Preeclampsia is a pregnancy specific syndrome. Studies have shown that preeclampsia has multiorgan dysfunction effects. This study evaluated biomarkers of renal and liver function among preeclamptic Nigerian women. was cross-sectional conducted 49 women 50 normotensive healthy pregnant The baseline data comprising age, gestational blood pressure were obtained. Venous spot urine samples collected from each participant. Plasma obtained taken into lithium heparinized vacutainer bottles assayed...

Football sporting exercise is one of the most popular events in world. While there are well-documented reports on effects different athletic activities biochemical markers renal and liver functions, paucity football activity Nigerian sportsmen, hence need for this study.Biochemical functions (urea, creatinine, aspartate aminotransaminase (AST), alanine (ALT), alkaline phosphatase (ALP)) were determined using Cobas c 111 auto-analyser by Roche.The mean urea (mmol/L)±SEM, creatinine...

BACKGROUND:Preeclampsia is a multifaceted pregnancy-related disorder affecting women and fetuses. A link between preeclampsia, oxidative stress, inflammation has been suggested. This study evaluated the interrelationship biomarkers of inflammation, hematological parameters among preeclamptic Nigerian women. MATERIAL AND METHODS:A cross-sectional was conducted 49 50 normotensive healthy pregnant Blood samples were obtained after 20-week gestation in all participants. Levels superoxide...

highly active antiretroviral therapy (HAART) has led to a decline in HIV-induced morbidity and mortality recent years. However, it been opined that this elevated risks of cardiovascular diseases (CVDs). This study assessed the CVDs among HAART experienced individuals living with HIV.

Diabetes mellitus is gradually becoming a major health burden in Nigeria, partly due to westernization of our diet and life style. It affects both young old people when not properly managed may lead complications. Thus there need for quick, convenient cheap means monitoring blood glucose level optimum management. This study aimed at comparing some point-of-care testing devices with laboratory method. A total 150 volunteers participated this study. Laboratory determination was carried out on...

This study investigated plasma sodium/potassium ratio, markers of oxidative stress, renal function, and endothelial dysfunction in hypertensive Nigerians.Five hundred forty-nine volunteers consisting three twenty-four two twenty-five controls participated this study. Blood samples were collected from the participants analyzed for electrolytes, dysfunction, inflammation, using ion-selective electrodes, spectrophotometric, enzyme-linked immunosorbent assay methods, respectively.The mean...

Diabetes mellitus is a chronic and progressive endocrine disorder that may result in macro microvascular complications.This study assessed some biochemical analytes Nigerians who were recently (≤ 6 months) diagnosed with Type 2 diabetes (T2DM).160 T2DM 90 non-diabetic control participated this study. Blood samples collected analyzed for Heart-type fatty acid-binding protein (HFABP), high sensitivity C-reactive (hs-CRP), electrolytes, lipid renal profile parameters, glycated haemoglobin...

Background and Purpose: Hypertension is a major medical condition that can cause many complications sudden death when not appropriately controlled. This study determined serum calcium, parathyroid hormone, vitamin D, renin, angiotensin II, I converting enzyme, aldosterone in hypertensive individuals, as these compounds play key roles regulating human blood pressure. Materials Methods: case-control was conducted on 549 (324 cases 225 controls) individuals between October 2018 September 2020....

Purpose Pre-eclampsia and eclampsia (PE/E) are rising in Sub-Saharan Africa, including Nigeria. This study aims to evaluate the availability logistics management of sixteen items from Nigerian essential medicine list required for managing these conditions. Design/Methodology/approach A cross-sectional 50 health-care facilities Lagos State, Nigeria, at beginning COVID-19 pandemic by interviewing facility’s main person charge health commodities. Data were recorded during visit previous six...

Background: Previous reports showed that infrared radiation (IR) involved in photoaging, photocarcinogenesis, free radicals' production, and depletion of bone marrow cells. Beneficial effects moderate exposure to lamp have been itemized include enhancement blood circulation, relief from muscular pain, wound healing acceleration with scarce information on biological when it is overexposed. Therefore, there a need investigate the possibility its overexposure system, especially parameters. Aim:...

[b]BACKGROUND[/b] Thyroid hormones and N-terminal pro-brain natriuretic peptide play critical roles in cardiac function, the direct relationship between thyroid hormone blood pressure is well documented. This study was designed to evaluate ability of predict risk heart failure among hypertensive patients Nigeria. [b]MATERIAL AND METHODS[/b] A cross-sectional conducted on 212 volunteers (120 age- sex-matched subjects with hypertension, 53 normotensive as controls, 39 failure). Blood samples...

Hypertension is gradually becoming a major health burden in Nigeria; the most populous African nation. Often this starts unnoticed, but later, disorder leads to complications and death if not properly managed. This study assessed level of peroxisome proliferator-activated receptor-gamma (PPAR-γ), insulin, glucose lipid profile components hypertensive Nigerians. A total number four hundred nineteen volunteers consisting two fifteen (215) (204) normotensive participants (of which sixty (260)...

BackgroundIn pregnancy, women experience physiological changes which could increase the risk of insulin resistance, and metabolic syndrome later in life. This study assessed future among pregnant with either glycosuria or proteinuria at different gestational ages. MethodsEight-Six participants were recruited from health facilities South-west, Nigeria they three categories: those (n = 32), 27), control based on urinalysis result. Data analyzed using IBM SPSS Statistics for Windows version...

High blood pressure is a medical condition characterized with persistent elevated systolic and or diastolic pressure. It usually presents no symptom in most cases if untreated it eventually leads to complications. Thus the aim of this study evaluate possible effect high on male reproductive hormones level. A total number one hundred ten volunteers between ages 18-55years participated study. Out this, sixty were hypertensive without previous knowledge as at time hence not antihypertensive...

Diabetes mellitus is a serious metabolic disorder of multiple aetiology. This on the increase in some developing countries such as Nigeria. It characterized by chronic hyperglycaemia with disturbances carbohydrate, fat and protein metabolism resulting from either defects insulin secretion, action or both.In cases, disease may be insidious until patients develop complications. A total number three hundred seventy five individuals participated this study out which two twenty were type 2...

Background: Elevated plasma levels of ferritin and oxidative stress have been associated with diabetic nephropathy; the onset which is insidious. The early stages glomerular hyper filtration often go unnoticed in majority subjects. This limit precision creatinine based rate estimates. Objective: We sought to document role markers detection nephropathy diabetes mellitus (DM). Subjects Methods: was a cross sectional analytical study conducted on 360 participants, comprising 220 DM 140 age...

Background: Hypertension is a chronic disease that has been recognized as an important global public health disorder. It leading risk factor for stroke, heart failure, kidney diseases, and sudden death; such its effective management may go long way in preventing some of these possible complications. In humans, trace elements play key roles normal metabolic activities are required healthy living. hypothesized to functions. Thus, deficiency one or more result(s) accentuate disease(s). This...

Background: A link between major depressive disorder (MDD) and haematological as well co-agulation disorders has been postulated. This study aims to evaluate haemostatic changes among Nigerians with Methods: Two hundred volunteers consisting of an equal number individuals diagnosed based on DMS-IV criteria apparently healthy control participated in this study. The blood sample was collected into tri-sodium citrate K2EDTA bottles respectively evaluated for some parameters , using ELISA,...