Purpose: To explore the characteristics of retinal, choroidal, and retrobulbar blood flows in myopic patients with posterior staphyloma (PS) using ultra-widefield optical coherence tomography angiography (UWF-OCTA) Color Doppler imaging (CDI). Methods: The retrospective cross-sectional study enrolled 134 adults high myopia from Eye ENT Hospital Fudan University December 2021 to September 2022. After propensity score matching, 45 eyes 30 32 were included PS non-PS (NPS) groups, respectively....

To investigate the association between myopic severity and retinal microvascular density, choroidal vascularity retrobulbar blood flow in adult anisomyopes.This study comprised 90 eyes of 45 anisomyopes who were recruited for Colour Doppler imaging (CDI) optical coherence tomography angiography (OCTA). The superficial vessel density (SVD), deep (DVD), thickness (ChT) vascularity, including total area (TCA), luminal (LA), stromal (SA) Choroidal Vascularity Index (CVI), measured using OCTA....

Background: Despite the high breastfeeding initiation rate in China (> 90%), low exclusivity is of concern. Some traditional behaviors, combined with increasing popularity infant formula, may negatively affect future rates. As suggested by theory planned behavior, understanding beliefs young adults help identify and address misperceptions parents, supporting maintenance current while rates duration. No research has evaluated these factors among Mainland China. Objective: The objective was...

To detect variants in 17 known potentially causative genes for non-syndromic myopia 67 Tujia Chinese patients with early-onset high (eo-HM).DNA from unrelated early onset (<7 years old) (refraction error ≤ -6.00D or axial length > 26 mm) were subjected to whole-exome sequencing (WES). Variants candidate analysed by multistep bioinformatics analysis. Subsequently, Sanger was used verify identified mutations and assess available family members co-segregation myopia.A systematic analysis of...

To investigate the characteristics of quick contrast sensitivity function (qCSF) and its related parameters in Chinese ametropia children.This case series study enrolled 106 eyes 53 children (male/female=29/24, age: 9.04±2.06 years). Examinations included manifest refraction, axial length, corneal curvature, monocular binocular qCSF readings without refractive correction (area under log CSF [AULCSF], acuity, [CS] at 1.0 to 18.0 cpd). The subjects were divided into groups according age for...

To investigate the agreement between a mobile applet-based visual acuity (VA) self-test program and conventional VA tests.This consecutive case series study included 121 children adults (242 eyes). Patients were classified into three groups according to age (children, adolescents, adults). They underwent uncorrected distance (UDVA) testing, with available spectacle correction (DVA ASC) testing at 2.5-m distance, near (UNVA) (NVA 0.4-m using tests in two eyes.Correlations among UDVA, DVA ASC,...

To explore changes in the optic disc and peripapillary atrophy (PPA) school-age children with ametropia using color fundus photography combined artificial intelligence (AI) technology.Based on retrospective case-controlled study, 226 eyes of 113 aged 6-12y were enrolled from October 2021 to May 2022. According results spherical equivalent (SE), divided into four groups: low myopia group (66 eyes), moderate (60 high (50 eyes) emmetropia control eyes). All subjects underwent un-aided visual...

Abstract Purpose The morphological changes in the cornea and crystalline lens have not been closely evaluated after administration of atropine 0.01%. This study aims to evaluate radii curvature refractive power myopic eyes during 0.01% treatment. Methods Children aged 6–14 years with myopia &lt;−6.0 D were randomized receive once nightly single vision lenses or simply wear lenses. Ocular biometric parameters measured using IOLMaster 700 biometry corneal lenticular simulated a customized...

To analyze one year clinical outcomes and subjective rating of hybrid bi-aspheric multifocal central presbyLASIK with micro-monovision for correction presbyopia myopic astigmatism.Seventy-four eyes 37 patients consecutively treated were assessed. The mean age the was 43.8±3.0y a spherical equivalent refraction -5.21±1.87 diopters (D) astigmatism -0.82±0.64 D. Visual acuity, manifest refraction, contrast sensitivity, aberrometry patients' evaluated pre- postoperatively.At 1y postoperatively...

To investigate the influence of hydroxyethyl starch solution on exogenous coagulation and active protein C ( APC ) in patients with septic shock.A single-center prospective study was conducted. Eighty-four consecutive shock admitted to intensive care unit ICU Peking University People's Hospital from November 2009 October 2014 were enrolled. The randomized into two groups by random digits table: Ringer lactate group RL group, n = 40 HES 44 ), or hydroxyethl 130/0.4 used for resuscitation...

Abstract Aim To investigate the correlation of angles α and κ with refractive biological parameters in children. Methods This case-series study included 438 eyes 219 children (males/females = 105/114, age: 3–15 years). Ocular biometric parameters, including axial length, corneal radius curvature (CR), white-to-white distance (WTW), angle α, were measured using IOL Master 700; auto-refraction assessed under cycloplegia. The assigned to different groups based on CR, WTW, gender compare κ,...

To investigate the pharmacological accommodative changes of anterior segment and its impact on circumferential chamber angle (ACA) after implantable collamer lens (ICL) implantation using swept-source optical coherence tomography (SS-OCT).

Abstract This study aimed to investigate the awareness of high and pathological myopia among patients with myopia. A cross‐sectional multicenter survey involving both physicians was conducted between February April 2021. The outpatient education status, doctors' expectations toward patient education, patients' high/pathological myopia, their access relevant knowledge were inquired, proportions including assessed. In total, involved 6975 from 161 medical institutions in China. prevalence...

To investigate the prevalence and risk factors of refractive astigmatism (RA) corneal (CA) in preschool children school-aged Shanghai, China.In this school-based, cross-sectional study, 4-15 years old across three learning stages kindergarten, primary school, junior high school underwent noncycloplegic autorefraction completed comprehensive questionnaires involving time spent on daily homework outdoor activities. Data from right eyes were analysed.Overall, 7084 (mean ± standard deviation...

Objective To investigate the effect of wearing orthokeratology lens on ocular accommodation parameters. Methods Seventy patients with myopia were selected from Jan.2014 to Jan.2018. The adjustment amplitude, corneal curvature level, vertical, thickness, naked vision and corrected visual acuity measured before 1 week, 6 months after wearing. Results The range, perpendicularity myopic (9.29±0.36)D, (9.29±0.32)D, (9.28±0.26)D at (40.63±1.32)D, (40.58±1.38)D, (40.50±1.39)D month,...

Abstract Background: To investigate long term safety and efficacy of aspheric micro-monovision LASIK for correction presbyopia myop ic astigmatism. Methods: One hundred fourteen eyes 57 patients with a mean age 48 ± 4.05 years (range: 43 to 62 years) undergoing treatment using the MEL 80 excimer laser (Carl Zeiss Meditec AG, Jena, Germany) were enrolled. Visual acuity, manifest refraction, amplitude accommodation patients’ subjective rating was evaluated from 1 day 3 postoperatively....

Abstract Background : The polymorphisms rs6885224 and rs634990 have been reported to be associated with high myopia in many populations. As there is still no report on whether these two SNPs are the Tujia Miao minority areas of China, we conducted a replication study evaluate association single-nucleotide regions 5p15.2 15q14 Chinese Methods We performed comprehensive meta-analysis 5831 cases 7055 controls assess region myopia. Our enrolled 804 individuals. Genomic DNA was extracted from...

Abstract Background : The polymorphisms rs6885224 and rs634990 have been reported to be associated with high myopia in many populations. As there is still no report on whether these two SNPs are the Tujia Miao minority areas of China, we conducted a replication study evaluate association single-nucleotide regions 5p15.2 15q14 Chinese Methods We performed comprehensive meta-analysis 5831 cases 7055 controls assess region myopia. Our enrolled 804 individuals. Genomic DNA was extracted from...

Abstract Background: To investigate the long-term safety and efficacy of aspheric micro-monovision LASIK for correction presbyopia myopic astigmatism. Methods: In total, 114 eyes 57 patients with a mean age 48 ± 4.05 years (range: 43 to 62 years) who were undergoing treatment enrolled. Visual acuity, manifest refraction, amplitude accommodation, contrast sensitivity, entire eye aberrations patients’ subjective ratings evaluated from 1 day 3 postoperatively. Results: None showed spherical...

Abstract Background In previous studies, rs6885224 and rs634990 polymorphisms have been reported to be associated with high myopia in many populations. Tujia Miao minority area, there is still no report on whether the two SNPs are myopia, so we conducted a replication study evaluate association of single-nucleotide 5p15.2 15q14 regions Chinese Methods We performed comprehensive meta-analysis 3816 cases 4516 controls assess region were myopia. Then total 804 individuals enrolled our study....