Purpose To evaluate corneal reinnervation, and the corresponding sensitivity keratocyte density after small incision lenticule extraction (SMILE) femtosecond laser in situ keratomileusis (FS-LASIK). Methods In this prospective, non-randomized observational study, 18 patients (32 eyes) received SMILE surgery, 22 (42 FS-LASIK surgery to correct myopia. The subbasal nerve microscopic morphological changes architecture were evaluated by confocal microscopy prior at 1 week, month, 3 months, 6...

BACKGROUND AND OBJECTIVE: To compare Asian and Caucasian anterior segment dimensions measured by optical coherence tomography (OCT). PATIENTS METHODS: Anterior OCT images were obtained in normal subjects. Four line scans acquired at the 90°, 45°, 0°, 135° meridians of each eye. Computer calipers corneal diameter, chamber width, vault, depth on images. Univariate multivariate analyses performed to assess correlations. RESULTS: Corneal diameter was 0.5 mm narrower ( P < .01), width 0.46...

To develop an optical coherence tomography (OCT) pachymetry map–based keratoconus risk scoring system.Doheny Eye Institute, University of Southern California, Los Angeles, and Brass Center, New York, USA; Department Ophthalmology, Affiliated Hospital Wenzhou Medical College, Wenzhou, China.Cross-sectional study.Fourier-domain OCT was used to acquire corneal maps in normal subjects. Pachymetric variables were minimum, minimum−median, superior–inferior (S–I), superonasal–inferotemporal...

To evaluate the accuracy of axial length, keratometry, and refractive measurement with Myopia Master in ametropic children.In this randomized prospective cross-sectional study, 125 children ametropia (250 eyes) were recruited (55 boys 70 girls; age range: 3-15 years). All examinations performed under full cycloplegic conditions. Measurements length (AL), autorefraction acquired compared those from IOLMaster 500, 700, Nidek ARK-1, manifest refraction. The differences between different methods...

Aim To investigate the change in posterior corneal elevations (PCEs) of eyes with extremely high myopia 2 years after small incision lenticule extraction (SMILE). Methods We evaluated 39 patients spherical equivalent higher than −10.00 dioptres (D). Using a Scheimpflug camera (Pentacam), we measured PCEs at 1 day, 3 months, 6 months and SMILE. Another 34 who underwent femtosecond laser-assisted situ keratomileusis (FS-LASIK) were examined before, day long-term surgery as control group. For...

SCN1A is the most relevant epilepsy gene. Mutations of generate phenotypes ranging from extremely severe form Dravet syndrome (DS) to a mild generalized with febrile seizures plus (GEFS+). Mosaic mutations have been identified in rare familial DS. It suspected that mosaic may cause other types epilepsies (FS), which are more common clinically. Thus, we screened 13 families partial antecedent (PEFS+) using denaturing high‐performance liquid chromatography and sequencing. The level mosaicism...

Abstract Purpose To investigate early visual and refractive outcomes, corneal stability optical quality after femtosecond laser small‐incision lenticule extraction ( SMILE ) for treating myopia myopic astigmatism over −10 D. Methods Thirty eyes (30 patients) with of D were treated VisuMax ® (version 3.0; Carl Zeiss Meditec AG, Jena, Germany). Six months postoperative safety, efficacy predictability evaluated. Corneal Scheimpflug topography was measured preoperatively, 1 day, 3 6...

To compare the changes in posterior corneal elevation after small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser situ keratomileusis (FS-LASIK) correcting myopia over -9 diopters (D).In this prospective comparative study, 82 eyes of patients scheduled for refractive correction were recruited. Eyes randomly assigned to SMILE group (45 eyes, -10.43±0.92 D) or FS-LASIK (37 -10.97±1.37 D). The surface was measured using a Scheimpflug camera (Pentacam, Oculus, Germany)...

This study compares the clinical outcomes of femtosecond laser small-incision lenticule extraction (SMILE) for correction myopia and myopic astigmatism greater than − 10 D, D or less respectively. 60 eyes/patients were equally selected into group 1 (myopia less) 2 over D), both which treated with SMILE. Visual refractive outcomes, corneal higher-order aberrations, Bowman's layer micro-distortions evaluated preoperatively, 3 months, 6 months postoperatively. LogMAR corrected distance visual...

Purpose: The aim of this study was to explore the optimal method small-incision lenticule extraction (SMILE)-derived lenticules, subjected long-term preservation using glycerol, under a range temperatures, and an array dehydration agents. Methods: In total, 108 myopic lenticules were collected from patients undergoing SMILE procedure. Fresh served as control group for study, whereas all other separated into 8 groups, which preserved at 4 different temperatures (room temperature [RT], 4, −20,...

Purpose: To evaluate the long-term safety, efficacy, predictability, and stability of small incision lenticule extraction (SMILE) for treatment high myopia myopic astigmatism greater than -10.0 D. Methods: This was a prospective study that incorporated 35 consecutive patients (35 eyes) undergoing SMILE from September 2015 to March 2016. These had mean preoperative spherical equivalent refraction -10.06±0.64 Patients were followed over four-year period assessed outcomes including uncorrected...

To evaluate the outcomes in corneal higher-order aberrations (HOAs) and microdistortions Bowman's layer after femtosecond laser small incision lenticule extraction (SMILE) for correcting extremely high myopia.This prospective study included patients with myopia spherical equivalent ≥ -9.0 Diopters (D). SMILE was performed forty eyes of 40 patients. Pentacam used to HOAs before at 1 day, 3 months, 6 2 years surgery. Fourier-domain optical coherence tomography postoperatively. Thirty-two 32...

PURPOSE: To determine the incidence, management, outcomes, and risk factors of suction loss during femtosecond laser small incision lenticule extraction (SMILE) for treatment myopia myopic astigmatism. METHODS: The study reviewed 12,057 consecutive eyes treated with SMILE. Eyes that developed (study group) or underwent uneventful SMILE (control were analyzed. Corneal topography, manifest refractions, measurements uncorrected (UDVA) corrected (CDVA) distance visual acuities evaluated...

To investigate the incidence rate, classification, and management of difficulties in lenticule extraction during small incision (SMILE) with continuous curvilinear lenticulerrhexis (CCL) technique, surgical safety efficacy.Retrospective study. A total 342 subjects (680 eyes) received treatment by same surgeon using SMILE-CCL technique. The separation was performed only between cap anterior surface (8 to 2 o'clock) at edge posterior (1 o'clock). then extracted a clockwise motion CCL Cases...

OBJECTIVE To assess and compare the accuracy regularity short-term change of corneal flap in different preparation styles. METHODS Eighty eyes 40 cases were treated with laser-assisted subepithelial keratectomy. One hundred fifty-five 78 laser situ keratomileusis 90 microm microkeratome eighty-two 42 100 femtosecond preparation. Anterior segment optical coherence tomography was used to thickness epithelial or stromal flaps created M2 VisuMax by same investigator 1 hour, day, week, month 3...

Post-laser-assisted

This present study investigated the chemical influence on water retention curves of compacted GMZ bentonite. Sodium chloride solution and calcium were mixed with bentonite before compaction. Water determined by measuring suctions a high-precision humidity sensor. The influences predominant in suction range less than 70 MPa. In range, an increasing salinity resulted upward movement curve, i.e. capability type also had notable behaviour. A higher added was observed compared to that sodium...

Abstract Spleen‐stomach dampness‐heat syndrome (SSDHS) is the common Traditional Chinese Medicine (TCM) observed in both chronic hepatitis B (CHB) and gastritis (CG). The specialized TCM prescription for CHB CG patients with SSDHS same, but there limited information about biological characteristics of this syndrome. This study aimed to identify serum miRNAs profile two different diseases order evaluate miRNA‐mediated We performed comparative microarray analysis miRNA expression profiles 10...