- HIV/AIDS Research and Interventions
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- Sodium Intake and Health
- ECG Monitoring and Analysis
- Family Caregiving in Mental Illness
- HIV, Drug Use, Sexual Risk
- Vascular anomalies and interventions
- HIV/AIDS drug development and treatment
- Erythropoietin and Anemia Treatment
- Cardiac electrophysiology and arrhythmias
- Thyroid and Parathyroid Surgery
- Obstructive Sleep Apnea Research
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Tracheal and airway disorders
- Thyroid Disorders and Treatments
- Cardiovascular Health and Risk Factors
- Adolescent and Pediatric Healthcare
- COVID-19 Clinical Research Studies
- Thyroid Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Sleep and related disorders
Lagos State University Teaching Hospital
2020-2024
Lagos State University
2010-2024
Obafemi Awolowo University Teaching Hospitals Complex
2007-2015
Ladoke Akintola University of Technology
2010
Objective: Despite the fact that two-thirds of all people with HIV live in sub-Saharan Africa, little is known about emotional state and quality life (QOL) subjects this region. The objective study was to evaluate association between clinical depression a group sero-positive Nigeria. Methods: Subjects infection ( n=87) completed questionnaire detailing sociodemographic related variables. were assessed for diagnosis using Mini International Neuropsychiatric Interview (MINI) their subjective...
Background: Facilities for Holter electrocardiography (ECG) monitoring in many Nigerian hospitals are limited. There few published works Nigeria on the use of 24-hour ECG cardiac arrhythmic evaluation patients with cardiovascular diseases. Objective: To study clinical indications, pattern, and heart rate variability (HRV) among subjects referred at our Cardiac Care Unit. Methods: Three-hundred ten (134 males 176 females) were studied consecutively over a 48-month period using Schiller type...
This study investigated plasma sodium/potassium ratio, markers of oxidative stress, renal function, and endothelial dysfunction in hypertensive Nigerians.Five hundred forty-nine volunteers consisting three twenty-four two twenty-five controls participated this study. Blood samples were collected from the participants analyzed for electrolytes, dysfunction, inflammation, using ion-selective electrodes, spectrophotometric, enzyme-linked immunosorbent assay methods, respectively.The mean...
Background: Many specific and non-specific electrocardiographic abnormalities including ventricular arrhythmias have been reported in subjects with sickle cell anemia (SCA). In SCA patients, cardiac electrical may be the leading cause of increased risk arrhythmias. The corrected QT (QTc) interval, peak to end T wave (Tp-e) interval associated Tp-e/QTc ratio are promising measures altered repolarization arrhythmogenesis risk. Aim: This study assessed using QTc Tp-e ratio, also evaluated...
In patients with heart failure, death is often sudden due to life-threatening arrhythmias. This work was carried out evaluate the pattern of arrhythmias in Nigerians failure.Thirty subjects congestive failure (CHF), 30 hypertensive disease, and 15 normal no obvious features disease were evaluated resting 24-hour electrocardiographic monitoring transthoracic echocardiography. Data analyzed one-way analysis variance post hoc Duncan's analysis, Fisher's exact test, linear regression using SPSS...
Suicidal behaviour is an established psychiatric complication of congestive cardiac failure (CCF), contributing significantly to morbidity and death by suicide. The magnitude risk factors for suicidal among patients with CCF are yet be unpacked, especially in developing nations such as Nigeria.
<title>Abstract</title> Introduction Obesity is a metabolic disorder characterized by complex interplay of genetic predisposition as well socioeconomic and behavioral influences. This study aims to understand how anthropometric measures predict the risk syndrome among individuals with Type 2 DM using BMI, waist circumference, waist-to-hip ratio, waist-to-height ratio. Methodology The retrospective cross-sectional used medical records 202 patients being managed for at Lagos State University...
Objectives: Hypertension is a major risk factor for cardiovascular morbidity and mortality; thus, proper monitoring of blood pressure (BP) control essential to reduce the burden diseases. Despite advocacy use 24-hour ambulatory BP monitors (ABPMs), their routine in this environment still suboptimal. This study, therefore, sets out determine proportion hypertensive patients on therapy who have good with both office value ABPM parameters. Material Methods: study was cross-sectional 235...
Background: The 24-h ambulatory holter electrocardiogram (ECG) monitor is particularly able to document bradyarrhythmic or tachyarrhythmic episodes which might be missed on normal 12-lead resting ECG recordings. It is, therefore, useful in evaluating patients with symptomatic asymptomatic paroxysmal tachy/bradyarrhythmias and also monitoring antiarrhythmic therapy. present study was aimed at presenting our findings the prevalence of arrhythmias Holter a relatively large cohort referred...
Introduction: paraoxonase 1 (PON1) is a high-density lipoprotein (HDL) associated enzyme that has anti-inflammatory, anti-atherogenic, and antioxidant functions. PON1 noted to be determinant of resistance the development atherosclerosis through hydrolysis phospholipid cholesteryl ester hydroperoxides. This study was designed assess activity levels among patients with type 2 diabetes mellitus (T2DM) in Southwest Nigeria.
Abstract Double-outlet right ventricle (DORV) is a complex and rare congenital heart disease (CHD), which usually symptomatic early in childhood thus diagnosed early. Dextrocardia another CHD that can occur either as an isolated cardiac abnormality or may be associated with other defects. However, the co-occurrence of DORV dextrocardia rare, especially adult life. We present 35-year-old Nigerian lady situs inversus totalis CHD, included multiple intracardiac shunts, occurring...
Background: The prevalence of acute coronary syndrome (ACS) in Nigeria is on the rise with dire morbidity and mortality risks. Cardiac biomarkers are rapid sensitive tools used as adjunct diagnosis ACS. clinical utility cardiac yet to be well explored Nigerian setting.
 Objectives: To determine indications their electrocardiographic (ECG) changes.
 Methods: This study a retrospective review all patients who had point-of-care serum Troponin-I, Creatine kinase MB isoenzyme myoglobin...
Context: Hypertension is a disease of global public health importance affecting an estimated 1 billion people worldwide. accounts for about 10.4 million deaths in 2017. Many guidelines are available the management hypertension, but despite this, there wide variations physicians' choice antihypertensive medications blood pressure (BP) control. Aims: We reviewed prescription pattern medication and level BP control patients with hypertension. Settings Design: This cross-sectional study among...
Obstructive sleep apnea (OSA) is a common chronic disorder that decreases the quality of life patients. It an underdiagnosed medical condition in Nigeria. This study aimed to describe clinical presentations and validate screening questionnaires with home for diagnosis patients suspected OSA seen Lagos. was descriptive cross sectional carried out on adult suspicion referred Respiratory Clinic Lagos State University Teaching Hospital. A proforma used obtain information also data from...
Cardiac catheterization is useful in the diagnosis and treatment of congenital acquired cardiac diseases. However, it rarely done Nigeria because limited laboratories country. Transforming existing operating theaters to modified may bridge gap catheterization. This study reviewed procedures, outcomes, challenges a laboratory Nigeria. A retrospective review all diagnostic catheterizations at Lagos State University Teaching Hospital (LASUTH) between January May 2022 was performed. total 8...
<b>Background</b>: COVID-19 disease is associated with long-term effects in some survivors. There exists dearth of information about the burden respiratory morbidity among survivors Nigeria. This study was designed to identify common symptoms long educate and increase index suspicion healthcare practitioners caring for such patient optimal care.<br /> <b>Material methods</b>: a cross-sectional survey that took place at adult pulmonology clinic Lagos State...
BACKGROUND: Anaemia and abnormal left ventricular (LV) geometric pattern are common findings in Chronic Kidney disease (CKD) patients.
 OBJECTIVES: To assess LV its relationship with anaemia among CKD METHODS: A cross sectional study of 163 subjects (102 61 without respectively). Echocardiography determined the while packed cell volume (PCV) levels anaemia.
 RESULTS: The mean age was 54.04 ± 14.47 54.92 15.67 years respectively (p = 0.717) prevalence LVH two groups 68.8% 57.9%...