute to PHN preferable treating itself. In clinical practice, anticonvulsants such as gabapentin pregabalin have been reported reduce severity duration from HZ lowered risk PHN. Tricyclic antidepressants, including...

10.1093/ijnp/pyae059.415 article EN cc-by-nc The International Journal of Neuropsychopharmacology 2025-02-01

This study aimed to analyze the impact of long-term ICL implantation on lens density, focusing relationship between anterior subcapsule, and implantable collamer lenses (ICL) position after V4c implantation. retrospective included 145 eyes with average follow-up 4.2 years (range: 3-8 years). The control group comprised 65 myopic without surgery. All participants underwent comprehensive ophthalmologic examinations, density were measured using quantitative Scheimpflug images. central...

10.2147/opth.s500512 article EN cc-by-nc Clinical ophthalmology 2025-02-01

Background Adverse events following mRNA COVID-19 vaccines, including herpes zoster (HZ), have been reported. We conducted a cohort study to evaluate the association between vaccination and subsequent HZ at Kaiser Permanente Southern California (KPSC).Research design methods The vaccinated consisted of KPSC members who received their first dose vaccine (mRNA-1273 BNT162b2) during 12/2020–05/2021 were matched unvaccinated individuals on age sex. Incident cases occurring within 90 days...

10.1080/14760584.2023.2232451 article EN cc-by-nc Expert Review of Vaccines 2023-07-07

What is known and Objective Myocarditis that develops because of the drug reaction with eosinophilia systemic symptoms (DRESS) syndrome a life-threatening disease. We report case DRESS-associated myocarditis cardiac failure required extracorporeal membrane oxygenation (ECMO) for cardiovascular support. Case summary A 14-year-old boy experienced after anticonvulsive therapy carbamazepine, clonazepam phenytoin. The clinical signs included hypotension, arrhythmia poor left ventricular (LV)...

10.1111/jcpt.12025 article EN Journal of Clinical Pharmacy and Therapeutics 2012-11-22

Abstract Background Esophageal achalasia, a primary disorder impacting the lower esophageal sphincter (LES), presents symptoms such as dysphagia, regurgitation, chest pain, and weight loss. Traditional treatments, including calcium channel blockers nitrates, offer limited relief, prompting exploration into alternative therapies. This study examines efficacy of Chinese Medicine (TCM), focusing on Coptis chinensis ( C. ) its principal component, berberine, for modulating LES relaxation,...

10.1186/s12906-024-04720-x article EN cc-by BMC Complementary Medicine and Therapies 2024-12-18

Abstract Background Oncologic treatments may lead to the development of paronychia, which cause severe pain and disability. However, a detailed objective scoring system is lacking. Objective To develop an quantify severity paronychia also examine correlation this score with index patients’ quality life. Methods A novel for related oncologic ( SPOT ), consisting four parameters, namely redness, oedema, discharge granulation tissue, was designed assess paronychia. The visual analogue scale VAS...

10.1111/jdv.15121 article EN Journal of the European Academy of Dermatology and Venereology 2018-06-12

Verrucous carcinoma is a rare variant of well-differentiated squamous cell with locally aggressive and minimal metastatic potential.1 Oral verrucous (OVC) the most common type in head neck regions accounts for 55.9% 2350 such cases.1 The overall 5-year survival rate OVC approximately 50% retrospective cohort study.2 risk factors include chronic inflammation induced by chemical carcinogenesis associated betel quid chewing, smoking, human papillomavirus infection, immunosuppression.

10.1016/j.jdcr.2018.02.002 article EN cc-by-nc-nd JAAD Case Reports 2018-06-12

Down syndrome (DS) is associated with an increased risk of infections attributed to immune defects. Whether individuals DS are at severe coronavirus disease 2019 (COVID-19) remains unclear.In a matched cohort study, we evaluated the COVID-19 infection and in their counterparts pre-COVID-19 vaccination period Kaiser Permanente Southern California. Multivariable Cox proportion hazard regression was used investigate associations between disease.Our included 2541 10 164 without on age, sex,...

10.1093/infdis/jiac236 article EN The Journal of Infectious Diseases 2022-06-24

<title>Abstract</title> Purpose To evaluate the efficacy of EVO-ICL implantation combined with a corneal relaxing incision for correction moderate to high myopia low astigmatism. Design: prospective non-randomized clinical trial Methods This study included 35 eyes patients astigmatism corrected by (CRI) on steep meridian and 30 who underwent conventional temporal as controls. Visual acuity, refractive parameters, keratometry, astigmatism, aberration were measured preoperatively 1 3 months...

10.21203/rs.3.rs-5318786/v1 preprint EN cc-by Research Square (Research Square) 2024-11-19

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

10.2139/ssrn.4687236 preprint EN 2024-01-01

Artificial intelligence systems, particularly large language models (LLMs), are increasingly being employed in high-stakes decisions that impact both individuals and society at large, often without adequate safeguards to ensure safety, quality, equity. Yet LLMs hallucinate, lack common sense, biased - shortcomings may reflect LLMs' inherent limitations thus not be remedied by more sophisticated architectures, data, or human feedback. Relying solely on for complex, is therefore problematic....

10.48550/arxiv.2406.14981 preprint EN arXiv (Cornell University) 2024-06-21

10.1016/j.jmii.2015.02.329 article EN publisher-specific-oa Journal of Microbiology Immunology and Infection 2015-03-28

A multi-step procedure was effectively employed to synthesize innovative three-dimensional (3D) heterostructures encompassing sodium titanate (Na2Ti3O7) nanowire cores, an intermediate resorcinol–formaldehyde (RF) layer, and outer silver (Ag) nanoparticle sheaths, referred as Na2Ti3O7@RF@Ag heterostructures. Initially, a one-step hydrothermal technique facilitated the direct growth of single-crystal Na2Ti3O7 nanowires onto flexible Ti foil. Subsequently, two-step wet chemical process...

10.3390/molecules29010218 article EN cc-by Molecules 2023-12-30
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