- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- COVID-19 Clinical Research Studies
- Retinopathy of Prematurity Studies
- Pregnancy and preeclampsia studies
- Genetics and Neurodevelopmental Disorders
- Mosquito-borne diseases and control
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Infant Nutrition and Health
- Respiratory viral infections research
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Child Nutrition and Water Access
- Pneumonia and Respiratory Infections
- COVID-19 Impact on Reproduction
- Child and Adolescent Health
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Blood donation and transfusion practices
- Ovarian function and disorders
- Hernia repair and management
- Congenital Heart Disease Studies
- Tuberculosis Research and Epidemiology
National Institute of Neurosciences & Hospital
2020-2025
Dhaka Medical College and Hospital
2024
University of Barisal
2024
Dhaka Shishu Hospital
1970-2023
Hamdard University Bangladesh
2019-2022
Sylhet MAG Osmani Medical College
2013-2021
Universal College
2021
Bangabandhu Sheikh Mujib Medical University
2018-2021
North China University of Science and Technology
2016
Introduction: Copy number variations (CNVs) play a critical role in the pathogenesis of neurodevelopmental disorders (NDD) among children. In this study, we aim to identify clinically relevant CNVs, genes and their phenotypic characteristics an ethnically underrepresented homogenous population Bangladesh. Methods: We have conducted chromosomal microarray analysis (CMA) for 212 NDD patients with male female ratio 2.2:1.0 rare CNVs. To candidate within gene constraint metrics [i.e.,...
A disintegrin and metalloproteinase-17 (ADAM17) can cut release a wide variety of epidermal growth factor receptor (EGFR) ligands to promote survival, invasion proliferation cancer cell, therefore, is considered be potential therapeutic target for cancer. The main goal the present study was observe effects ADAM17 small interfering RNA (ADAM17-siRNA) on human MCF-7 breast investigate its activation pathway. In vitro, cells were divided into ADAM17-siRNA groups, nonsense siRNA AG1478...
Background: There has been epidemics of bronchiolitis in the recent years Bangladesh. Bronchiolitis is mostly (95%) a viral disease infants and young children but being treated with antibiotics 99% cases our situation. Antibiotic little role management bronchiolitis. Very few randomized control trials without have so far done. Objectives: To evaluate outcome or hospital setting. Methods: A trial was done during one winter season 2005 all attending teaching Dhaka, Sample size selected...
Background: An organ or fatty tissue, like the colon, might abnormally emerge through wall of cavity in which it normally resides, for making a hernia. Among different hernias inguinal hernia repair is most frequently done procedures by surgeons Bangladesh and worldwide. Now-a-days Laparoscopic performed this country accepted people. TEP e-TEP are excellent procedure In Centre, we both procedures. Technical aspects better approachable than TEP. Objective: article present how to overcome...
Coronavirus disease 2019 (COVID-19), due to SARS-CoV-2 infection, has been a global concern since January 2020. Southeast Asia, including Bangladesh, is facing outbreaks of endemic diseases such as dengue. Here, we report the case an eight-year-old female from Dhaka with high-grade, continued fever, shock, features pneumonia, and plasma leakage multiple organ dysfunction. Both nonstructural protein 1 antigen (NS1 Ag) for dengue reverse transcription-polymerase chain reaction (RT-PCR)...
Introduction To evaluate WHO chest radiograph interpretation processes during a pneumococcal vaccine effectiveness study of children aged 3–35 months with suspected pneumonia in Sylhet, Bangladesh. Methods Eight physicians masked to all data were standardised methodology and interpreted radiographs between 2015 2017. Each was randomly assigned two primary readers. If the readers discordant for image interpretability or presence absence endpoint (PEP), then another selected, reader...
Hepatitis B virus infection is a vaccine preventable of liver which remains key public health burden globally. The development Anti-HBs titre greater than or equal to 10 IU/L considered as protective immunity and any less non-protective following HBV vaccination. There no comprehensive authentic data regarding the immune response even years after integration in EPI programme Bangladesh specifically, Brahmonbaria district. study was also aimed assess long term among vaccinated children. Blood...
Background: Preterm birth is associated with variable degree of brain injury and adverse neurodevelopmental outcomes. Therefore, screening these infants required to assess further abnormalities. Cranial ultrasound finding has been a predictor outcome in this population.Objective: The present study was carried out find cranial abnormalities preterm neonates aid at risk for long term neurodevelopmenal impairment.Materials Methods: This observational conducted Dhaka Shishu (Children) Hospital...
Background: Retinopathy of prematurity (ROP) is a retinal vascular disorder preterm neonates resulting in visual impairement. Along with prematurity, very low birth weight and hyperoxia, role blood transfusions the occurrence ROP has been strongly emphasized. Objective: To determine relationship timing volume transfusion other factors development (VLBW) newborn infants. Methods: This was prospective observational study. It done among premature (<34 weeks) VLBW admitted to SCABU ICU Dhaka...
Background: Preterm infants are at risk for long term neurodevelopmental impairements. Neurodevelopmental assessment early months of infancy has been proposed as a valuable tool prediction outcomes in this population.Objective: The present study attempted to find the impairments preterm and thus identify follow up subsequent therapeutic intervention.Methodology: This prospective cross-sectional observational was conducted Dhaka Shishu (Children) Hospital from October 2011 March, 2012. A...
Arthrogryposis is a medical term used to describe congenital contractures which often affect multiple limbs. Distal arthrogryposis (DA) one of the major categories that primarily affects distal parts body, i.e., hands and legs. Although ten different types several subtypes DAs have been described, genes associated with each these are yet be characterized. type 10 (DA10) rare genetic disease, distinguished from other by plantar flexion resulting in toe-walking during infancy as well...
Febrile seizure (FS) is one of the most common seizures seen in infant and pre-school age. There are two types FSs, simple complex. Simple FS commonly benign, but complex have long-term effects. Most children with normal growth development after attack; however, recent evidences suggest that a small group presenting fever may subsequently develop epilepsy or recurrent seizures. Diagnosis mainly based on clinical presentation, electroencephalogram, lumbar puncture, neuroimaging, which can be...
Background: There is a popular believe that cardiac murmurs are common in neonate and most innocent or physiological. However, murmur may be the first sign of serious structural disease neonate. Objective: This study was conducted to determine clinical significance as sole Methodology: Fifty neonates having were selected from in-patient department Dhaka Shishu Hospital March 06 October 06. Murmurs clinically classified significant murmur. Echocardiography done for confirmation diagnosis...
Background: An organ or fatty tissue, like the colon, might abnormally emerge through wall of cavity in which it normally dwells, a condition known as hernia. Inguinal hernia repair is among most frequently done procedures by surgeons worldwide. Treatment includes pure tissue repairs to prosthetic under open laparoscopic approach. Though so many options are available but none superior others. Aim study compare effectiveness with mesh repair. Methods: The was comparative cross-sectional...