- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Ocular Infections and Treatments
- Ocular Surface and Contact Lens
- Retinal and Macular Surgery
- Ocular and Laser Science Research
- Spinal Fractures and Fixation Techniques
- Hepatitis B Virus Studies
- Cancer Mechanisms and Therapy
- Retinal Imaging and Analysis
- Spine and Intervertebral Disc Pathology
- Retinal Diseases and Treatments
- Lung Cancer Treatments and Mutations
- Tuberculosis Research and Epidemiology
- Impact of Light on Environment and Health
- Mycobacterium research and diagnosis
- Liver Disease Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Advanced SAR Imaging Techniques
- Salivary Gland Tumors Diagnosis and Treatment
- Retinopathy of Prematurity Studies
- Antimicrobial agents and applications
Shanghai Clinical Research Center
2020-2025
Eye & ENT Hospital of Fudan University
2016-2025
Fudan University
2012-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Shanghai Eye Disease Prevention & Treatment Center
2021-2025
North China Electric Power University
2012-2025
Tulane University
2024-2025
National Health and Family Planning Commission
2021-2025
Xidian University
2025
Ningbo University
2024
In the realm of online learning, where resources are abundant, it is essential to customize recommendations and plans meet individual learning needs. This involves not only identifying addressing areas weakness but also aligning journey with each learner’s cognitive preferences. However, existing methods for suggesting structuring paths have notable limitations. To address these challenges, this paper introduces a knowledge graph-based personalized path planning method (KG-PLPPM). By...
To objectively compare the early changes in vault over time following implantation of an Implantable Collamer Lens without (ICL V4) and with V4c) a central hole respective factors affecting change moderate to high myopia.This prospective study comprised 38 eyes patients implanted ICL V4 39 V4c intraocular lenses. We quantitatively assessed postoperative values pupil size at 1 day, week, month using rotating Scheimpflug camera (Pentacam). compared these within between two groups identified...
Abstract Purpose To investigate differences in the objective and subjective visual quality of patients with high myopia following implantable collamer lens V4c (ICL V4c) versus small incision lenticule extraction (SMILE) early postoperatively. Methods This prospective analysis included 94 eyes 57 (8 males) ICL group (mean spherical equivalent (SE), −8.07 ± 1.03 dioptres (D)) 103 (13 SMILE SE, −7.85 0.78 D). Refractive parameters wavefront aberrations were recorded preoperatively 6 months...
To investigate refractive outcomes and optical quality after implantation of posterior chamber phakic implantable collamer lens with a central hole (ICL V4c) to correct high myopia.Sixty seven eyes 38 patients who underwent ICL V4c were enrolled. The mean preoperative spherical equivalent (SE) was - 12.44 ± 3.15 D (range: 6.63 20.50 D). the at postoperative 1 3 months evaluated compared.At postoperatively, safety efficacy indexes 1.33 0.22 1.14 0.23, respectively. SE 0.32 0.52 D; no patient...
To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. This cross-sectional study included 72 patients high myopia (134 eyes) who were followed up after phakic lens implantation. The postoperative time ranged from 1 week to 7 years. We obtained images ICL by using Compact Touch STS UBM observed position in chamber ciliary sulcus. horizontal lines vault was measured recorded. There various as full-scale ultrasound...
To predict the vault and EVO-implantable collamer lens (ICL) size by artificial intelligence (AI) big data analytics.Six thousand two hundred ninety-seven eyes implanted with an ICL from 3536 patients were included. The values measured anterior segment analyzer (Pentacam HR). Permutation importance Impurity-based feature are used to investigate between input parameters. Regression models classification applied vault. is set as target of prediction, other features new inputs for prediction....
Abstract Purpose To compare one‐year visual outcomes and optical quality after femtosecond laser small incision lenticule extraction (SMILE) Visian Implantable Collamer Lens with a central hole (ICL V4c) implantation for high myopia. Methods This prospective non‐randomized study included 37 eyes of 20 patients who underwent SMILE (G‐S) 39 ICL V4c (G‐V). Spherical equivalent (SE), uncorrected distance acuity, corrected retinal image intraocular scattering were evaluated at one year surgery....
Background To evaluate the changes in corneal endothelium cell density (ECD) and correlated factors after Implantable Collamer Lens (ICL) V4c implantation. Methods In this retrospective, consecutive study, 48 eyes of 25 patients with myopia who underwent ICL implantation were enrolled. Patients followed up for at least 4 years, during which manifest refraction, uncorrected distance visual acuity, corrected acuity (CDVA), intraocular pressure, ECD, anterior chamber depth, volume (ACV), angle...
Purpose: To evaluate the incidence, causes, and outcomes of implantable collamer lens (ICL) realignment or exchange after implantation EVO-ICL. Setting: Eye ENT Hospital Fudan University, China. Design: Retrospective study. Methods: The study included 10 258 consecutive eyes ICL implantation. Preoperative refractive biometric measurements were compared between with without exchange. For exchange, visual also before Results: overall incidence was 0.21% 22 eyes. 12 (0.12%) underwent by axis...
A series of ruthenium(II) bis(2,2′-bipyridyl) complexes containing N-phenyl-substituted diazafluorenes (Ru-C1, Ru-C6, Ru-C7 and Ru-F) was synthesized their potential antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) investigated. The complex showed significant improvement in both minimum inhibitory concentration (MIC, 6.25 μg mL−1) bactericidal (MBC, 25 towards MRSA when compared with those (positive control) (MIC = mL−1 MBC 100 mL−1). possessed much stronger...
Purpose To determine the incidence and clinical features of diffuse lamellar keratitis (DLK) after small-incision lenticule extraction (SMILE). Setting Department Ophthalmology, Eye ENT Hospital Fudan University, Shanghai, China. Design Retrospective case control study. Methods Small-incision for myopia was performed from September 1, 2011, to October 31, 2013. Preoperative characteristics; treatment parameters; intraoperative postoperative complications, including incidence, severity,...
Purpose To investigate the long-term safety, efficacy, stability, vault, and complications of implantable collamer lens with (ICL V4c) without V4) a central hole for correcting high myopia.Methods 78 eyes (40 patients) underwent ICL V4c implantation (48 V4 were enrolled. They followed up 5 years uncorrected corrected distance visual acuity, spherical equivalent (SE), axial length, intraocular pressure, endothelial cell density vault.ResuIts The safety indices groups at 1.25 ± 0.40 1.31 0.40,...
To evaluate the long-term safety, efficacy, predictability, and stability of implantable collamer lens with a central hole (EVO ICL) implantation for correcting high myopia (HM) super (SHM).This prospective study evaluated 83 eyes 46 patients who were divided into groups based on their spherical equivalent refractive error (SE): HM group (- 12 D ≤ SE < - 6 D) SHM (SE D). They followed up 5 years after ICL implantation; assessments uncorrected distance visual acuity (UDVA), corrected (CDVA),...
Intercropping (IC) has been widely adopted by farmers for enhancing crop productivity and economic returns; however, the underpinning mechanisms from perspective of below-ground interspecific interactions are only partly understood especially when intercropping practices under saline soil conditions. By using permeable (100 μm) impermeable (solid) root barriers in a multi-site field experiment, we aimed to study impact root-root on nutrient accumulation, microbial communities, yield, returns...
To evaluate the biosafety, reduction in anterior capsule opacification, and fluctuation intraocular pressure (IOP) of a new phakic refractive lens (PRL) with sinusoidal drainage groove design. This self-controlled experiment was performed on eight eyes four rabbits. Each rabbit implanted PRL (PRL-S5) right eye conventional posterior chamber (PC-PRL) left eye. Slit-lamp examinations, optical coherence tomography, IOP evaluation were before surgery at 1 day, week, 3 months, 6 year...
To identify factors contributing to rapid axial length (AL) growth in children aged 3-9 years. Four thousand four hundred thirty-five were followed from 2019 2022. AL and corneal curvature measured using an IOLMaster 500, while refractometry visual acuity also assessed. Baseline data included demographics parental myopia status, with annual updates on height, weight behavioural factors. Latent class model was used discover trajectories, whereas multiple logistic regression determinants of...
To investigate the long-term safety and efficacy of using keratorefractive lenticule extraction (KLEx)-derived corneal stromal lenticules preserved in nutrient capsules for treatment diseases. Eye ENT Hospital Fudan University. Observational study. Ten eyes 10 patients with diseases (6 males, 4 females, age 38.10 ± 9.11 years, ) were treated phototherapeutic keratectomy combined epikeratophakia or intrastromal keratoplasty KLEx-derived lenticules. Corneal which used transplantation was...
This study aimed to analyze the impact of long-term ICL implantation on lens density, focusing relationship between anterior subcapsule, and implantable collamer lenses (ICL) position after V4c implantation. retrospective included 145 eyes with average follow-up 4.2 years (range: 3-8 years). The control group comprised 65 myopic without surgery. All participants underwent comprehensive ophthalmologic examinations, density were measured using quantitative Scheimpflug images. central...
To compare the long-term outcomes of monovision surgery using implantable collamer lens (ICL) V4c and femtosecond laser-assisted in situ keratomileusis (FS-LASIK) myopic patients with early presbyopia. This case series study included 48 eyes 24 (male/female: 10/14, mean age 45.50 ± 3.82 years) followed-up for 4.5 years (54.00 9.77 months). Patients were examined spherical equivalent, uncorrected distance visual acuity, corrected intraocular pressure, presbyopic add power, acuity (VA)...
To compare vault measurement using Pentacam (Oculus, Germany) and two optical coherence tomography (OCT) instruments, Casia2 (Tomey Corporation, Japan) RTVue (Optovue Inc. USA). This comparative study recruited 95 eyes of 50 patients (mean age: 28.40±4.51, male/female 15/35) who underwent implantable collamer lens (ICL) implantation for myopia correction. All a series ophthalmic examinations at 3 6 months postoperatively, the was measured three instruments in same order both follow-ups....
Ambient air pollution may exacerbate ocular conditions; however, comprehensive research on the effects of various pollutants remains limited. To evaluate association between multiple and incidence five common vision-threatening diseases: cataracts, glaucoma, macular degeneration, diabetic retinopathy, retinal detachment. Prospective cohort study METHODS: We included 114,930 participants with refractometry at baseline in this prospective based data from UK Biobank. Annual average...