- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Advanced Fiber Laser Technologies
- Intraocular Surgery and Lenses
- Visual perception and processing mechanisms
- Cardiac Health and Mental Health
- Semiconductor Lasers and Optical Devices
- Advanced Optical Sensing Technologies
- Ocular Infections and Treatments
- Retinopathy of Prematurity Studies
- Advanced Frequency and Time Standards
- Optical Network Technologies
- Retinal Imaging and Analysis
- Advanced Fiber Optic Sensors
- Heart Rate Variability and Autonomic Control
- Pelvic floor disorders treatments
- Retinal Development and Disorders
- Cardiovascular and exercise physiology
- Adipose Tissue and Metabolism
- Retinal and Macular Surgery
- Diet and metabolism studies
Eye & ENT Hospital of Fudan University
2018-2025
Fudan University
2019-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2025
Shanghai Eye Disease Prevention & Treatment Center
2022-2025
Shanghai Clinical Research Center
2018-2022
Beijing University of Posts and Telecommunications
2018-2021
China XD Group (China)
2019-2020
Heidelberg University
2019-2020
University Hospital Heidelberg
2019-2020
Aims To compare long-term clinical outcomes following small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia myopic astigmatism correction. Methods In this retrospective study, we enrolled a total of 101 patients (101 eyes) who underwent SMILE or FS-LASIK 3 years prior. Measured parameters included uncorrected distance visual acuity (UDVA), corrected (CDVA), manifest refraction corneal wavefront aberrations. Results No...
To predict the vault and EVO-implantable collamer lens (ICL) size by artificial intelligence (AI) big data analytics.Six thousand two hundred ninety-seven eyes implanted with an ICL from 3536 patients were included. The values measured anterior segment analyzer (Pentacam HR). Permutation importance Impurity-based feature are used to investigate between input parameters. Regression models classification applied vault. is set as target of prediction, other features new inputs for prediction....
To investigate the correlation between corneal densitometry, topographic parameters, and biomechanical properties in keratoconus.A total of 76 eyes keratoconus patients were enrolled this cross-sectional study. Corneal densitometry topography measured using Pentacam HR. CorVis ST.The values anterior 0 to 2 6 mm layers significantly correlated with maximum keratometry (R = 0.373, P 0.001 R 0.276, 0.016, respectively), thinnest thickness -0.331, 0.003 -0.234, 0.042, elevation 0.392, < 0.323,...
In China, approximately 30 and 70% of primary middle school students, respectively, have myopia, making myopia prevention control necessary. Eye-use behaviors are closely related to highlighting the importance determining behavioral compliance rates children. Parental awareness also affects children's behaviors. Therefore, we assessed myopia-related parental school-aged children in different city tiers China with refractive statuses. A population-based, cross-sectional study was conducted on...
Our previous survey identified a lack of knowledge myopia among Chinese parents. This research aims to update the characteristics parents' knowledge, attitude, and practice in control. A self-administered questionnaire was disseminated parents myopic children 16 hospitals from 11 provinces China. Comprehensive information regarding with collected, underlying correlations being analyzed. total 1266 valid questionnaires were collected. The concern over children's visual problems arose...
To investigate the association between myopic severity and retinal microvascular density, choroidal vascularity retrobulbar blood flow in adult anisomyopes.This study comprised 90 eyes of 45 anisomyopes who were recruited for Colour Doppler imaging (CDI) optical coherence tomography angiography (OCTA). The superficial vessel density (SVD), deep (DVD), thickness (ChT) vascularity, including total area (TCA), luminal (LA), stromal (SA) Choroidal Vascularity Index (CVI), measured using OCTA....
Aim To investigate the change in posterior corneal elevations (PCEs) of eyes with extremely high myopia 2 years after small incision lenticule extraction (SMILE). Methods We evaluated 39 patients spherical equivalent higher than −10.00 dioptres (D). Using a Scheimpflug camera (Pentacam), we measured PCEs at 1 day, 3 months, 6 months and SMILE. Another 34 who underwent femtosecond laser-assisted situ keratomileusis (FS-LASIK) were examined before, day long-term surgery as control group. For...
Abstract Background We aimed to compare the intraocular pressure (IOP) measurements by a dynamic Scheimpflug analyzer (Corvis ST), non-contact tonometer, and an ocular response after hyperopic small-incision lenticule extraction (SMILE). Methods Thirteen patients who underwent SMILE in one eye were enrolled prospectively. IOP corneal biomechanical parameters measured preoperatively at 1 week, month, 3 months postoperatively with tonometer (IOP NCT ), Corvis ST (biomechanical corrected...
To compare the long-term refractive effects of small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) on correction high myopia astigmatism.The Eye ENT Hospital Fudan University, Shanghai, China.Retrospective case series.Patients had SMILE or FS-LASIK for myopia. Subgroup analyses (-6.00 to -8.75 diopters [D]) extremely (≥-9.00 D) were performed. The main outcome measure was predictability, compared between groups. Secondary...
Purpose: To investigate long-term changes in corneal densitometry (CD) following small incision lenticule extraction (SMILE) vs. femtosecond laser-assisted LASIK (FS-LASIK) patients with myopia or myopic astigmatism. Methods: Prospective analysis was performed 66 eyes of 38 (13 males) who underwent SMILE and 54 29 (5 FS-LASIK. In all patients, an ocular examination preoperatively, at 6-12 months 5 years postoperatively. CD obtained the Pentacam Scheimpflug imaging system 0-2-mm, 2-6-mm,...
PURPOSE: To investigate morphological changes in the cornea and implanted lenticule patients with corneal ectasia after laser situ keratomileusis (LASIK) implantation using a from small incision extraction (SMILE). METHODS: Eight eyes of 8 LASIK 2015 to 2018 at Eye ENT Hospital Fudan Unversity were analyzed. For recipient eyes, lenticules transferred mean cryopreserved time 20 ± 21 days extracted SMILE donors exposed stromal bed lifting flaps flap was repositioned. Uncorrected corrected...
Abstract Background This study aimed to compare long-term postoperative quality of life and satisfaction differences between SMILE FS-LASIK for myopia correction. Methods cross-sectional enrolled patients under the age 39 years, who chose undergo or surgery both eyes 3 years previously. Patients completed a common vision test Quality Life Impact Refractive Correction (QIRC) questionnaire, together with surgical satisfaction, adverse symptoms subjective survey. preoperative corrected distance...
Significance: Our study found that SP-A1 (stiffness parameter at time of first applanation) was statistically different between post-laser-assisted subepithelial keratomileusis (LASEK) and post-small incision lenticule extraction (SMILE) eyes. The stiffness keratoconus lower than post-refractive surgery corneas. Purpose: To compare corneal biomechanics among post-SMILE, post-LASEK, keratoconic Methods: In this retrospective study, 36 eyes patients after SMILE, LASEK, with matching (±5 μm)...
To investigate the morphological changes of concave iris in myopic patients after EVO implantable collamer lens (ICL) implantation.EVO ICL candidates with posterior bowing were observed using ultrasound biometric microscopy (UBM) this prospective nonrandomized observational study. Forty enrolled, 20 group and other control group. None underwent laser peripheral iridotomy. All received preoperative postoperative examinations, which included uncorrected distance visual acuity (UDVA), corrected...
An 18-year-old man with keratoconus had epikeratophakia using small-incision lenticule extraction addition in the left eye, which a minimum corneal thickness of 356 μm. Accelerated (45 mW/cm2) transepithelial crosslinking was performed 1 month later. The patient followed for 3 years postoperatively. Examinations included anterior segment optical coherence tomography (AS-OCT), uncorrected (UDVA) and corrected (CDVA) distance visual acuities, subjective refraction, topographic changes. UDVA...
Identifying peripheral retinal lesions in high myopia patients before implantable collamer lens (ICL) surgery by nonmydriatic Optomap ultrawide field imaging.To investigate specificity and sensitivity of imaging for detecting ICL surgery.Hospital-based, cross-sectional study.A total 1725 myopic eyes 897 candidates were included this study.Patients with scheduled routine ophthalmic examination implantation. Nonmydriatic was applied potential surgery.Presence lesions.Of eyes, 344 (19.94%) had...
Abstract Background To investigate the impact of ablation ratio on 5-year postoperative posterior corneal stability in myopic eyes after small incision lenticule extraction (SMILE) and femtosecond laser-assisted situ keratomileusis (FS-LASIK) surgery. Methods A prospective, nonrandomized, cohort study: 80 43 patients underwent SMILE surgery 63 32 FS-LASIK at EYE & ENT Hospital, Fudan University. Ablation was defined as thickness (SMILE cases) or depth (FS-LASIK divided by central (CCT)....
Abstract Background To assess the effects of warm compress (WC) on tear film lipid layer, blink pattern and Meibomian gland function in patients with dry eye following femtosecond laser small incision lenticule extraction (SMILE) laser-assisted subepithelial keratomileusis (LASEK). Methods We enrolled 37 eyes participants, each for more than 2 years SMILE (25 eyes) or LASEK (12 eyes). WC was performed using a spontaneously heating mask. Tear break-up time (TBUT), layer thickness (TFLLT),...
Purpose To compare mydriatic and eye-steering ultrawide field imaging (UWFI) with standard non-mydriatic UWFI examination in detecting peripheral retinal lesions myopic patients. Methods Cross-sectional, observational study. 220 eyes of 110 patients known at least one eye under Goldmann three mirror contact lens were recruited. Non-mydriatic images taken centrally technique upper, lower, nasal temporal gazes Optomap (Daytona, Optos, UK). Mydriatic was captured central gaze four different...
To investigate the refractive and ocular biometric characteristics of children with mild hyperopia distinguish between non-myopic pseudomyopic eyes before cycloplegia.
Purpose: To evaluate the characteristics of peripheral anterior chamber measurements by Pentacam after posterior implantable collamer lenses (ICL) and toric ICL (TICL) with central hole (V4c) implantation. Methods: Prospective, non-randomized consecutive case series. Forty-six patients undergoing implantation in one eye (Group A) identically sized TICL contralateral B) Refractive Surgery Center Eye ENT Hospital Fudan University were prospectively included. According to ICL/TICL size, these...
Purpose. To compare the corneal biomechanical properties between post-LASIK ectasia and primary keratoconus. Methods. A total of 42 eyes patients with matching age central thickness (CCT) were divided into two groups according to diagnosis (PLE group; n = 21; range: 22–47 years) keratoconus (KC 21–47 years). The assessed using Scheimpflug-based technology (Corvis ST; Oculus Optikgeräte, Wetzlar, Germany). paired t-test linear regression analysis performed. Results. PLE group had...
Purpose: To evaluate the long-term safety, efficacy, predictability, and stability of small incision lenticule extraction (SMILE) for treatment high myopia myopic astigmatism greater than -10.0 D. Methods: This was a prospective study that incorporated 35 consecutive patients (35 eyes) undergoing SMILE from September 2015 to March 2016. These had mean preoperative spherical equivalent refraction -10.06±0.64 Patients were followed over four-year period assessed outcomes including uncorrected...
Investigating the impact of magnification correction in macular vessel density using optical coherence tomography angiography (OCTA) patients with anisometropia.Cross-sectional study. Totally 47 (11 male, 36 female) aged >18 years high myopia were analyzed. All underwent evaluation visual acuity, subjective refraction, and axial length. Anisometropia (n=37) was defined as a refraction difference between paired eyes ≥0.75 D. The control group (n=10) consisted ≤0.5 Superficial performed 3 mm ×...
Herein, we verify that a Raman/EDFA hybrid amplifier can improve the stability of fiber-optic time and frequency synchronization systems compared to Er 3+ -doped fiber (EDFA), owing its higher gain lower noise figure (NF) performance. We studied variation law Raman efficiency for (FRA) as function pump power input signal power, designed bidirectional amplifier, proved equivalent NF below 0 dB be obtained. Finally, amplifiers were EDFAs in free-running system. The transfer stabilities reached...